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1Q1S
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BU of 1q1s by Molmil
Mouse Importin alpha- phosphorylated SV40 CN peptide complex
Descriptor: Importin alpha-2 subunit, Large T antigen
Authors:Fontes, M.R.M, Teh, T, Toth, G, John, A, Pavo, I, Jans, D.A, Kobe, B.
Deposit date:2003-07-22
Release date:2004-03-30
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha
Biochem.J., 375, 2003
1QZ7
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BU of 1qz7 by Molmil
Beta-catenin binding domain of Axin in complex with beta-catenin
Descriptor: Axin, Beta-catenin
Authors:Xing, Y, Clements, W.K, Kimelman, D, Xu, W.
Deposit date:2003-09-15
Release date:2003-11-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a beta-catenin/Axin complex suggests a mechanism for the {beta}-catenin destruction complex
GENES DEV., 17, 2003
3Q5U
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BU of 3q5u by Molmil
A minimal NLS from human scramblase 4 complexed with importin alpha
Descriptor: Importin subunit alpha-2, Phospholipid scramblase 4
Authors:Bhardwaj, A, Cingolani, G.
Deposit date:2010-12-29
Release date:2011-06-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A Minimal Nuclear Localization Signal (NLS) in Human Phospholipid Scramblase 4 That Binds Only the Minor NLS-binding Site of Importin {alpha}1.
J.Biol.Chem., 286, 2011
7LET
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BU of 7let by Molmil
Structure of importin a2 bound to the p50- and p65-NLSs
Descriptor: Importin subunit alpha-1, Nuclear factor NF-kappa-B p105 subunit, Transcription factor p65
Authors:Florio, T.J, Lokareddy, R.K, Cingolani, G.
Deposit date:2021-01-15
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Differential recognition of canonical NF-kappa B dimers by Importin alpha 3.
Nat Commun, 13, 2022
7LEQ
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BU of 7leq by Molmil
Structure of importin a2 bound to p50 NLS
Descriptor: Importin subunit alpha-1, Nuclear factor NF-kappa-B p105 subunit
Authors:Florio, T.J, Lokareddy, R.K, Cingolani, G.
Deposit date:2021-01-14
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Differential recognition of canonical NF-kappa B dimers by Importin alpha 3.
Nat Commun, 13, 2022
7LEU
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BU of 7leu by Molmil
Structure of importin a2 bound to p65-NLS
Descriptor: Importin subunit alpha-1, Transcription factor p65
Authors:Florio, T.J, Lokareddy, R.K, Cingolani, G.
Deposit date:2021-01-15
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Differential recognition of canonical NF-kappa B dimers by Importin alpha 3.
Nat Commun, 13, 2022
7LFC
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BU of 7lfc by Molmil
Structure of importin a3 bound to p50 NLS
Descriptor: Importin subunit alpha-3, Nuclear factor NF-kappa-B p105 subunit
Authors:Florio, T.J, Lokareddy, R.K, Cingolani, G.
Deposit date:2021-01-16
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Differential recognition of canonical NF-kappa B dimers by Importin alpha 3.
Nat Commun, 13, 2022
7LF4
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BU of 7lf4 by Molmil
Structure of importin a3 bound to the p50- and p65-NLSs
Descriptor: Importin subunit alpha-3, Nuclear factor NF-kappa-B p105 subunit, Transcription factor p65
Authors:Florio, T.J, Lokareddy, R.K, Cingolani, G.
Deposit date:2021-01-15
Release date:2022-01-19
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Differential recognition of canonical NF-kappa B dimers by Importin alpha 3.
Nat Commun, 13, 2022
7M60
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BU of 7m60 by Molmil
Structure of Mouse Importin alpha MLH1-S467A NLS Peptide Complex
Descriptor: DNA mismatch repair protein Mlh1 NLS peptide, Importin subunit alpha-1
Authors:De Oliveira, H.C, Da Silva, T.D, Fukuda, C.A, Fontes, M.R.M.
Deposit date:2021-03-25
Release date:2021-07-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and calorimetric studies reveal specific determinants for the binding of a high-affinity NLS to mammalian importin-alpha.
Biochem.J., 478, 2021
6BW9
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BU of 6bw9 by Molmil
Hendra virus W protein C-terminus in complex with Importin alpha 3 crystal form 1
Descriptor: Importin subunit alpha-3, Protein W
Authors:Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
Deposit date:2017-12-14
Release date:2018-07-04
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
6BW0
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BU of 6bw0 by Molmil
Nipah virus W protein C-terminus in complex with Importin alpha 1
Descriptor: Importin subunit alpha-1, Protein W
Authors:Smith, K.M, Tsimbalyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
Deposit date:2017-12-14
Release date:2018-07-04
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
6BWB
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BU of 6bwb by Molmil
Hendra virus W protein C-terminus in complex with Importin alpha 3 crystal form 3
Descriptor: Importin subunit alpha-3, Protein W
Authors:Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
Deposit date:2017-12-14
Release date:2018-07-04
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
6BWA
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BU of 6bwa by Molmil
Hendra virus W protein C-terminus in complex with Importin alpha 3 crystal form 2
Descriptor: Importin subunit alpha-3, Protein W
Authors:Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
Deposit date:2017-12-14
Release date:2018-07-04
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
6BVT
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BU of 6bvt by Molmil
Importin alpha 1 in cargo free state
Descriptor: Importin subunit alpha-1
Authors:Smith, K.M, Tsimablyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
Deposit date:2017-12-13
Release date:2018-07-04
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
3RZX
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BU of 3rzx by Molmil
Mouse importin alpha-Ku70 NLS peptide complex
Descriptor: Importin subunit alpha-2, Ku70 NLS peptide
Authors:Takeda, A.A.S, Fontes, M.R.M.
