PDB: 72960 resultsInfo pagesStatus searchChemie searchBIRD

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5TCU	Methicillin sensitive Staphylococcus aureus 70S ribosome Descriptor: 16S RRNA, 23S RRNA, 30S ribosomal protein S10, ... Authors: Eyal, Z, Ahmed, T, Belousoff, N, Mishra, S, Matzov, D, Bashan, A, Zimmerman, E, Lithgow, T, Bhushan, S, Yonath, A. Deposit date: 2016-09-15 Release date: 2017-05-24 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structural Basis for Linezolid Binding Site Rearrangement in the Staphylococcus aureus Ribosome. MBio, 8, 2017
6WC1	Peptide-bound SARS-CoV-2 Nsp9 RNA-replicase Descriptor: SARS-coV-2 Non-structural protein 9, SULFATE ION Authors: Littler, D.R, Gully, B.S, Rossjohn, J. Deposit date: 2020-03-28 Release date: 2020-08-05 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Identification of a putative peptide-binding site at the dimer interface of the SARS-CoV-2 Nsp9 RNA-replicase. To Be Published
2ETJ	Crystal structure of Ribonuclease HII (EC 3.1.26.4) (RNase HII) (tm0915) from THERMOTOGA MARITIMA at 1.74 A resolution Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ... Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2005-10-27 Release date: 2005-11-08 Last modified: 2023-01-25 Method: X-RAY DIFFRACTION (1.74 Å) Cite: Crystal structure of Ribonuclease HII (EC 3.1.26.4) (RNase HII) (tm0915) from THERMOTOGA MARITIMA at 1.74 A resolution To be published
3TM5	Crystal structure of Trm14 from Pyrococcus furiosus in complex with sinefungin Descriptor: Crystal structure of Trm14, SINEFUNGIN Authors: Fislage, M, Roovers, M, Tuszynska, I, Bujnicki, J.M, Droogmans, L, Versees, W. Deposit date: 2011-08-31 Release date: 2012-03-14 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.27 Å) Cite: Crystal structures of the tRNA:m2G6 methyltransferase Trm14/TrmN from two domains of life. Nucleic Acids Res., 40, 2012
2CJR	Crystal structure of oligomerization domain of SARS coronavirus nucleocapsid protein. Descriptor: NUCLEOCAPSID PROTEIN Authors: Chen, C.-Y, Hsiao, C.-D. Deposit date: 2006-04-06 Release date: 2007-04-10 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure of the Sars Coronavirus Nucleocapsid Protein RNA-Binding Dimerization Domain Suggests a Mechanism for Helical Packaging of Viral RNA. J.Mol.Biol., 368, 2007
2HWX	Structure of human SMG6 E1282C PIN domain mutant. Descriptor: Telomerase-binding protein EST1A Authors: Glavan, F, Behm-Ansmant, I, Izaurralde, E, Conti, E. Deposit date: 2006-08-02 Release date: 2006-11-14 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex. Embo J., 25, 2006
2HWY	Structure of PIN domain of human SMG5. Descriptor: Protein SMG5 Authors: Glavan, F, Behm-Ansmant, I, Izaurralde, E, Conti, E. Deposit date: 2006-08-02 Release date: 2006-11-14 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex. Embo J., 25, 2006
1QZW	Crystal structure of the complete core of archaeal SRP and implications for inter-domain communication Descriptor: 7S RNA, Signal recognition 54 kDa protein Authors: Rosendal, K.R, Wild, K, Montoya, G, Sinning, I. Deposit date: 2003-09-18 Release date: 2003-11-18 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (4.1 Å) Cite: Crystal structure of the complete core of archaeal signal recognition particle and implications for interdomain communication Proc.Natl.Acad.Sci.USA, 100, 2003
4OGC	Crystal structure of the Type II-C Cas9 enzyme from Actinomyces naeslundii Descriptor: ACETATE ION, HNH endonuclease domain protein, MAGNESIUM ION, ... Authors: Jiang, F, Ma, E, Lin, S, Doudna, J.A. Deposit date: 2014-01-15 Release date: 2014-02-12 Last modified: 2014-03-26 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structures of Cas9 endonucleases reveal RNA-mediated conformational activation. Science, 343, 2014
