3AC9

Crystal structure of human NUDT5 complexed with 8-oxo-dGDP and manganese

Summary for 3AC9

Entry DOI	10.2210/pdb3ac9/pdb
Related	3ACA 3L85
Descriptor	ADP-sugar pyrophosphatase, 2'-deoxy-8-oxoguanosine 5'-(trihydrogen diphosphate), MANGANESE (II) ION, ... (4 entities in total)
Functional Keywords	nudix motif, magnesium, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	44283.46
Authors	Arimori, T.,Yamagata, Y. (deposition date: 2009-12-30, release date: 2011-01-12, Last modification date: 2023-11-01)
Primary citation	Arimori, T.,Tamaoki, H.,Nakamura, T.,Kamiya, H.,Ikemizu, S.,Takagi, Y.,Ishibashi, T.,Harashima, H.,Sekiguchi, M.,Yamagata, Y. Diverse substrate recognition and hydrolysis mechanisms of human NUDT5 Nucleic Acids Res., 39:8972-8983, 2011 Cited by PubMed: 21768126 DOI: 10.1093/nar/gkr575 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation