8HY9
| Bacterial STING from Riemerella anatipestifer in complex with 3'3'-c-di-GMP | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION, CD-NTase-associated protein 12 | Authors: | Wang, Y.-C, Yang, C.-S, Hou, M.-H, Chen, Y. | Deposit date: | 2023-01-06 | Release date: | 2024-01-10 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.462 Å) | Cite: | Structural insights into the regulation, ligand recognition, and oligomerization of bacterial STING. Nat Commun, 14, 2023
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6LOV
| crystal structure of alpha-momorcharin in complex with xanthosine | Descriptor: | 2,3-dihydroxanthosine, Ribosome-inactivating protein momordin I | Authors: | Fan, X, Jin, T. | Deposit date: | 2020-01-07 | Release date: | 2020-11-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Atomic-resolution structures of type I ribosome inactivating protein alpha-momorcharin with different substrate analogs. Int.J.Biol.Macromol., 164, 2020
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6MG0
| Crystal structure of a 5-domain construct of LgrA in the thiolation state | Descriptor: | 5'-({[(2R,3R)-3-amino-2-{[2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-{[oxido(oxo)phosphonio]oxy}butanoyl]-beta-alanyl}amino)ethyl]sulfanyl}-4-methylpentyl]sulfonyl}amino)-5'-deoxyadenosine, Linear gramicidin synthase subunit A | Authors: | Reimer, J.M, Eivaskhani, M, Harb, I, Schmeing, T.M. | Deposit date: | 2018-09-12 | Release date: | 2019-11-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (6 Å) | Cite: | Structures of a dimodular nonribosomal peptide synthetase reveal conformational flexibility. Science, 366, 2019
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3AN1
| Crystal structure of rat D428A mutant, urate bound form | Descriptor: | BICARBONATE ION, CALCIUM ION, FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Okamoto, K, Kawaguchi, Y, Eger, B.T, Pai, E.F, Nishino, T. | Deposit date: | 2010-08-27 | Release date: | 2010-12-01 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Crystal Structures of Urate Bound Form of Xanthine Oxidoreductase: Substrate Orientation and Structure of the Key Reaction Intermediate J.Am.Chem.Soc., 132, 2010
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8QTY
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8IOO
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6OPI
| phosphorylated ERK2 with SCH-CPD336 | Descriptor: | (3R)-N-[3-(2-cyclopropylpyridin-4-yl)-1H-indazol-5-yl]-3-(methoxymethyl)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]-3,6-dihydropyridin-1(2H)-yl}ethyl)pyrrolidine-3-carboxamide, Mitogen-activated protein kinase 1 | Authors: | Vigers, G.P, Smith, D. | Deposit date: | 2019-04-25 | Release date: | 2019-07-31 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Activation loop dynamics are controlled by conformation-selective inhibitors of ERK2. Proc.Natl.Acad.Sci.USA, 116, 2019
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3ANO
| Crystal Structure of a Novel Diadenosine 5',5'''-P1,P4-Tetraphosphate Phosphorylase from Mycobacterium tuberculosis H37Rv | Descriptor: | AP-4-A phosphorylase, PHOSPHATE ION, TETRAETHYLENE GLYCOL | Authors: | Mori, S, Shibayama, K, Wachino, J, Arakawa, Y. | Deposit date: | 2010-09-06 | Release date: | 2011-05-18 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.894 Å) | Cite: | Structural insights into the novel diadenosine 5',5-P1,P4-tetraphosphate phosphorylase from Mycobacterium tuberculosis H37Rv J.Mol.Biol., 410, 2011
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3BAC
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3BBP
| Rab6-GTP:GCC185 Rab binding domain complex | Descriptor: | GRIP and coiled-coil domain-containing protein 2, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Schweizer Burguete, A, Fenn, T.D, Brunger, A.T, Pfeffer, S.R. | Deposit date: | 2007-11-09 | Release date: | 2008-02-05 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Rab and Arl GTPase family members cooperate in the localization of the golgin GCC185. Cell(Cambridge,Mass.), 132, 2008
