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2YYH
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Crystal structure of Nudix family protein from Aquifex aeolicus
Descriptor: 8-OXO-dGTPase domain
Authors:Nakagawa, N, Kishishita, S, Yokoyama, S, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-30
Release date:2007-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of Nudix family protein from Aquifex aeolicus
To be Published
2YVP
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Crystal structure of NDX2 in complex with MG2+ and ampcpr from thermus thermophilus HB8
Descriptor: MAGNESIUM ION, METHYLENE ADP-BETA-XYLOSE, MutT/nudix family protein
Authors:Wakamatsu, T, Nakagawa, N, Kuramitsu, S, Yokoyama, S, Masui, R, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-13
Release date:2008-02-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structural basis for different substrate specificities of two ADP-ribose pyrophosphatases from Thermus thermophilus HB8
J.Bacteriol., 190, 2008
2YVN
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BU of 2yvn by Molmil
Crystal structure of NDX2 from thermus thermophilus HB8
Descriptor: MutT/nudix family protein
Authors:Wakamatsu, T, Nakagawa, N, Kuramitsu, S, Yokoyama, S, Masui, R, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-13
Release date:2008-02-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Structural basis for different substrate specificities of two ADP-ribose pyrophosphatases from Thermus thermophilus HB8
J.Bacteriol., 190, 2008
2YVM
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BU of 2yvm by Molmil
Crystal structure of NDX2 in complex with MG2+ from thermus thermophilus HB8
Descriptor: MAGNESIUM ION, MutT/nudix family protein
Authors:Wakamatsu, T, Nakagawa, N, Kuramitsu, S, Yokoyama, S, Masui, R, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-13
Release date:2008-02-26
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for different substrate specificities of two ADP-ribose pyrophosphatases from Thermus thermophilus HB8
J.Bacteriol., 190, 2008
4HVY
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BU of 4hvy by Molmil
A thermostable variant of human NUDT18 NUDIX domain obtained by Hot Colony Filtration
Descriptor: GLYCEROL, MAGNESIUM ION, Nucleoside diphosphate-linked moiety X motif 18, ...
Authors:Asial, I, Cheng, Y.X, Engman, H, Wu, B, Dollhopf, M, Nordlund, P, Cornvik, T.
Deposit date:2012-11-07
Release date:2014-01-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Engineering protein thermostability using a generic activity-independent biophysical screen inside the cell.
Nat Commun, 4, 2013
3A6V
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BU of 3a6v by Molmil
Crystal structure of the MutT protein in MN(II) bound holo form
Descriptor: L(+)-TARTARIC ACID, MANGANESE (II) ION, Mutator mutT protein, ...
Authors:Nakamura, T, Yamagata, Y.
Deposit date:2009-09-09
Release date:2009-10-27
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and dynamic features of the MutT protein in the recognition of nucleotides with the mutagenic 8-oxoguanine base
J.Biol.Chem., 285, 2010
3A6T
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BU of 3a6t by Molmil
Crystal structure of MutT-8-OXO-DGMP complex
Descriptor: 8-OXO-2'-DEOXY-GUANOSINE-5'-MONOPHOSPHATE, Mutator mutT protein, SODIUM ION, ...
Authors:Nakamura, T, Yamagata, Y.
Deposit date:2009-09-09
Release date:2009-10-27
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Structural and dynamic features of the MutT protein in the recognition of nucleotides with the mutagenic 8-oxoguanine base
J.Biol.Chem., 285, 2010
4JZT
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BU of 4jzt by Molmil
Crystal structure of the Bacillus subtilis pyrophosphohydrolase BsRppH (E68A mutant) bound to GTP
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, dGTP pyrophosphohydrolase
Authors:Piton, J, Larue, V, Thillier, Y, Dorleans, A, Pellegrini, O, Li de la Sierra-Gallay, I, Vasseur, J.J, Debart, F, Tisne, C, Condon, C.
Deposit date:2013-04-03
Release date:2013-05-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Bacillus subtilis RNA deprotection enzyme RppH recognizes guanosine in the second position of its substrates.
Proc.Natl.Acad.Sci.USA, 110, 2013
4JZV
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Crystal structure of the Bacillus subtilis pyrophosphohydrolase BsRppH bound to a non-hydrolysable triphosphorylated dinucleotide RNA (pcp-pGpG) - second guanosine residue in guanosine binding pocket
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MAGNESIUM ION, RNA (5'-R(*(GCP)P*G)-3'), ...
