1VM1
| STRUCTURE OF SHV-1 BETA-LACTAMASE INHIBITED BY TAZOBACTAM | Descriptor: | ACRYLIC ACID, BETA-LACTAMASE SHV-1, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE, ... | Authors: | Kuzin, A.P, Nukaga, M, Nukaga, Y, Hujer, A, Bonomo, R.A, Knox, J.R. | Deposit date: | 2004-08-27 | Release date: | 2004-09-07 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Inhibition of the SHV-1 beta-lactamase by sulfones: crystallographic observation of two reaction intermediates with tazobactam. Biochemistry, 40, 2001
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1W7F
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1WE4
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1WYB
| Structure of 6-aminohexanoate-dimer hydrolase | Descriptor: | 6-aminohexanoate-dimer hydrolase | Authors: | Negoro, S, Ohki, T, Shibata, N, Mizuno, N, Wakitani, Y, Tsurukame, J, Matsumoto, K, Kawamoto, I, Takeo, M, Higuchi, Y. | Deposit date: | 2005-02-09 | Release date: | 2005-09-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of 6-aminohexanoate-dimer hydrolase To be Published
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1WYC
| Structure of 6-aminohexanoate-dimer hydrolase, DN mutant | Descriptor: | 6-aminohexanoate-dimer hydrolase | Authors: | Negoro, S, Ohki, T, Shibata, N, Mizuno, N, Wakitani, Y, Tsurukame, J, Matsumoto, K, Kawamoto, I, Takeo, M, Higuchi, Y. | Deposit date: | 2005-02-09 | Release date: | 2006-02-21 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Nylon-oligomer degrading enzyme/substrate complex: catalytic mechanism of 6-aminohexanoate-dimer hydrolase J.Mol.Biol., 370, 2007
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1XGI
| AmpC beta-lactamase in complex with 3-(3-nitro-phenylsulfamoyl)-thiophene-2-carboxylic acid | Descriptor: | 3-{[(3-NITROANILINE]SULFONYL}THIOPHENE-2-CARBOXYLIC ACID, Beta-lactamase | Authors: | Tondi, D, Morandi, F, Bonnet, R, Costi, M.P, Shoichet, B.K. | Deposit date: | 2004-09-17 | Release date: | 2005-05-03 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Structure-based optimization of a non-beta-lactam lead results in inhibitors that do not up-regulate beta-lactamase expression in cell culture. J.Am.Chem.Soc., 127, 2005
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1XGJ
| AmpC beta-lactamase in complex with 3-(4-carboxy-2-hydroxy-phenylsulfamoyl)-thiophene-2-carboxylic acid | Descriptor: | 3-{[(4-CARBOXY-2-HYDROXYANILINE]SULFONYL}THIOPHENE-2-CARBOXYLIC ACID, Beta-lactamase | Authors: | Tondi, D, Morandi, F, Bonnet, R, Costi, M.P, Shoichet, B.K. | Deposit date: | 2004-09-17 | Release date: | 2005-05-03 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Structure-based optimization of a non-beta-lactam lead results in inhibitors that do not up-regulate beta-lactamase expression in cell culture. J.Am.Chem.Soc., 127, 2005
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1XPB
| STRUCTURE OF BETA-LACTAMASE TEM1 | Descriptor: | BETA-LACTAMASE, SULFATE ION | Authors: | Fonze, E, Charlier, P. | Deposit date: | 1997-01-10 | Release date: | 1997-04-01 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | TEM1 beta-lactamase structure solved by molecular replacement and refined structure of the S235A mutant. Acta Crystallogr.,Sect.D, 51, 1995
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1XX2
| Refinement of P99 beta-lactamase from Enterobacter cloacae | Descriptor: | Beta-lactamase | Authors: | Knox, J.R, Sun, T. | Deposit date: | 2004-11-03 | Release date: | 2004-11-23 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Crystallographic structure of a phosphonate derivative of the Enterobacter cloacae P99 cephalosporinase: mechanistic interpretation of a beta-lactamase transition-state analog. Biochemistry, 33, 1994
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1XXM
| The modular architecture of protein-protein binding site | Descriptor: | Beta-lactamase TEM, Beta-lactamase inhibitory protein, CALCIUM ION | Authors: | Reichmann, D, Rahat, O, Albeck, S, Meged, R, Dym, O, Schreiber, G, Israel Structural Proteomics Center (ISPC) | Deposit date: | 2004-11-07 | Release date: | 2005-01-18 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The modular architecture of protein-protein binding interfaces Proc.Natl.Acad.Sci.USA, 102, 2005
