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5JJ6
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BU of 5jj6 by Molmil
Fic-1 (aa134 - 508) from C. elegans
Descriptor: Adenosine monophosphate-protein transferase FICD homolog, SULFATE ION
Authors:Cruz, V.E, Schwartz, T.U.
Deposit date:2016-04-22
Release date:2016-06-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.907 Å)
Cite:Fic-1 dimer
To be published
5JEM
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BU of 5jem by Molmil
Complex of IRF-3 with CBP
Descriptor: CREB-binding protein, Interferon regulatory factor 3
Authors:Zhao, B, Li, P.
Deposit date:2016-04-18
Release date:2016-06-15
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for concerted recruitment and activation of IRF-3 by innate immune adaptor proteins.
Proc.Natl.Acad.Sci.USA, 113, 2016
2GQ1
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BU of 2gq1 by Molmil
Crystal Structure of Recombinant Type I Fructose-1,6-bisphosphatase from Escherichia coli Complexed with Sulfate Ions
Descriptor: Fructose-1,6-bisphosphatase, SULFATE ION
Authors:Hines, J.K, Fromm, H.J, Honzatko, R.B.
Deposit date:2006-04-19
Release date:2006-05-02
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Novel Allosteric Activation Site in Escherichia coli Fructose-1,6-bisphosphatase.
J.Biol.Chem., 281, 2006
6EGD
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BU of 6egd by Molmil
Crystal structure of the unphosphorylated IRAK4 kinase domain Bound to a type I inhibitor
Descriptor: Interleukin-1 receptor-associated kinase 4, N-[2-methoxy-4-(morpholin-4-yl)phenyl]-2-(pyridin-3-yl)-1,3-thiazole-5-carboxamide
Authors:Ferrao, R, Wu, H.
Deposit date:2018-08-19
Release date:2019-02-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Conformational flexibility and inhibitor binding to unphosphorylated interleukin-1 receptor-associated kinase 4 (IRAK4).
J.Biol.Chem., 294, 2019
5JER
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BU of 5jer by Molmil
Structure of Rotavirus NSP1 bound to IRF-3
Descriptor: Interferon regulatory factor 3, Rotavirus NSP1 peptide
Authors:Zhao, B, Li, P.
Deposit date:2016-04-18
Release date:2016-06-15
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.913 Å)
Cite:Structural basis for concerted recruitment and activation of IRF-3 by innate immune adaptor proteins.
Proc.Natl.Acad.Sci.USA, 113, 2016
5JEJ
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BU of 5jej by Molmil
Phosphorylated STING in complex with IRF-3 CTD
Descriptor: Interferon regulatory factor 3, Stimulator of interferon genes protein
Authors:Li, P, Shu, C.
Deposit date:2016-04-18
Release date:2016-06-15
Last modified:2016-06-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for concerted recruitment and activation of IRF-3 by innate immune adaptor proteins.
Proc.Natl.Acad.Sci.USA, 113, 2016
1YXX
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BU of 1yxx by Molmil
Crystal Structure of Kinase Pim1 in complex with (3E)-3-[(4-HYDROXYPHENYL)IMINO]-1H-INDOL-2(3H)-ONE
Descriptor: (3E)-3-[(4-HYDROXYPHENYL)IMINO]-1H-INDOL-2(3H)-ONE, IMIDAZOLE, Proto-oncogene serine/threonine-protein kinase Pim-1
Authors:Kumar, A, Mandiyan, V, Suzuki, Y, Zhang, C, Rice, J, Tsai, J, Artis, D.R, Ibrahim, P, Bremer, R.
Deposit date:2005-02-22
Release date:2005-04-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of proto-oncogene kinase Pim1: a target of aberrant somatic hypermutations in diffuse large cell lymphoma.
J.Mol.Biol., 348, 2005
1YWV
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BU of 1ywv by Molmil
Crystal Structures of Proto-Oncogene Kinase Pim1: a Target of Aberrant Somatic Hypermutations in Diffuse Large Cell Lymphoma
Descriptor: IMIDAZOLE, Proto-oncogene serine/threonine-protein kinase Pim-1
Authors:Kumar, A, Mandiyan, V, Suzuki, Y, Zhang, C, Rice, J, Tsai, J, Artis, D.R, Ibrahim, P, Bremer, R.