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2Z7R
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3C9U
| AaThiL complexed with ADP and TPP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, THIAMINE DIPHOSPHATE, ... | Authors: | McCulloch, K.M, Kinsland, C, Begley, T.P, Ealick, S.E. | Deposit date: | 2008-02-18 | Release date: | 2008-03-18 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Structural studies of thiamin monophosphate kinase in complex with substrates and products. Biochemistry, 47, 2008
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7LY5
| Proteolyzed crystal structure of the bacillamide NRPS, BmdB, in complex with the oxidase BmdC | Descriptor: | BmdB, Bacillamide NRPS, BmdC, ... | Authors: | Fortinez, C.M, Schmeing, T.M. | Deposit date: | 2021-03-05 | Release date: | 2022-02-02 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structures and function of a tailoring oxidase in complex with a nonribosomal peptide synthetase module. Nat Commun, 13, 2022
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7LY7
| Crystal structure of the elongation module of the bacillamide NRPS, BmdB, in complex with the oxidase BmdC | Descriptor: | 5'-{[(2R,3S)-3-amino-2-({2-[(N-{(2R)-4-[(dihydroxyphosphanyl)oxy]-2-hydroxy-3,3-dimethylbutanoyl}-beta-alanyl)amino]ethyl}sulfanyl)-4-sulfanylbutane-1-sulfonyl]amino}-5'-deoxyadenosine, BmdB, Bacillamide NRPS, ... | Authors: | Fortinez, C.M, Sharon, I, Schmeing, T.M. | Deposit date: | 2021-03-05 | Release date: | 2022-02-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Structures and function of a tailoring oxidase in complex with a nonribosomal peptide synthetase module. Nat Commun, 13, 2022
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5VJP
| Crystal Structure of Adenine Phosphoribosyltransferase from Saccharomyces cerevisiae Complexed with L-2,5-Dideoxy-2,5-Imino-Altritol 1,6-Bisphosphate (L-DIAB) and Adenine | Descriptor: | 1,2-ETHANEDIOL, ADENINE, Adenine phosphoribosyltransferase 1, ... | Authors: | Harijan, R.K, Ducati, R.G, Bonanno, J.B, Almo, S.C, Schramm, V.L. | Deposit date: | 2017-04-19 | Release date: | 2017-12-27 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Synthesis of bis-Phosphate Iminoaltritol Enantiomers and Structural Characterization with Adenine Phosphoribosyltransferase. ACS Chem. Biol., 13, 2018
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5VJN
| Crystal Structure of Adenine Phosphoribosyltransferase from Saccharomyces cerevisiae Complexed with D-2,5-Dideoxy-2,5-Imino-Altritol 1,6-Bisphosphate (D-DIAB) and Adenine | Descriptor: | 1,2-ETHANEDIOL, ADENINE, Adenine phosphoribosyltransferase 1, ... | Authors: | Harijan, R.K, Ducati, R.G, Bonanno, J.B, Almo, S.C, Schramm, V.L. | Deposit date: | 2017-04-19 | Release date: | 2017-12-27 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Synthesis of bis-Phosphate Iminoaltritol Enantiomers and Structural Characterization with Adenine Phosphoribosyltransferase. ACS Chem. Biol., 13, 2018
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6P1J
| The structure of condensation and adenylation domains of teixobactin-producing nonribosomal peptide synthetase Txo2 serine module | Descriptor: | ACETATE ION, CHLORIDE ION, CITRATE ANION, ... | Authors: | Tan, K, Zhou, M, Jedrzejczak, R, Babnigg, G, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2019-05-20 | Release date: | 2019-05-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structures of teixobactin-producing nonribosomal peptide synthetase condensation and adenylation domains. Curr Res Struct Biol, 2, 2020
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6IMK
| The crystal structure of AsfvLIG:CG complex | Descriptor: | DNA (5'-D(*CP*CP*AP*GP*TP*CP*CP*GP*AP*CP*CP*CP*GP*CP*AP*TP*CP*CP*CP*GP*GP*A)-3'), DNA (5'-D(*TP*CP*CP*GP*GP*GP*AP*TP*GP*CP*GP*G)-3'), DNA (5'-D(P*GP*TP*CP*GP*GP*AP*CP*TP*GP*G)-3'), ... | Authors: | Chen, Y.Q, Gan, J.H. | Deposit date: | 2018-10-23 | Release date: | 2019-02-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.502 Å) | Cite: | Structure of the error-prone DNA ligase of African swine fever virus identifies critical active site residues. Nat Commun, 10, 2019
