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4YKD
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BU of 4ykd by Molmil
Crystal structure of truncated cerebral cavernous malformation 2 C-terminal adaptor domain
Descriptor: Malcavernin
Authors:Ding, J, Wang, X, Wang, D.C.
Deposit date:2015-03-04
Release date:2015-06-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.932 Å)
Cite:Structural Insights into the Molecular Recognition between Cerebral Cavernous Malformation 2 and Mitogen-Activated Protein Kinase Kinase Kinase 3
Structure, 23, 2015
4YFE
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BU of 4yfe by Molmil
Crystal structure of PTP delta Fn1-Fn2
Descriptor: Receptor-type tyrosine-protein phosphatase delta
Authors:Yamagata, A, Fukai, S.
Deposit date:2015-02-25
Release date:2015-05-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.972 Å)
Cite:Mechanisms of splicing-dependent trans-synaptic adhesion by PTP delta-IL1RAPL1/IL-1RAcP for synaptic differentiation.
Nat Commun, 6, 2015
4YL6
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BU of 4yl6 by Molmil
Crystal structure of truncated cerebral cavernous malformation 2 C-terminal adaptor domain in complex with an internal helix of mitogen-activated protein kinase kinase kinase 3
Descriptor: Malcavernin, Mitogen-activated protein kinase kinase kinase 3
Authors:Ding, J, Wang, X, Wang, D.C.
Deposit date:2015-03-05
Release date:2015-06-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Insights into the Molecular Recognition between Cerebral Cavernous Malformation 2 and Mitogen-Activated Protein Kinase Kinase Kinase 3
Structure, 23, 2015
7BCZ
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BU of 7bcz by Molmil
Structure of the 4'-phosphopantetheinyl transferase PcpS from Pseudomonas aeruginosa
Descriptor: 4'-phosphopantetheinyl transferase EntD, COENZYME A, MAGNESIUM ION, ...
Authors:Carivenc, C, Mourey, L, Pedelacq, J.D.
Deposit date:2020-12-21
Release date:2021-11-10
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Phosphopantetheinyl transferase binding and inhibition by amidino-urea and hydroxypyrimidinethione compounds.
Sci Rep, 11, 2021
4YF2
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BU of 4yf2 by Molmil
Crystal structure of mouse sperm C-type lysozyme-like protein 1
Descriptor: Sperm acrosome membrane-associated protein 3
Authors:Zheng, H, Mandal, A, Shumilin, I.A, Shabalin, I.G, Herr, J.C, Minor, W.
Deposit date:2015-02-24
Release date:2015-03-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Sperm Lysozyme-Like Protein 1 (SLLP1), an intra-acrosomal oolemmal-binding sperm protein, reveals filamentous organization in protein crystal form.
Andrology, 3, 2015
4YFG
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BU of 4yfg by Molmil
Crystal structure of PTP delta meA3/meB minus variant Ig1-Fn1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-type tyrosine-protein phosphatase delta
Authors:Yamagata, A, Fukai, S.
Deposit date:2015-02-25
Release date:2015-05-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.491 Å)
Cite:Mechanisms of splicing-dependent trans-synaptic adhesion by PTP delta-IL1RAPL1/IL-1RAcP for synaptic differentiation.
Nat Commun, 6, 2015
4YGS
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BU of 4ygs by Molmil
Crystal structure of HAD phosphatase from Thermococcus onnurineus
Descriptor: CITRIC ACID, Hydrolase, MAGNESIUM ION
Authors:Ngo, T.D, Le, B.V, Subramani, V.K, Nguyen, C.M.T, Lee, H.S, Cho, Y, Kim, K.K, Hwang, H.Y.
Deposit date:2015-02-26
Release date:2015-04-22
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for the substrate selectivity of a HAD phosphatase from Thermococcus onnurineus NA1
Biochem.Biophys.Res.Commun., 461, 2015
4YH6
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BU of 4yh6 by Molmil
Crystal structure of IL1RAPL1 ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-1 receptor accessory protein-like 1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yamagata, A, Fukai, S.
Deposit date:2015-02-27
Release date:2015-05-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Mechanisms of splicing-dependent trans-synaptic adhesion by PTP delta-IL1RAPL1/IL-1RAcP for synaptic differentiation.
Nat Commun, 6, 2015
3KOH
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BU of 3koh by Molmil
Cytochrome P450 2E1 with omega-imidazolyl octanoic acid
Descriptor: 8-(1H-imidazol-1-yl)octanoic acid, Cytochrome P450 2E1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Scott, E.E, Porubsky, P.R.