Deposit date:2005-02-18
Release date:2005-04-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of proto-oncogene kinase Pim1: a target of aberrant somatic hypermutations in diffuse large cell lymphoma.
J.Mol.Biol., 348, 2005
1YXV
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BU of 1yxv by Molmil
Crystal Structure of Kinase Pim1 in complex with 3,4-Dihydroxy-1-methylquinolin-2(1H)-one
Descriptor: 3,4-DIHYDROXY-1-METHYLQUINOLIN-2(1H)-ONE, IMIDAZOLE, Proto-oncogene serine/threonine-protein kinase Pim-1
Authors:Kumar, A, Mandiyan, V, Suzuki, Y, Zhang, C, Rice, J, Tsai, J, Artis, D.R, Ibrahim, P, Bremer, R.
Deposit date:2005-02-22
Release date:2005-04-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of Proto-oncogene Kinase Pim1: A Target of Aberrant Somatic Hypermutations in Diffuse Large Cell Lymphoma.
J.Mol.Biol., 348, 2005
1YXS
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BU of 1yxs by Molmil
Crystal Structure of Kinase Pim1 with P123M mutation
Descriptor: IMIDAZOLE, Proto-oncogene serine/threonine-protein kinase Pim-1
Authors:Kumar, A, Mandiyan, V, Suzuki, Y, Zhang, C, Rice, J, Tsai, J, Artis, D.R, Ibrahim, P, Bremer, R.
Deposit date:2005-02-22
Release date:2005-04-26
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of proto-oncogene kinase Pim1: a target of aberrant somatic hypermutations in diffuse large cell lymphoma.
J.Mol.Biol., 348, 2005
3GYX
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BU of 3gyx by Molmil
Crystal structure of adenylylsulfate reductase from Desulfovibrio gigas
Descriptor: Adenylylsulfate Reductase, FLAVIN-ADENINE DINUCLEOTIDE, IRON/SULFUR CLUSTER
Authors:Chiang, Y.-L, Hsieh, Y.-C, Liu, E.-H, Liu, M.-Y, Chen, C.-J.
Deposit date:2009-04-06
Release date:2009-12-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of Adenylylsulfate reductase from Desulfovibrio gigas suggests a potential self-regulation mechanism involving the C terminus of the beta-subunit
J.Bacteriol., 191, 2009
7XZH
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BU of 7xzh by Molmil
Cryo-EM structure of human LRRC8A
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHOLESTEROL, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine, ...
Authors:Liu, H, Liao, J.
Deposit date:2022-06-02
Release date:2023-06-07
Method:ELECTRON MICROSCOPY (2.78 Å)
Cite:cryo-EM structure of human LRRC8A
To Be Published
7JSN
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BU of 7jsn by Molmil
Structure of the Visual Signaling Complex between Transducin and Phosphodiesterase 6
Descriptor: 2-{2-ETHOXY-5-[(4-ETHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-5-METHYL-7-PROPYLIMIDAZO[5,1-F][1,2,4]TRIAZIN-4(1H)-ONE, GUANOSINE-3',5'-MONOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Gao, Y, Eskici, G, Ramachandran, S, Skiniotis, G, Cerione, R.A.
Deposit date:2020-08-15
Release date:2020-10-21
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of the Visual Signaling Complex between Transducin and Phosphodiesterase 6.
Mol.Cell, 80, 2020
2ZT7
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BU of 2zt7 by Molmil
Crystal structure of human Glycyl-tRNA synthetase (GlyRS) in complex with Glycine and ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GLYCINE, Glycyl-tRNA synthetase
Authors:Guo, R.T, Yang, X.L, Schimmel, P.
Deposit date:2008-09-19
Release date:2009-08-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures and biochemical analyses suggest unique mechanism and role for human GlyRS in Ap4A homeostasis
To be Published
2ZT5
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BU of 2zt5 by Molmil
Crystal structure of human glycyl-trna synthetase (GLYRS) in complex with AP4A (cocrystallized with ATP)
Descriptor: BIS(ADENOSINE)-5'-TETRAPHOSPHATE, Glycyl-tRNA synthetase
Authors:Guo, R.T, Yang, X.L, Schimmel, P.