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1Y54
| Crystal structure of the native class C beta-lactamase from Enterobacter cloacae 908R complexed with BRL42715 | Descriptor: | (7R)-6-FORMYL-7-(1-METHYL-1H-1,2,3-TRIAZOL-4-YL)-4,7-DIHYDRO-1,4-THIAZEPINE-3-CARBOXYLIC ACID, Beta-lactamase | Authors: | Michaux, C, Charlier, P, Frere, J.-M, Wouters, J. | Deposit date: | 2004-12-02 | Release date: | 2005-03-29 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure of BRL 42715, C6-(N1-Methyl-1,2,3-triazolylmethylene)penem, in Complex with Enterobactercloacae 908R beta-Lactamase: Evidence for a Stereoselective Mechanism from Docking Studies J.Am.Chem.Soc., 127, 2005
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1YLJ
| Atomic resolution structure of CTX-M-9 beta-lactamase | Descriptor: | SULFATE ION, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, beta-lactamase CTX-M-9a | Authors: | Chen, Y, Delmas, J, Sirot, J, Shoichet, B, Bonnet, R. | Deposit date: | 2005-01-19 | Release date: | 2005-04-19 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (0.98 Å) | Cite: | Atomic Resolution Structures of CTX-M beta-Lactamases: Extended Spectrum Activities from Increased Mobility and Decreased Stability. J.Mol.Biol., 348, 2005
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1YLP
| Atomic resolution structure of CTX-M-27 beta-lactamase | Descriptor: | SULFATE ION, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, beta-lactamase CTX-M-27 | Authors: | Chen, Y, Delmas, J, Sirot, J, Shoichet, B, Bonnet, R. | Deposit date: | 2005-01-19 | Release date: | 2005-04-19 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Atomic Resolution Structures of CTX-M beta-Lactamases: Extended Spectrum Activities from Increased Mobility and Decreased Stability. J.Mol.Biol., 348, 2005
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1YLT
| Atomic resolution structure of CTX-M-14 beta-lactamase | Descriptor: | SULFATE ION, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, beta-lactamase CTX-M-14 | Authors: | Chen, Y, Delmas, J, Sirot, J, Shoichet, B, Bonnet, R. | Deposit date: | 2005-01-19 | Release date: | 2005-04-19 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Atomic Resolution Structures of CTX-M beta-Lactamases: Extended Spectrum Activities from Increased Mobility and Decreased Stability. J.Mol.Biol., 348, 2005
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1YLW
| X-ray structure of CTX-M-16 beta-lactamase | Descriptor: | CTX-M-16 beta-lactamase, SULFATE ION | Authors: | Chen, Y, Delmas, J, Sirot, J, Shoichet, B, Bonnet, R. | Deposit date: | 2005-01-19 | Release date: | 2005-04-19 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Atomic Resolution Structures of CTX-M beta-Lactamases: Extended Spectrum Activities from Increased Mobility and Decreased Stability. J.Mol.Biol., 348, 2005
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1YLY
| X-ray crystallographic structure of CTX-M-9 beta-lactamase complexed with ceftazidime-like boronic acid | Descriptor: | PHOSPHATE ION, PINACOL[[2-AMINO-ALPHA-(1-CARBOXY-1-METHYLETHOXYIMINO)-4-THIAZOLEACETYL]AMINO]METHANEBORONATE, beta-lactamase CTX-M-9 | Authors: | Chen, Y, Shoichet, B, Bonnet, R. | Deposit date: | 2005-01-19 | Release date: | 2005-04-26 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Structure, Function, and Inhibition along the Reaction Coordinate of CTX-M beta-Lactamases. J.Am.Chem.Soc., 127, 2005
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1YLZ
| X-ray crystallographic structure of CTX-M-14 beta-lactamase complexed with ceftazidime-like boronic acid | Descriptor: | BETA-LACTAMASE CTX-M-14, PHOSPHATE ION, PINACOL[[2-AMINO-ALPHA-(1-CARBOXY-1-METHYLETHOXYIMINO)-4-THIAZOLEACETYL]AMINO]METHANEBORONATE | Authors: | Chen, Y, Shoichet, B, Bonnet, R. | Deposit date: | 2005-01-19 | Release date: | 2005-04-26 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Structure, Function, and Inhibition along the Reaction Coordinate of CTX-M beta-Lactamases. J.Am.Chem.Soc., 127, 2005
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1YM1