Deposit date:2011-05-12
Release date:2011-08-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Structural basis of importin-alpha-mediated nuclear transport for Ku70 and Ku80.
J.Mol.Biol., 412, 2011
3SL9
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BU of 3sl9 by Molmil
X-ray structure of Beta catenin in complex with Bcl9
Descriptor: 1,2-ETHANEDIOL, B-cell CLL/lymphoma 9 protein, Catenin beta-1, ...
Authors:Gupta, D, Bienz, M.
Deposit date:2011-06-24
Release date:2012-02-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:An intrinsically labile alpha-helix abutting the BCL9-binding site of beta-catenin is required for its inhibition by carnosic acid.
Nat Commun, 3, 2012
7NSC
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BU of 7nsc by Molmil
Substrate receptor scaffolding module of human CTLH E3 ubiquitin ligase
Descriptor: Glucose-induced degradation protein 4 homolog, Glucose-induced degradation protein 8 homolog, Isoform 2 of Armadillo repeat-containing protein 8, ...
Authors:Chrustowicz, J, Sherpa, D, Prabu, J.R, Schulman, B.A.
Deposit date:2021-03-05
Release date:2021-05-05
Last modified:2021-06-16
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme.
Mol.Cell, 81, 2021
6BVZ
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BU of 6bvz by Molmil
Importin alpha 3 in cargo free state
Descriptor: Importin subunit alpha-3
Authors:Smith, K.M, Tsimbalyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
Deposit date:2017-12-14
Release date:2018-07-04
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
6BW1
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BU of 6bw1 by Molmil
Hendra virus W protein C-terminus in complex with Importin alpha 1
Descriptor: Importin subunit alpha-1, Protein W
Authors:Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
Deposit date:2017-12-14
Release date:2018-07-04
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
7N8J
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BU of 7n8j by Molmil
Human importin alpha 1 in complex with Bimax2 peptide
Descriptor: BIMAX2, Importin subunit alpha-1
Authors:Donnelly, C.M, Cross, E.M, Tsimbalyuk, S, Forwood, J.K.
Deposit date:2021-06-15
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Human importin alpha 1:Bimax2 peptide complex
To Be Published
3QHE
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BU of 3qhe by Molmil
Crystal structure of the complex between the armadillo repeat domain of adenomatous polyposis coli and the tyrosine-rich domain of Sam68
Descriptor: Adenomatous polyposis coli protein, KH domain-containing, RNA-binding, ...
Authors:Morishita, E.C.J, Murayama, K, Kato-Murayama, M, Ishizuku-Katsura, Y, Tomabechi, Y, Terada, T, Handa, N, Shirouzu, M, Akiyama, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2011-01-25
Release date:2011-11-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of the armadillo repeat domain of adenomatous polyposis coli and its complex with the tyrosine-rich domain of sam68
Structure, 19, 2011
6D7N
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BU of 6d7n by Molmil
Crystal structure of the W357R/W399R Importin alpha mutant
Descriptor: 1,2-ETHANEDIOL, Peroxidase,Importin subunit alpha-1
Authors:Pedersen, L.C, London, R.E, Gabel, S.A.
Deposit date:2018-04-25
Release date:2019-03-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Variations in nuclear localization strategies among pol X family enzymes.
Traffic, 2018
7N9H
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BU of 7n9h by Molmil
Structure of the mammalian importin a1 bound to the TDP-43 NLS
Descriptor: Importin subunit alpha-1, TAR DNA-binding protein 43
Authors:Doll, S.G, Lokareddy, R.K, Cingolani, G.
Deposit date:2021-06-17
Release date:2022-06-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Recognition of the TDP-43 nuclear localization signal by importin alpha 1/ beta.
Cell Rep, 39, 2022
6BVV
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BU of 6bvv by Molmil
Nipah virus W protein C-terminus in complex with Importin alpha 3
Descriptor: Importin subunit alpha-3, Protein W
Authors:Smith, K.M, Tsimbalyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
Deposit date:2017-12-13
Release date:2018-07-04
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
6D7M
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BU of 6d7m by Molmil
Crystal structure of the W184R/W231R Importin alpha mutant
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Peroxidase,Importin subunit alpha-1, ...
Authors:Pedersen, L.C, London, R.E, Gabel, S.A.
Deposit date:2018-04-25
Release date:2019-03-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.187 Å)
Cite:Variations in nuclear localization strategies among pol X family enzymes.
Traffic, 2018

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