Deposit date:2009-11-13
Release date:2010-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Human cytochrome P450 2E1 structures with fatty acid analogs reveal a previously unobserved binding mode.
J.Biol.Chem., 285, 2010
4YFD
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BU of 4yfd by Molmil
Crystal structure PTP delta Ig1-Fn2 in complex with IL-1RAcP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-1 receptor accessory protein, Receptor-type tyrosine-protein phosphatase delta
Authors:Yamagata, A, Fukai, S.
Deposit date:2015-02-25
Release date:2015-05-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.253 Å)
Cite:Mechanisms of splicing-dependent trans-synaptic adhesion by PTP delta-IL1RAPL1/IL-1RAcP for synaptic differentiation.
Nat Commun, 6, 2015
4YLS
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BU of 4yls by Molmil
Tubulin Glutamylase
Descriptor: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Tubulin polyglutamylase TTLL7
Authors:Garnham, C.P, Vemu, A, Wilson-Kubalek, E.M, Yu, I, Szyk, A, Lander, G.C, Milligan, R.A, Roll-Mecak, A.
Deposit date:2015-03-05
Release date:2015-06-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Multivalent Microtubule Recognition by Tubulin Tyrosine Ligase-like Family Glutamylases.
Cell, 161, 2015
4YM6
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BU of 4ym6 by Molmil
Crystal structure of the human nucleosome containing 6-4PP (outside)
Descriptor: 145-MER DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Osakabe, A, Tachiwana, H, Kagawa, W, Horikoshi, N, Matsumoto, S, Hasegawa, M, Matsumoto, N, Toga, T, Yamamoto, J, Hanaoka, F, Thoma, N.H, Sugasawa, K, Iwai, S, Kurumizaka, H.
Deposit date:2015-03-06
Release date:2015-12-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.514 Å)
Cite:Structural basis of pyrimidine-pyrimidone (6-4) photoproduct recognition by UV-DDB in the nucleosome
Sci Rep, 5, 2015
4YP1
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BU of 4yp1 by Molmil
Misting with CDA
Descriptor: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, Stimulator of interferon genes protein
Authors:Chin, K.H, Chen, C.K, Tu, Z.I, Chou, S.H.
Deposit date:2015-03-12
Release date:2015-10-07
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural Insights into the Distinct Binding Mode of Cyclic Di-AMP with SaCpaA_RCK.
Biochemistry, 54, 2015
4YM5
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BU of 4ym5 by Molmil
Crystal structure of the human nucleosome containing 6-4PP (inside)
Descriptor: 144 mer-DNA, 144-mer DNA, Histone H2A type 1-B/E, ...
Authors:Osakabe, A, Tachiwana, H, Kagawa, W, Horikoshi, N, Matsumoto, S, Hasegawa, M, Matsumoto, N, Toga, T, Yamamoto, J, Hanaoka, F, Thoma, N.H, Sugasawa, K, Iwai, S, Kurumizaka, H.
Deposit date:2015-03-06
Release date:2015-12-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (4.005 Å)
Cite:Structural basis of pyrimidine-pyrimidone (6-4) photoproduct recognition by UV-DDB in the nucleosome
Sci Rep, 5, 2015
3G5P
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BU of 3g5p by Molmil
Structure and activity of human mitochondrial peptide deformylase, a novel cancer target
Descriptor: COBALT (II) ION, PHOSPHATE ION, Peptide deformylase, ...
Authors:Escobar-Alvarez, S, Goldgur, Y, Yang, G, Ouerfelli, O, Li, Y, Scheinberg, D.A.
Deposit date:2009-02-05
Release date:2009-04-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure and activity of human mitochondrial peptide deformylase, a novel cancer target
J.Mol.Biol., 387, 2009
4YBH
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BU of 4ybh by Molmil
Crystal structure of the human RAGE ectodomain (VC1C2 fragment) in complex with human S100A6
Descriptor: ACETATE ION, Advanced glycosylation end product-specific receptor, CALCIUM ION, ...
Authors:Yatime, L, Andersen, G.R.
Deposit date:2015-02-18
Release date:2016-03-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Structure of the RAGE:S100A6 Complex Reveals a Unique Mode of Homodimerization for S100 Proteins.
Structure, 24, 2016
4YLR
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BU of 4ylr by Molmil
Tubulin Glutamylase
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Tubulin polyglutamylase TTLL7
Authors:Garnham, C.P, Vemu, A, Wilson-Kubalek, E.M, Yu, I, Szyk, A, Lander, G.C, Milligan, R.A, Roll-Mecak, A.