2AHV	Crystal Structure of Acyl-CoA transferase from E. coli O157:H7 (YdiF)-thioester complex with CoA- 1 Descriptor: COENZYME A, putative enzyme YdiF Authors: Rangarajan, E.S, Li, Y, Ajamian, E, Iannuzzi, P, Kernaghan, S.D, Fraser, M.E, Cygler, M, Matte, A, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) Deposit date: 2005-07-28 Release date: 2005-11-01 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystallographic trapping of the glutamyl-CoA thioester intermediate of family I CoA transferases. J.Biol.Chem., 280, 2005
4OGE	Crystal structure of the Type II-C Cas9 enzyme from Actinomyces naeslundii Descriptor: HNH endonuclease domain protein, MAGNESIUM ION, SPERMIDINE, ... Authors: Jiang, F, Ma, E, Lin, S, Doudna, J.A. Deposit date: 2014-01-15 Release date: 2014-02-12 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.201 Å) Cite: Structures of Cas9 endonucleases reveal RNA-mediated conformational activation. Science, 343, 2014
2AWV	NMR Structural Analysis of the dimer of 5MCCTCATCC Descriptor: 5'-D(*(MCY)P*CP*TP*CP*AP*CP*TP*CP*C)-3' Authors: Canalia, M, Leroy, J.-L. Deposit date: 2005-09-02 Release date: 2005-09-20 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Structure, internal motions and association-dissociation kinetics of the i-motif dimer of d(5mCCTCACTCC). Nucleic Acids Res., 33, 2005
7Z4E	SpCas9 bound to 8-nucleotide complementary DNA substrate Descriptor: CRISPR-associated endonuclease Cas9/Csn1, Non-target strand of 8 nucleotide complementary DNA substrate, Target strand of 8 nucleotide complementary DNA substrate, ... Authors: Pacesa, M, Jinek, M. Deposit date: 2022-03-03 Release date: 2022-08-31 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (4.14 Å) Cite: R-loop formation and conformational activation mechanisms of Cas9. Nature, 609, 2022
7Z4I	SpCas9 bound to 16-nucleotide complementary DNA substrate Descriptor: CRISPR-associated endonuclease Cas9/Csn1, Non-target strand of 16-nucleotide complementary DNA substrate, POTASSIUM ION, ... Authors: Pacesa, M, Jinek, M. Deposit date: 2022-03-03 Release date: 2022-08-31 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (3.12 Å) Cite: R-loop formation and conformational activation mechanisms of Cas9. Nature, 609, 2022
7Z4C	SpCas9 bound to 6 nucleotide complementary DNA substrate Descriptor: CRISPR-associated endonuclease Cas9/Csn1, Non-target strand of 6 nucleotide complementary DNA substrate, Target strand of 6 nucleotide complementary DNA substrate, ... Authors: Pacesa, M, Jinek, M. Deposit date: 2022-03-03 Release date: 2022-08-31 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (3.87 Å) Cite: R-loop formation and conformational activation mechanisms of Cas9. Nature, 609, 2022
7Z4G	SpCas9 bound to 12-nucleotide complementary DNA substrate Descriptor: CRISPR-associated endonuclease Cas9/Csn1, Non-target strand of 12-nucleotide complementary DNA substrate, Target strand of 12-nucleotide complementary DNA substrate, ... Authors: Pacesa, M, Jinek, M. Deposit date: 2022-03-03 Release date: 2022-08-31 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (3.64 Å) Cite: R-loop formation and conformational activation mechanisms of Cas9. Nature, 609, 2022
7Z4H	SpCas9 bound to 14-nucleotide complementary DNA substrate Descriptor: CRISPR-associated endonuclease Cas9/Csn1, Non-target strand of 14-nucleotide complementary DNA substrate, Target strand of 14-nucleotide complementary DNA substrate, ... Authors: Pacesa, M, Jinek, M. Deposit date: 2022-03-03 Release date: 2022-08-31 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (3.49 Å) Cite: R-loop formation and conformational activation mechanisms of Cas9. Nature, 609, 2022
