5JEJ
Phosphorylated STING in complex with IRF-3 CTD
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (C, D, E) | Stimulator of interferon genes protein | polymer | 39 | 4245.7 | 3 | UniProt (Q86WV6) | Homo sapiens (Human) | hSTING,Endoplasmic reticulum interferon stimulator,ERIS,Mediator of IRF3 activation,hMITA,Transmembrane protein 173 |
| 2 | D, E (A, B) | Interferon regulatory factor 3 | polymer | 242 | 26901.4 | 2 | UniProt (Q14653) Pfam (PF10401) | Homo sapiens (Human) | IRF-3 |
| 3 | F, G, H, I, J (C, D, E, A, B) | water | water | 18.0 | 380 | Chemie (HOH) |
Sequence modifications
C, D, E: 342 - 379 (UniProt: Q86WV6)
A, B: 189 - 427 (UniProt: Q14653)
| PDB | External Database | Details |
|---|---|---|
| Ser 341 | - | expression tag |
| Trp 378 | Phe 378 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ser 186 | - | expression tag |
| Glu 187 | - | expression tag |
| Phe 188 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 66539.9 | |
| All* | Total formula weight | 66539.9 |