Authors:Piton, J, Larue, V, Thillier, Y, Dorleans, A, Pellegrini, O, Li de la Sierra-Gallay, I, Vasseur, J.J, Debart, F, Tisne, C, Condon, C.
Deposit date:2013-04-03
Release date:2013-05-08
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Bacillus subtilis RNA deprotection enzyme RppH recognizes guanosine in the second position of its substrates.
Proc.Natl.Acad.Sci.USA, 110, 2013
4JZS
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BU of 4jzs by Molmil
Crystal structure of the Bacillus subtilis pyrophosphohydrolase BsRppH (E68A mutant)
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, dGTP pyrophosphohydrolase
Authors:Piton, J, Larue, V, Thillier, Y, Dorleans, A, Pellegrini, O, Li de la Sierra-Gallay, I, Vasseur, J.J, Debart, F, Tisne, C, Condon, C.
Deposit date:2013-04-03
Release date:2013-05-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Bacillus subtilis RNA deprotection enzyme RppH recognizes guanosine in the second position of its substrates.
Proc.Natl.Acad.Sci.USA, 110, 2013
4JZU
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BU of 4jzu by Molmil
Crystal structure of the Bacillus subtilis pyrophosphohydrolase BsRppH bound to a non-hydrolysable triphosphorylated dinucleotide RNA (pcp-pGpG) - first guanosine residue in guanosine binding pocket
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, RNA (5'-R(*(GCP)P*G)-3'), RNA PYROPHOSPHOHYDROLASE
Authors:Piton, J, Larue, V, Thillier, Y, Dorleans, A, Pellegrini, O, Li de la Sierra-Gallay, I, Vasseur, J.J, Debart, F, Tisne, C, Condon, C.
Deposit date:2013-04-03
Release date:2013-05-08
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Bacillus subtilis RNA deprotection enzyme RppH recognizes guanosine in the second position of its substrates.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KG4
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BU of 4kg4 by Molmil
Crystal structure of Saccharomyces cerevisiae Dcp2 Nudix domain (E198Q mutation)
Descriptor: mRNA-decapping enzyme subunit 2
Authors:Aglietti, R.A, Floor, S.N, Gross, J.D.
Deposit date:2013-04-28
Release date:2013-08-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Active site conformational dynamics are coupled to catalysis in the mRNA decapping enzyme dcp2.
Structure, 21, 2013
3A6S
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BU of 3a6s by Molmil
Crystal structure of the MutT protein
Descriptor: L(+)-TARTARIC ACID, Mutator mutT protein, SODIUM ION
Authors:Nakamura, T, Yamagata, Y.
Deposit date:2009-09-09
Release date:2009-10-27
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and dynamic features of the MutT protein in the recognition of nucleotides with the mutagenic 8-oxoguanine base
J.Biol.Chem., 285, 2010
3AC9
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BU of 3ac9 by Molmil
Crystal structure of human NUDT5 complexed with 8-oxo-dGDP and manganese
Descriptor: 2'-deoxy-8-oxoguanosine 5'-(trihydrogen diphosphate), ADP-sugar pyrophosphatase, MANGANESE (II) ION
Authors:Arimori, T, Yamagata, Y.
Deposit date:2009-12-30
Release date:2011-01-12
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Diverse substrate recognition and hydrolysis mechanisms of human NUDT5
Nucleic Acids Res., 39, 2011
2YVO
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BU of 2yvo by Molmil
Crystal structure of NDX2 in complex with MG2+ and AMP from thermus thermophilus HB8
Descriptor: ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, MutT/nudix family protein
Authors:Wakamatsu, T, Nakagawa, N, Kuramitsu, S, Yokoyama, S, Masui, R, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-13
Release date:2008-02-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structural basis for different substrate specificities of two ADP-ribose pyrophosphatases from Thermus thermophilus HB8
J.Bacteriol., 190, 2008
4K6E
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BU of 4k6e by Molmil
Crystal structure of Saccharomyces cerevisiae Dcp2 Nudix domain in complex with Mg
Descriptor: MAGNESIUM ION, mRNA-decapping enzyme subunit 2
Authors:Aglietti, R.A, Floor, S.N, Gross, J.D.
Deposit date:2013-04-15
Release date:2013-08-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Active site conformational dynamics are coupled to catalysis in the mRNA decapping enzyme dcp2.
