5JEJ

Phosphorylated STING in complex with IRF-3 CTD

Summary for 5JEJ

• Entry DOI: 10.2210/pdb5jej/pdb
• Related: 5JEK 5JEL 5JEM 5JEO 5JER
• Descriptor: Stimulator of interferon genes protein, Interferon regulatory factor 3 (3 entities in total)
• Functional Keywords: innate immunity, signaling, immune system
• Biological source: Homo sapiens (Human); More
• Cellular location: Endoplasmic reticulum membrane ; Multi- pass membrane protein : Q86WV6; Cytoplasm : Q14653
• Total number of polymer chains: 5
• Total formula weight: 66539.92

Authors

Li, P.,Shu, C. (deposition date: 2016-04-18, release date: 2016-06-15, Last modification date: 2016-06-29)

• Primary citation: Zhao, B.,Shu, C.,Gao, X.,Sankaran, B.,Du, F.,Shelton, C.L.,Herr, A.B.,Ji, J.Y.,Li, P.; Structural basis for concerted recruitment and activation of IRF-3 by innate immune adaptor proteins.; Proc.Natl.Acad.Sci.USA, 113:E3403-E3412, 2016; PubMed: 27302953; DOI: 10.1073/pnas.1603269113

Experimental method

X-RAY DIFFRACTION (2 Å)