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8HXX
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BU of 8hxx by Molmil
Cryo-EM structure of the histone deacetylase complex Rpd3S
Descriptor: Chromatin modification-related protein EAF3, Histone H3, Histone deacetylase RPD3, ...
Authors:Cui, H, Wang, H.
Deposit date:2023-01-05
Release date:2023-09-27
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure of histone deacetylase complex Rpd3S bound to nucleosome.
Nat.Struct.Mol.Biol., 30, 2023
4P6Q
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BU of 4p6q by Molmil
The crystal structure of the Split End protein SHARP adds a new layer of complexity to proteins containing RNA Recognition Motifs
Descriptor: Msx2-interacting protein, SULFATE ION
Authors:Arieti, F, Gabus, C, Tambalo, M, Huet, T, Round, A, Thore, S.
Deposit date:2014-03-25
Release date:2014-05-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of the Split End protein SHARP adds a new layer of complexity to proteins containing RNA recognition motifs.
Nucleic Acids Res., 42, 2014
6BPH
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BU of 6bph by Molmil
Crystal structure of the chromodomain of RBBP1
Descriptor: AT-rich interactive domain-containing protein 4A, UNKNOWN ATOM OR ION
Authors:Liu, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2017-11-23
Release date:2017-12-20
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of chromo barrel domain of RBBP1.
Biochem. Biophys. Res. Commun., 496, 2018
9JPJ
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BU of 9jpj by Molmil
Crystal structure of DhdR in complex with DNA
Descriptor: DNA (27-MER), Pyruvate dehydrogenase complex repressor, ZINC ION
Authors:Sun, P, Wang, B.
Deposit date:2024-09-26
Release date:2024-11-06
Method:X-RAY DIFFRACTION (3.72 Å)
Cite:Crystal structure of DhdR inducer binding domain
To Be Published
4PU8
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BU of 4pu8 by Molmil
Shewanella oneidensis Toxin Antitoxin System Antitoxin Protein HipB Resolution 2.35
Descriptor: Toxin-antitoxin system antidote transcriptional repressor Xre family
Authors:Wen, Y, Behiels, E, Felix, J, Elegheert, J, Vergauwen, B, Devreese, B, Savvides, S.
Deposit date:2014-03-12
Release date:2014-08-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The bacterial antitoxin HipB establishes a ternary complex with operator DNA and phosphorylated toxin HipA to regulate bacterial persistence.
Nucleic Acids Res., 42, 2014
4AQ6
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BU of 4aq6 by Molmil
substrate bound homogentisate 1,2-dioxygenase
Descriptor: 2-(3,6-DIHYDROXYPHENYL)ACETIC ACID, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FE (III) ION, ...
Authors:Jeoung, J.-H, Lin, T.-Y, Bommer, M, Dobbek, H.
Deposit date:2012-04-12
Release date:2013-04-24
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Visualizing the Substrate-, Superoxo-, Alkylperoxo- and Product-Bound States at the Non-Heme Fe(II) Site of Homogentisate Dioxygenase
Proc.Natl.Acad.Sci.USA, 110, 2013
6YC6
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BU of 6yc6 by Molmil
Structure of C. glutamicum GlnK
Descriptor: 1,2-ETHANEDIOL, PHOSPHATE ION, PII protein
Authors:Grau, F.C, Muller, Y.A.
Deposit date:2020-03-18
Release date:2021-03-24
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of adenylylated and unadenylylated P II protein GlnK from Corynebacterium glutamicum.
Acta Crystallogr D Struct Biol, 77, 2021
6YC7
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BU of 6yc7 by Molmil
Structure of adenylylated C. glutamicum GlnK
Descriptor: ADENINE ARABINOSE-5'-PHOSPHATE, ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Grau, F.C, Muller, Y.A.
Deposit date:2020-03-18
Release date:2021-03-24
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures of adenylylated and unadenylylated P II protein GlnK from Corynebacterium glutamicum.
Acta Crystallogr D Struct Biol, 77, 2021
9JPK
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BU of 9jpk by Molmil
Crystal structure of DhdR inducer binding domain
Descriptor: Pyruvate dehydrogenase complex repressor, ZINC ION
Authors:Sun, P, Wang, B.
Deposit date:2024-09-26
Release date:2024-11-06
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Crystal structure of DhdR inducer binding domain
To Be Published
3HRY
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BU of 3hry by Molmil
Crystal structure of PHD in a trigonal space group and partially disordered
Descriptor: Prevent host death protein
Authors:Garcia-Pino, A, Loris, R.