7Z4K	SpCas9 bound to 10-nucleotide complementary DNA substrate Descriptor: CRISPR-associated endonuclease Cas9/Csn1, Non-target strand of 10-nucleotide complementary DNA substrate, Target strand of 10-nucleotide complementary DNA substrate, ... Authors: Pacesa, M, Jinek, M. Deposit date: 2022-03-04 Release date: 2022-08-31 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (3.81 Å) Cite: R-loop formation and conformational activation mechanisms of Cas9. Nature, 609, 2022
7Z4J	SpCas9 bound to 18-nucleotide complementary DNA substrate in the catalytic state Descriptor: CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, Non-target strand of 18-nucleotide complementary DNA substrate, ... Authors: Pacesa, M, Jinek, M. Deposit date: 2022-03-03 Release date: 2022-08-31 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (2.99 Å) Cite: R-loop formation and conformational activation mechanisms of Cas9. Nature, 609, 2022
7Z4L	SpCas9 bound to 18-nucleotide complementary DNA substrate in the checkpoint state Descriptor: CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, Non-target strand of 18-nucleotide complementary DNA substrate, ... Authors: Pacesa, M, Jinek, M. Deposit date: 2022-03-04 Release date: 2022-08-31 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (2.54 Å) Cite: R-loop formation and conformational activation mechanisms of Cas9. Nature, 609, 2022
7SBE	Structure of the K. lactis telomerase RNA binding domain Descriptor: Telomerase reverse transcriptase Authors: Skordalakes, E, Tzfati, Y. Deposit date: 2021-09-24 Release date: 2022-09-21 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Structure of the K. lactis telomerase RNA binding domain Int J Mol Sci, 2022
2AHU	Crystal structure of Acyl-CoA transferase (YdiF) apoenzyme from Escherichia coli O157:H7. Descriptor: putative enzyme ydiF Authors: Rangarajan, E.S, Li, Y, Ajamian, E, Iannuzzi, P, Kernaghan, S.D, Fraser, M.E, Cygler, M, Matte, A, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) Deposit date: 2005-07-28 Release date: 2005-11-01 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystallographic trapping of the glutamyl-CoA thioester intermediate of family I CoA transferases. J.Biol.Chem., 280, 2005
7K87	The crystal structure of the 2009 H1N1 PA endonuclease in complex with SJ000986436 Descriptor: 2-(2,6-difluorophenyl)-5-hydroxy-N-[2-(2-methoxypyridin-4-yl)ethyl]-6-oxo-3,6-dihydropyrimidine-4-carboxamide, Hexa Vinylpyrrolidone K15, MANGANESE (II) ION, ... Authors: Cuypers, M.G, Slavish, P.J, Jayaraman, S, Rankovic, Z, White, S.W. Deposit date: 2020-09-25 Release date: 2021-09-29 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential. Eur.J.Med.Chem., 247, 2023
2B4G	dihydroorotate dehydrogenase Descriptor: BROMIDE ION, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... Authors: Arakaki, T.L, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) Deposit date: 2005-09-23 Release date: 2005-10-11 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Characterization of Trypanosoma brucei dihydroorotate dehydrogenase as a possible drug target; structural, kinetic and RNAi studies Mol.Microbiol., 68, 2008
7CUX	Crystal structure of human Schlafen 5 N'-terminal domain (SLFN5-N) involved in ssRNA cleaving and DNA binding Descriptor: Schlafen family member 5, ZINC ION Authors: Yang, J.Y, Luo, M, Ou, J.Y, Wang, Z.W, Gao, S. Deposit date: 2020-08-25 Release date: 2021-08-25 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (3.29477072 Å) Cite: Crystal structure of human Schlafen 5 N'-terminal domain (SLFN5-N) involved in ssRNA cleaving and DNA binding To Be Published

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