| X-ray crystallographic structure of CTX-M-9 beta-lactamase complexed with a boronic acid inhibitor (SM2) | Descriptor: | (1R)-1-(2-THIENYLACETYLAMINO)-1-(3-CARBOXYPHENYL)METHYLBORONIC ACID, PHOSPHATE ION, beta-lactamase CTX-M-9a | Authors: | Chen, Y, Shoichet, B, Bonnet, R. | Deposit date: | 2005-01-20 | Release date: | 2005-04-26 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.12 Å) | Cite: | Structure, Function, and Inhibition along the Reaction Coordinate of CTX-M beta-Lactamases. J.Am.Chem.Soc., 127, 2005
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1YMS
| X-ray crystallographic structure of CTX-M-9 beta-lactamase complexed with nafcinin-like boronic acid inhibitor | Descriptor: | [(2-ETHOXY-1-NAPHTHOYL)AMINO]METHYLBORONIC ACID, beta-lactamase CTX-M-9 | Authors: | Chen, Y, Shoichet, B, Bonnet, R. | Deposit date: | 2005-01-21 | Release date: | 2005-04-26 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure, Function, and Inhibition along the Reaction Coordinate of CTX-M beta-Lactamases. J.Am.Chem.Soc., 127, 2005
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1YMX
| X-ray crystallographic structure of CTX-M-9 beta-lactamase covalently linked to cefoxitin | Descriptor: | (2R)-5-[(carbamoyloxy)methyl]-2-{(1S)-1-methoxy-2-oxo-1-[(thiophen-2-ylacetyl)amino]ethyl}-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, beta-lactamase CTX-M-9 | Authors: | Chen, Y, Shoichet, B, Bonnet, R. | Deposit date: | 2005-01-21 | Release date: | 2005-04-26 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure, Function, and Inhibition along the Reaction Coordinate of CTX-M beta-Lactamases. J.Am.Chem.Soc., 127, 2005
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1YQS
| Inhibition of the R61 DD-Peptidase by N-benzoyl-beta-sultam | Descriptor: | 2-(BENZOYLAMINO)ETHANESULFONIC ACID, D-alanyl-D-alanine carboxypeptidase, GLYCEROL | Authors: | Ahmed, N, Cordaro, M, Laws, A.P, Delmarcelle, M, Silvaggi, N.R, Kelly, J.A, Page, M.I. | Deposit date: | 2005-02-02 | Release date: | 2005-06-28 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Inactivation of Bacterial dd-Peptidase by beta-Sultams. Biochemistry, 44, 2005
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1YT4
| Crystal structure of TEM-76 beta-lactamase at 1.4 Angstrom resolution | Descriptor: | Beta-lactamase TEM | Authors: | Thomas, V.L, Golemi-Kotra, D, Kim, C, Vakulenko, S.B, Mobashery, S, Shoichet, B.K. | Deposit date: | 2005-02-09 | Release date: | 2005-07-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural Consequences of the Inhibitor-Resistant Ser130Gly Substitution in TEM beta-Lactamase. Biochemistry, 44, 2005
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1ZC2
| Crystal Structure of plasmid-encoded class C beta-lactamase CMY-2 complexed with citrate molecule | Descriptor: | CITRIC ACID, beta-lactamase class C | Authors: | Bauvois, C, Jacquamet, L, Fieulaine, S, Frere, J.-M, Galleni, M, Ferrer, J.-L. | Deposit date: | 2005-04-10 | Release date: | 2006-04-25 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Crystallographic structure of plasmid-encoded CMY-2 beta-lactamase revealed citrate molecule in the active site. To be Published
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1ZG4
| TEM1 beta lactamase | Descriptor: | Beta-lactamase TEM | Authors: | Stec, B, Holtz, K.M, Wojciechowski, C.L, Kantrowitz, E.R. | Deposit date: | 2005-04-20 | Release date: | 2005-05-17 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structure of the wild-type TEM-1 beta-lactamase at 1.55 A and the mutant enzyme Ser70Ala at 2.1 A suggest the mode of noncovalent catalysis for the mutant enzyme. Acta Crystallogr.,Sect.D, 61, 2005
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1ZG6
| TEM1 beta lactamase mutant S70G | Descriptor: | Beta-lactamase TEM | Authors: | Stec, B, Holtz, K.M, Wojciechowski, C.L, Kantrowitz, E.R. | Deposit date: | 2005-04-20 | Release date: | 2005-05-17 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of the wild-type TEM-1 beta-lactamase at 1.55 A and the mutant enzyme Ser70Ala at 2.1 A suggest the mode of noncovalent catalysis for the mutant enzyme. Acta Crystallogr.,Sect.D, 61, 2005
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