Deposit date:2009-06-10
Release date:2010-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Allostery and intrinsic disorder mediate transcription regulation by conditional cooperativity.
Cell(Cambridge,Mass.), 142, 2010
9JPL
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BU of 9jpl by Molmil
Crystal structure of DhdR inducer binding domain in complex with inducer
Descriptor: (2R)-2-hydroxypentanedioic acid, CHLORIDE ION, Pyruvate dehydrogenase complex repressor, ...
Authors:Sun, P, Wang, B.
Deposit date:2024-09-26
Release date:2024-11-06
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Crystal structure of DhdR inducer binding domain
To Be Published
2HQ5
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BU of 2hq5 by Molmil
Crystal structure of multidrug binding protein QacR from Staphylococcus aureus cocrystallized with compound DB359
Descriptor: HTH-type transcriptional regulator qacR, SULFATE ION
Authors:Brooks, B.E, Brennan, R.G.
Deposit date:2006-07-18
Release date:2007-07-17
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Multidrug-Binding Transcription Factor QacR Binds the Bivalent Aromatic Diamidines DB75 and DB359 in Multiple Positions
J.Am.Chem.Soc., 129, 2007
5TZD
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BU of 5tzd by Molmil
Structure of the WT S. venezulae BldD-(CTD-c-di-GMP)2 assembly intermediate
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DNA-binding protein
Authors:Schumacher, M.
Deposit date:2016-11-21
Release date:2017-04-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.749 Å)
Cite:The Streptomyces master regulator BldD binds c-di-GMP sequentially to create a functional BldD2-(c-di-GMP)4 complex.
Nucleic Acids Res., 45, 2017
6QEC
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BU of 6qec by Molmil
DNA binding domain of LUX ARRYTHMO in complex with DNA
Descriptor: DNA (5'-D(*AP*TP*TP*CP*GP*AP*AP*TP*AP*T*TP*AP*TP*AP*TP*TP*CP*GP*AP*A)-3'), GLYCEROL, Transcription factor LUX
Authors:Zubieta, C, Nayak, A.
Deposit date:2019-01-07
Release date:2020-02-05
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular mechanisms of Evening Complex activity inArabidopsis.
Proc.Natl.Acad.Sci.USA, 117, 2020
7XVA
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BU of 7xva by Molmil
Crystal structure of the Human TR4 Ligand Binding Domain in complex with the JAZF1 corepressor fragment
Descriptor: Juxtaposed with another zinc finger protein 1, Nuclear receptor subfamily 2 group C member 2
Authors:Liu, Y, Chen, Z.
Deposit date:2022-05-21
Release date:2022-12-28
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.856 Å)
Cite:Structures of human TR4LBD-JAZF1 and TR4DBD-DNA complexes reveal the molecular basis of transcriptional regulation.
Nucleic Acids Res., 51, 2023
4PU3
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BU of 4pu3 by Molmil
Shewanella oneidensis MR-1 Toxin Antitoxin System HipA, HipB and its operator DNA complex (space group P212121)
Descriptor: Operator DNA, Toxin-antitoxin system antidote transcriptional repressor Xre family, Toxin-antitoxin system toxin HipA family
Authors:Wen, Y, Behiels, E, Felix, J, Elegheert, J, Vergauwen, B, Devreese, B, Savvides, S.
Deposit date:2014-03-12
Release date:2014-08-06
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.39 Å)
Cite:The bacterial antitoxin HipB establishes a ternary complex with operator DNA and phosphorylated toxin HipA to regulate bacterial persistence.
Nucleic Acids Res., 42, 2014
4PU4
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BU of 4pu4 by Molmil
Shewanella oneidensis MR-1 Toxin Antitoxin System HipA, HipB and its operator DNA complex (space group P21)
Descriptor: Operator DNA, Toxin-antitoxin system antidote transcriptional repressor Xre family, Toxin-antitoxin system toxin HipA family
Authors:Wen, Y, Behiels, E, Felix, J, Elegheert, J, Vergauwen, B, Devreese, B, Savvides, S.
Deposit date:2014-03-12
Release date:2014-08-06
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.786 Å)
Cite:The bacterial antitoxin HipB establishes a ternary complex with operator DNA and phosphorylated toxin HipA to regulate bacterial persistence.