Deposit date:2008-09-19
Release date:2009-08-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures and biochemical analyses suggest unique mechanism and role for human GlyRS in Ap4A homeostasis
To be Published
6O6E
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BU of 6o6e by Molmil
Crystal structure of PltF trapped with PltL using a proline adenosine vinylsulfonamide inhibitor
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-deoxy-5'-({(2S)-2-({2-[(N-{(2R)-4-[(dioxo-lambda~5~-phosphanyl)oxy]-2-hydroxy-3,3-dimethylbutanoyl}-beta-alanyl)amino]ethyl}sulfanyl)-2-[(2S)-pyrrolidin-2-yl]ethanesulfonyl}amino)adenosine, FORMIC ACID, ...
Authors:Corpuz, J.C, Podust, L.M.
Deposit date:2019-03-06
Release date:2020-04-08
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Dynamic visualization of type II peptidyl carrier protein recognition in pyoluteorin biosynthesis.
Rsc Chem Biol, 1, 2020
7C9A
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BU of 7c9a by Molmil
Human RAD51 post-synaptic complexes mutant (V273P, D274G)
Descriptor: CALCIUM ION, DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), ...
Authors:Chi, H.Y, Ho, M.C, Tsai, M.D, Luo, S.C, Yeh, H.Y.
Deposit date:2020-06-05
Release date:2020-11-18
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:Identification of fidelity-governing factors in human recombinases DMC1 and RAD51 from cryo-EM structures.
Nat Commun, 12, 2021
8B41
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BU of 8b41 by Molmil
Structure of heteromeric LRRC8A/C (1:1 co-transfected) Volume-Regulated Anion Channel in complex with synthetic nanobody Sb1
Descriptor: Synthetic nanobody Sb1, Volume-regulated anion channel subunit LRRC8A, Volume-regulated anion channel subunit LRRC8C
Authors:Sawicka, M, Dutzler, R.
Deposit date:2022-09-19
Release date:2022-12-14
Last modified:2023-02-01
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of a volume-regulated heteromeric LRRC8A/C channel.
Nat.Struct.Mol.Biol., 30, 2023
5WX9
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BU of 5wx9 by Molmil
Crystal Structure of AtERF96 with GCC-box
Descriptor: Ethylene-responsive transcription factor ERF096, GCC-box motif
Authors:Chen, C.Y, Cheng, Y.S.
Deposit date:2017-01-06
Release date:2017-11-22
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structural insights into Arabidopsis ethylene response factor 96 with an extended N-terminal binding to GCC box.
Plant Mol.Biol., 104, 2020
2JR8
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BU of 2jr8 by Molmil
Solution structure of Manduca sexta moricin
Descriptor: Antimicrobial peptide moricin
Authors:Gong, Y, Dai, H, Rayaprolu, S, Huang, R, Prakash, O, Jiang, H.
Deposit date:2007-06-21
Release date:2008-03-25
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:Solution structure, antibacterial activity, and expression profile of Manduca sexta moricin.
J.Pept.Sci., 14, 2008
9B56
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BU of 9b56 by Molmil
Ubiquitin E2-Ub-E3 HECT tetrahedral transthiolation intermediate mimic - state 2
Descriptor: 4-aminobutanenitrile, E3 ubiquitin-protein ligase pub2, Ubiquitin, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-04
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 2024
9B5B
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BU of 9b5b by Molmil
Ubiquitin E2-Ub-E3 HECT tetrahedral transthiolation intermediate mimic - state 7
Descriptor: 4-aminobutanenitrile, E3 ubiquitin-protein ligase pub2, Ubiquitin, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-04
Method:ELECTRON MICROSCOPY (3.31 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 2024
9B5M
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BU of 9b5m by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - consensus map and model
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-04
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 2024
9B5V
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BU of 9b5v by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - Ub(T) class 10 map and model from cluster 1 (ATP/Mg)
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-04
Method:ELECTRON MICROSCOPY (3.94 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 2024
9B5O
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BU of 9b5o by Molmil
Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) - Ub(T) class 10 map and model from consensus
Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kochanczyk, T, Lima, C.D.
Deposit date:2024-03-22
Release date:2024-06-05
Last modified:2024-09-04
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Structural basis for transthiolation intermediates in the ubiquitin pathway.
Nature, 2024

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PDB entries from 2024-09-04

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