Deposit date:2015-03-05
Release date:2015-06-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Multivalent Microtubule Recognition by Tubulin Tyrosine Ligase-like Family Glutamylases.
Cell, 161, 2015
4YZK
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BU of 4yzk by Molmil
Crystal structure of the indole prenyltransferase TleC apo structure
Descriptor: Tryptophan dimethylallyltransferase
Authors:Mori, T, Morita, H, Abe, I.
Deposit date:2015-03-25
Release date:2016-03-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Manipulation of prenylation reactions by structure-based engineering of bacterial indolactam prenyltransferases.
Nat Commun, 7, 2016
7EQ7
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BU of 7eq7 by Molmil
Co-Crystal Structure Analysis of Annexin A2 and 5alpha-EAL
Descriptor: Annexin A2, CALCIUM ION
Authors:Liu, X, Yang, G.
Deposit date:2021-04-30
Release date:2022-05-11
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.111 Å)
Cite:Co-Crystal Structure Analysis of Annexin A2 and 5alpha-EAL
To be published
3GYR
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BU of 3gyr by Molmil
Structure of Phenoxazinone synthase from Streptomyces antibioticus reveals a new type 2 copper center.
Descriptor: COPPER (II) ION, CU-O-CU LINKAGE, GLYCEROL, ...
Authors:Smith, A.W, Camara-Artigas, A, Wang, M, Francisco, W.A, Allen, J.P.
Deposit date:2009-04-05
Release date:2009-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of Phenoxazinone Synthase from Streptomyces Antibioticus Reveals a New Type 2 Copper Center.
Biochemistry, 45, 2006
6DWN
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BU of 6dwn by Molmil
Structure of Human Cytochrome P450 1A1 with Erlotinib
Descriptor: 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Cytochrome P450 1A1, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Bart, A.G, Scott, E.E.
Deposit date:2018-06-26
Release date:2018-10-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structures of human cytochrome P450 1A1 with bergamottin and erlotinib reveal active-site modifications for binding of diverse ligands.
J. Biol. Chem., 293, 2018
4G45
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BU of 4g45 by Molmil
Structure of cytochrome CYP121 in complex with 2-methylquinolin-6-amine
Descriptor: 2-methylquinolin-6-amine, Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Hudson, S.A, McLean, K.J, Surade, S, Yang, Y.-Q, Leys, D, Ciulli, A, Munro, A.W, Abell, C.
Deposit date:2012-07-16
Release date:2012-09-05
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Application of Fragment Screening and Merging to the Discovery of Inhibitors of the Mycobacterium tuberculosis Cytochrome P450 CYP121
Angew.Chem.Int.Ed.Engl., 51, 2012
4G46
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BU of 4g46 by Molmil
Structure of cytochrome P450 CYP121 in complex with 4-oxo-4,5,6,7-tetrahydrobenzofuran-3-carboxylate
Descriptor: 4-oxo-4,5,6,7-tetrahydro-1-benzofuran-3-carboxylic acid, Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Hudson, S.A, McLean, K.J, Surade, S, Yang, Y.-Q, Leys, D, Ciulli, A, Munro, A.W, Abell, C.
Deposit date:2012-07-16
Release date:2012-09-05
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Application of Fragment Screening and Merging to the Discovery of Inhibitors of the Mycobacterium tuberculosis Cytochrome P450 CYP121
Angew.Chem.Int.Ed.Engl., 51, 2012
4FYZ
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BU of 4fyz by Molmil
Crystal Structure of Nitrosyl Cytochrome P450cin
Descriptor: 1,3,3-TRIMETHYL-2-OXABICYCLO[2.2.2]OCTANE, DI(HYDROXYETHYL)ETHER, NITRIC OXIDE, ...
Authors:Madrona, Y, Tripathi, S.M, Li, H, Poulos, T.L.
Deposit date:2012-07-05
Release date:2012-07-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Crystal structures of substrate-free and nitrosyl cytochrome p450cin: implications for o(2) activation.
Biochemistry, 51, 2012
1T5B
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BU of 1t5b by Molmil
Structural genomics, A protein from Salmonella typhimurium similar to E. coli acyl carrier protein phosphodiesterase
Descriptor: Acyl carrier protein phosphodiesterase, FLAVIN MONONUCLEOTIDE
Authors:Zhang, R, Wu, R, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2004-05-03
Release date:2004-08-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:1.4 A crystal structure of a protein from Salmonella typhimurium similar to E. coli acyl carrier protein phosphodiesterase
To be Published

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