Structure, 21, 2013
4KG3
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BU of 4kg3 by Molmil
Crystal structure of Saccharomyces cerevisiae Dcp2 Nudix domain in complex with Mg (E153Q mutation)
Descriptor: MAGNESIUM ION, mRNA-decapping enzyme subunit 2
Authors:Aglietti, R.A, Floor, S.N, Gross, J.D.
Deposit date:2013-04-28
Release date:2013-08-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Active site conformational dynamics are coupled to catalysis in the mRNA decapping enzyme dcp2.
Structure, 21, 2013
4KYX
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BU of 4kyx by Molmil
Crystal structure of ADP-ribose pyrophosphatase MutT from Rickettsia felis
Descriptor: ADP-ribose pyrophosphatase MutT
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2013-05-29
Release date:2013-08-07
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of ADP-ribose pyrophosphatase MutT from Rickettsia felis
To be Published
3ACA
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BU of 3aca by Molmil
Crystal structure of human NUDT5 complexed with 8-oxo-dADP and manganese
Descriptor: 8-oxo-7,8-dihydro-2'-deoxy-adenosine-5'-diphosphate, ADP-sugar pyrophosphatase, MANGANESE (II) ION
Authors:Arimori, T, Yamagata, Y.
Deposit date:2009-12-30
Release date:2011-01-12
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Diverse substrate recognition and hydrolysis mechanisms of human NUDT5
Nucleic Acids Res., 39, 2011
3A6U
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BU of 3a6u by Molmil
Crystal structure of MutT-8-OXO-dGMP-MN(II) complex
Descriptor: 8-OXO-2'-DEOXY-GUANOSINE-5'-MONOPHOSPHATE, MANGANESE (II) ION, Mutator mutT protein, ...
Authors:Nakamura, T, Yamagata, Y.
Deposit date:2009-09-09
Release date:2009-10-27
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Structural and dynamic features of the MutT protein in the recognition of nucleotides with the mutagenic 8-oxoguanine base
J.Biol.Chem., 285, 2010
4ICK
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BU of 4ick by Molmil
Crystal structure of human AP4A hydrolase E58A mutant
Descriptor: Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical], GLYCEROL, MAGNESIUM ION, ...
Authors:Ge, H, Chen, X.
Deposit date:2012-12-10
Release date:2013-12-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of wild-type and mutant human Ap4A hydrolase.
Biochem.Biophys.Res.Commun., 432, 2013
3BM4
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BU of 3bm4 by Molmil
Crystal Structure of Human ADP-ribose Pyrophosphatase NUDT5 In complex with magnesium and AMPcpr
Descriptor: ADP-sugar pyrophosphatase, ALPHA-BETA METHYLENE ADP-RIBOSE, MAGNESIUM ION
Authors:Zha, M, Guo, Q, Zhang, Y, Zhong, C, Ou, Y, Ding, J.
Deposit date:2007-12-12
Release date:2008-05-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular Mechanism of ADP-Ribose Hydrolysis By Human NUDT5 From Structural and Kinetic Studies
J.Mol.Biol., 379, 2008
4IJX
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BU of 4ijx by Molmil
Crystal structure of human Ap4A hydrolase E58A mutant complexed with DPO
Descriptor: Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical], DIPHOSPHATE, GLYCEROL, ...
Authors:Ge, H, Chen, X.
Deposit date:2012-12-24
Release date:2013-03-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of wild-type and mutant human Ap4A hydrolase.
Biochem.Biophys.Res.Commun., 432, 2013
4ILQ
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BU of 4ilq by Molmil
2.60A resolution structure of CT771 from Chlamydia trachomatis
Descriptor: CT771, GLYCEROL, SULFATE ION
Authors:Barta, M.L, Lovell, S, Battaile, K.P, Hefty, P.S.
Deposit date:2012-12-31
Release date:2014-01-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Chlamydia trachomatis CT771 (nudH) Is an Asymmetric Ap4A Hydrolase.
Biochemistry, 53, 2014
5MP0
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BU of 5mp0 by Molmil
Human m7GpppN-mRNA Hydrolase (DCP2, NUDT20) Catalytic Domain
Descriptor: 1,2-ETHANEDIOL, m7GpppN-mRNA hydrolase
Authors:Mathea, S, Salah, E, Velupillai, S, Tallant, C, Pike, A.C.W, Bushell, S.R, Faust, B, Wang, D, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Huber, K.
Deposit date:2016-12-15
Release date:2017-06-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Human m7GpppN-mRNA Hydrolase (DCP2, NUDT20) Catalytic Domain
To Be Published

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