8HXX
| Cryo-EM structure of the histone deacetylase complex Rpd3S | Descriptor: | Chromatin modification-related protein EAF3, Histone H3, Histone deacetylase RPD3, ... | Authors: | Cui, H, Wang, H. | Deposit date: | 2023-01-05 | Release date: | 2023-09-27 | Last modified: | 2024-11-06 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure of histone deacetylase complex Rpd3S bound to nucleosome. Nat.Struct.Mol.Biol., 30, 2023
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4P6Q
| The crystal structure of the Split End protein SHARP adds a new layer of complexity to proteins containing RNA Recognition Motifs | Descriptor: | Msx2-interacting protein, SULFATE ION | Authors: | Arieti, F, Gabus, C, Tambalo, M, Huet, T, Round, A, Thore, S. | Deposit date: | 2014-03-25 | Release date: | 2014-05-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The crystal structure of the Split End protein SHARP adds a new layer of complexity to proteins containing RNA recognition motifs. Nucleic Acids Res., 42, 2014
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6BPH
| Crystal structure of the chromodomain of RBBP1 | Descriptor: | AT-rich interactive domain-containing protein 4A, UNKNOWN ATOM OR ION | Authors: | Liu, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2017-11-23 | Release date: | 2017-12-20 | Last modified: | 2024-11-06 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure of chromo barrel domain of RBBP1. Biochem. Biophys. Res. Commun., 496, 2018
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9JPJ
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4PU8
| Shewanella oneidensis Toxin Antitoxin System Antitoxin Protein HipB Resolution 2.35 | Descriptor: | Toxin-antitoxin system antidote transcriptional repressor Xre family | Authors: | Wen, Y, Behiels, E, Felix, J, Elegheert, J, Vergauwen, B, Devreese, B, Savvides, S. | Deposit date: | 2014-03-12 | Release date: | 2014-08-06 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | The bacterial antitoxin HipB establishes a ternary complex with operator DNA and phosphorylated toxin HipA to regulate bacterial persistence. Nucleic Acids Res., 42, 2014
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4AQ6
| substrate bound homogentisate 1,2-dioxygenase | Descriptor: | 2-(3,6-DIHYDROXYPHENYL)ACETIC ACID, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FE (III) ION, ... | Authors: | Jeoung, J.-H, Lin, T.-Y, Bommer, M, Dobbek, H. | Deposit date: | 2012-04-12 | Release date: | 2013-04-24 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Visualizing the Substrate-, Superoxo-, Alkylperoxo- and Product-Bound States at the Non-Heme Fe(II) Site of Homogentisate Dioxygenase Proc.Natl.Acad.Sci.USA, 110, 2013
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6YC6
| Structure of C. glutamicum GlnK | Descriptor: | 1,2-ETHANEDIOL, PHOSPHATE ION, PII protein | Authors: | Grau, F.C, Muller, Y.A. | Deposit date: | 2020-03-18 | Release date: | 2021-03-24 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of adenylylated and unadenylylated P II protein GlnK from Corynebacterium glutamicum. Acta Crystallogr D Struct Biol, 77, 2021
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6YC7
| Structure of adenylylated C. glutamicum GlnK | Descriptor: | ADENINE ARABINOSE-5'-PHOSPHATE, ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Grau, F.C, Muller, Y.A. | Deposit date: | 2020-03-18 | Release date: | 2021-03-24 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structures of adenylylated and unadenylylated P II protein GlnK from Corynebacterium glutamicum. Acta Crystallogr D Struct Biol, 77, 2021
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9JPK
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3HRY
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9JPL
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2HQ5
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5TZD
| Structure of the WT S. venezulae BldD-(CTD-c-di-GMP)2 assembly intermediate | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DNA-binding protein | Authors: | Schumacher, M. | Deposit date: | 2016-11-21 | Release date: | 2017-04-19 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.749 Å) | Cite: | The Streptomyces master regulator BldD binds c-di-GMP sequentially to create a functional BldD2-(c-di-GMP)4 complex. Nucleic Acids Res., 45, 2017
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6QEC
| DNA binding domain of LUX ARRYTHMO in complex with DNA | Descriptor: | DNA (5'-D(*AP*TP*TP*CP*GP*AP*AP*TP*AP*T*TP*AP*TP*AP*TP*TP*CP*GP*AP*A)-3'), GLYCEROL, Transcription factor LUX | Authors: | Zubieta, C, Nayak, A. | Deposit date: | 2019-01-07 | Release date: | 2020-02-05 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Molecular mechanisms of Evening Complex activity inArabidopsis. Proc.Natl.Acad.Sci.USA, 117, 2020
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7XVA
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4PU3
