5ZEV

Solution structure of G-quadruplex formed in vegfr-2 proximal promoter sequence

Summary for 5ZEV

• Entry DOI: 10.2210/pdb5zev/pdb
• NMR Information: BMRB: 36168
• Descriptor: DNA (5'-D(*GP*GP*GP*TP*AP*CP*CP*CP*GP*GP*GP*TP*GP*AP*GP*GP*TP*GP*CP*GP*GP*GP*GP*T)-3') (1 entity in total)
• Functional Keywords: g-quadruplex vegfr-2 dna, dna
• Biological source: synthetic construct
• Total number of polymer chains: 1
• Total formula weight: 7563.84

Authors

Liu, Y.,Lan, W.X. (deposition date: 2018-02-28, release date: 2018-04-18, Last modification date: 2023-06-14)

• Primary citation: Liu, Y.,Lan, W.,Wang, C.,Cao, C.; A putative G-quadruplex structure in the proximal promoter ofVEGFR-2has implications for drug design to inhibit tumor angiogenesis.; J. Biol. Chem., 293:8947-8955, 2018; PubMed: 29666187; DOI: 10.1074/jbc.RA118.002666

Experimental method

SOLUTION NMR