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6IMN
| The crystal structure of AsfvLIG:CT2 complex | Descriptor: | CHLORIDE ION, DNA (5'-D(*CP*CP*AP*GP*TP*CP*CP*GP*AP*CP*CP*CP*GP*CP*AP*TP*CP*CP*CP*GP*GP*A)-3'), DNA (5'-D(*TP*CP*CP*GP*GP*GP*AP*TP*GP*CP*GP*TP*GP*TP*CP*GP*GP*AP*CP*TP*GP*G)-3'), ... | Authors: | Chen, Y.Q, Gan, J.H. | Deposit date: | 2018-10-23 | Release date: | 2019-02-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of the error-prone DNA ligase of African swine fever virus identifies critical active site residues. Nat Commun, 10, 2019
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6IML
| The crystal structure of AsfvLIG:CT1 complex | Descriptor: | DNA (5'-D(*CP*CP*AP*GP*TP*CP*CP*GP*AP*CP*CP*CP*GP*CP*AP*TP*CP*CP*CP*GP*GP*A)-3'), DNA (5'-D(*TP*CP*CP*GP*GP*GP*AP*TP*GP*CP*GP*T)-3'), DNA (5'-D(P*GP*TP*CP*GP*GP*AP*CP*TP*GP*G)-3'), ... | Authors: | Chen, Y.Q, Gan, J.H. | Deposit date: | 2018-10-23 | Release date: | 2019-02-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structure of the error-prone DNA ligase of African swine fever virus identifies critical active site residues. Nat Commun, 10, 2019
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6PZP
| Crystal structure of caspase-1 in complex with VX-765 | Descriptor: | Caspase-1, N-(4-amino-3-chlorobenzene-1-carbonyl)-3-methyl-L-valyl-N-[(2S)-1-carboxy-3-oxopropan-2-yl]-L-prolinamide | Authors: | Yang, J, Liu, Z, Xiao, T.S. | Deposit date: | 2019-08-01 | Release date: | 2020-08-05 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Crystal structure of caspase-1 in complex with VX-765 To Be Published
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6IMJ
| The crystal structure of Se-AsfvLIG:DNA complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CADMIUM ION, CHLORIDE ION, ... | Authors: | Chen, Y.Q, Gan, J.H. | Deposit date: | 2018-10-23 | Release date: | 2019-02-27 | Method: | X-RAY DIFFRACTION (2.554 Å) | Cite: | Structure of the error-prone DNA ligase of African swine fever virus identifies critical active site residues. Nat Commun, 10, 2019
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6Q2M
| Crystal structure of Photinus pyralis Luciferase Pps6 mutant in complex with DLSA | Descriptor: | (2S,5S)-hexane-2,5-diol, 1,2-ETHANEDIOL, 5'-O-[N-(DEHYDROLUCIFERYL)-SULFAMOYL] ADENOSINE, ... | Authors: | Patel, K.D, Gulick, A.M. | Deposit date: | 2019-08-08 | Release date: | 2019-10-16 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Mutagenesis and Structural Studies Reveal the Basis for the Activity and Stability Properties That Distinguish thePhotinusLuciferasesscintillansandpyralis. Biochemistry, 58, 2019
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6JP9
| Crsytal structure of a XMP complexed ATPPase subunit of M. jannaschii GMP synthetase | Descriptor: | GMP synthase [glutamine-hydrolyzing] subunit B, MALONIC ACID, TRIETHYLENE GLYCOL, ... | Authors: | Shivakumarasamy, S, Balaram, H. | Deposit date: | 2019-03-26 | Release date: | 2020-04-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Mechanistic Insights into the Functioning of a Two-Subunit GMP Synthetase, an Allosterically Regulated, Ammonia Channeling Enzyme. Biochemistry, 61, 2022
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6I8V
| KtrC with ATP bound | Descriptor: | 1,4-BUTANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ... | Authors: | Rocha, R, Morais-Cabral, J.H. | Deposit date: | 2018-11-21 | Release date: | 2019-10-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.991 Å) | Cite: | Characterization of the molecular properties of KtrC, a second RCK domain that regulates a Ktr channel in Bacillus subtilis. J.Struct.Biol., 205, 2019
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