| Shewanella oneidensis MR-1 Toxin Antitoxin System HipA, HipB and its operator DNA complex (space group P212121) | Descriptor: | Operator DNA, Toxin-antitoxin system antidote transcriptional repressor Xre family, Toxin-antitoxin system toxin HipA family | Authors: | Wen, Y, Behiels, E, Felix, J, Elegheert, J, Vergauwen, B, Devreese, B, Savvides, S. | Deposit date: | 2014-03-12 | Release date: | 2014-08-06 | Last modified: | 2024-11-06 | Method: | X-RAY DIFFRACTION (3.39 Å) | Cite: | The bacterial antitoxin HipB establishes a ternary complex with operator DNA and phosphorylated toxin HipA to regulate bacterial persistence. Nucleic Acids Res., 42, 2014
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4PU4
| Shewanella oneidensis MR-1 Toxin Antitoxin System HipA, HipB and its operator DNA complex (space group P21) | Descriptor: | Operator DNA, Toxin-antitoxin system antidote transcriptional repressor Xre family, Toxin-antitoxin system toxin HipA family | Authors: | Wen, Y, Behiels, E, Felix, J, Elegheert, J, Vergauwen, B, Devreese, B, Savvides, S. | Deposit date: | 2014-03-12 | Release date: | 2014-08-06 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (3.786 Å) | Cite: | The bacterial antitoxin HipB establishes a ternary complex with operator DNA and phosphorylated toxin HipA to regulate bacterial persistence. Nucleic Acids Res., 42, 2014
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4PU7
| Shewanella oneidensis Toxin Antitoxin System Antitoxin Protein HipB Resolution 1.85 | Descriptor: | Toxin-antitoxin system antidote transcriptional repressor Xre family | Authors: | Wen, Y, Behiels, E, Felix, J, Elegheert, J, Vergauwen, B, Devreese, B, Savvides, S. | Deposit date: | 2014-03-12 | Release date: | 2014-08-06 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The bacterial antitoxin HipB establishes a ternary complex with operator DNA and phosphorylated toxin HipA to regulate bacterial persistence. Nucleic Acids Res., 42, 2014
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6EI0
| Cytosolic copper storage protein Csp from Streptomyces lividans: apo form | Descriptor: | Cytosolic copper storage protein (Ccsp), GLYCEROL, SULFATE ION, ... | Authors: | Straw, M.L, Chaplin, A.K, Hough, M.A, Worrall, J.A.R. | Deposit date: | 2017-09-15 | Release date: | 2018-10-10 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.34 Å) | Cite: | A cytosolic copper storage protein provides a second level of copper tolerance in Streptomyces lividans. Metallomics, 10, 2018
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5WWW
| Crystal structure of the KH1 domain of human RNA-binding E3 ubiquitin-protein ligase MEX-3C complex with RNA | Descriptor: | RNA (5'-R(*GP*UP*UP*UP*AP*G)-3'), RNA-binding E3 ubiquitin-protein ligase MEX3C | Authors: | Yang, L, Wang, C, Li, F, Gong, Q. | Deposit date: | 2017-01-05 | Release date: | 2017-08-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.798 Å) | Cite: | The human RNA-binding protein and E3 ligase MEX-3C binds the MEX-3-recognition element (MRE) motif with high affinity J. Biol. Chem., 292, 2017
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5WWZ
| Crystal structure of the KH2 domain of human RNA-binding E3 ubiquitin-protein ligase MEX-3C | Descriptor: | RNA-binding E3 ubiquitin-protein ligase MEX3C, SULFATE ION | Authors: | Yang, L, Wang, C, Li, F, Gong, Q. | Deposit date: | 2017-01-05 | Release date: | 2017-08-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The human RNA-binding protein and E3 ligase MEX-3C binds the MEX-3-recognition element (MRE) motif with high affinity J. Biol. Chem., 292, 2017
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5WWX
| Crystal structure of the KH2 domain of human RNA-binding E3 ubiquitin-protein ligase MEX-3C complex with RNA | Descriptor: | NICKEL (II) ION, RNA (5'-R(P*AP*GP*AP*GP*U)-3'), RNA-binding E3 ubiquitin-protein ligase MEX3C | Authors: | Yang, L, Wang, C, Li, F, Gong, Q. | Deposit date: | 2017-01-05 | Release date: | 2017-08-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The human RNA-binding protein and E3 ligase MEX-3C binds the MEX-3-recognition element (MRE) motif with high affinity J. Biol. Chem., 292, 2017
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6HS0
| EthR2 in complex with compound 5 (BDM71847) | Descriptor: | 1-[(3-chlorophenyl)methyl]piperazine, Probable transcriptional regulatory protein | Authors: | Wintjens, R, Wohlkonig, A, Tanina, A. | Deposit date: | 2018-09-28 | Release date: | 2019-02-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | A fragment-based approach towards the discovery of N-substituted tropinones as inhibitors of Mycobacterium tuberculosis transcriptional regulator EthR2. Eur J Med Chem, 167, 2019
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6HS1
| EthR2 in complex with compound 9 (BDM76060) | Descriptor: | (1~{R},5~{S})-9-[2-(4-chlorophenyl)ethyl]-9-azabicyclo[3.3.1]nonan-3-one, Probable transcriptional regulatory protein | Authors: | Wintjens, R, Wohlkonig, A, Tanina, A. | Deposit date: | 2018-09-28 | Release date: | 2019-02-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | A fragment-based approach towards the discovery of N-substituted tropinones as inhibitors of Mycobacterium tuberculosis transcriptional regulator EthR2. Eur J Med Chem, 167, 2019
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3FD9
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