Nucleic Acids Res., 42, 2014
4PU7
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BU of 4pu7 by Molmil
Shewanella oneidensis Toxin Antitoxin System Antitoxin Protein HipB Resolution 1.85
Descriptor: Toxin-antitoxin system antidote transcriptional repressor Xre family
Authors:Wen, Y, Behiels, E, Felix, J, Elegheert, J, Vergauwen, B, Devreese, B, Savvides, S.
Deposit date:2014-03-12
Release date:2014-08-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The bacterial antitoxin HipB establishes a ternary complex with operator DNA and phosphorylated toxin HipA to regulate bacterial persistence.
Nucleic Acids Res., 42, 2014
6EI0
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BU of 6ei0 by Molmil
Cytosolic copper storage protein Csp from Streptomyces lividans: apo form
Descriptor: Cytosolic copper storage protein (Ccsp), GLYCEROL, SULFATE ION, ...
Authors:Straw, M.L, Chaplin, A.K, Hough, M.A, Worrall, J.A.R.
Deposit date:2017-09-15
Release date:2018-10-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:A cytosolic copper storage protein provides a second level of copper tolerance in Streptomyces lividans.
Metallomics, 10, 2018
5WWW
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BU of 5www by Molmil
Crystal structure of the KH1 domain of human RNA-binding E3 ubiquitin-protein ligase MEX-3C complex with RNA
Descriptor: RNA (5'-R(*GP*UP*UP*UP*AP*G)-3'), RNA-binding E3 ubiquitin-protein ligase MEX3C
Authors:Yang, L, Wang, C, Li, F, Gong, Q.
Deposit date:2017-01-05
Release date:2017-08-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:The human RNA-binding protein and E3 ligase MEX-3C binds the MEX-3-recognition element (MRE) motif with high affinity
J. Biol. Chem., 292, 2017
5WWZ
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BU of 5wwz by Molmil
Crystal structure of the KH2 domain of human RNA-binding E3 ubiquitin-protein ligase MEX-3C
Descriptor: RNA-binding E3 ubiquitin-protein ligase MEX3C, SULFATE ION
Authors:Yang, L, Wang, C, Li, F, Gong, Q.
Deposit date:2017-01-05
Release date:2017-08-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The human RNA-binding protein and E3 ligase MEX-3C binds the MEX-3-recognition element (MRE) motif with high affinity
J. Biol. Chem., 292, 2017
5WWX
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BU of 5wwx by Molmil
Crystal structure of the KH2 domain of human RNA-binding E3 ubiquitin-protein ligase MEX-3C complex with RNA
Descriptor: NICKEL (II) ION, RNA (5'-R(P*AP*GP*AP*GP*U)-3'), RNA-binding E3 ubiquitin-protein ligase MEX3C
Authors:Yang, L, Wang, C, Li, F, Gong, Q.
Deposit date:2017-01-05
Release date:2017-08-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:The human RNA-binding protein and E3 ligase MEX-3C binds the MEX-3-recognition element (MRE) motif with high affinity
J. Biol. Chem., 292, 2017
6HS0
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BU of 6hs0 by Molmil
EthR2 in complex with compound 5 (BDM71847)
Descriptor: 1-[(3-chlorophenyl)methyl]piperazine, Probable transcriptional regulatory protein
Authors:Wintjens, R, Wohlkonig, A, Tanina, A.
Deposit date:2018-09-28
Release date:2019-02-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:A fragment-based approach towards the discovery of N-substituted tropinones as inhibitors of Mycobacterium tuberculosis transcriptional regulator EthR2.
Eur J Med Chem, 167, 2019
6HS1
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BU of 6hs1 by Molmil
EthR2 in complex with compound 9 (BDM76060)
Descriptor: (1~{R},5~{S})-9-[2-(4-chlorophenyl)ethyl]-9-azabicyclo[3.3.1]nonan-3-one, Probable transcriptional regulatory protein
Authors:Wintjens, R, Wohlkonig, A, Tanina, A.
Deposit date:2018-09-28
Release date:2019-02-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:A fragment-based approach towards the discovery of N-substituted tropinones as inhibitors of Mycobacterium tuberculosis transcriptional regulator EthR2.
Eur J Med Chem, 167, 2019
3FD9
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BU of 3fd9 by Molmil
Crystal Structure of the transcriptional anti-activator ExsD from Pseudomonas aeruginosa
Descriptor: Uncharacterized protein
Authors:Schubot, F.D.
Deposit date:2008-11-25
Release date:2009-06-23
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural evidence suggests that antiactivator ExsD from Pseudomonas aeruginosa is a DNA binding protein
Protein Sci., 18, 2009

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