2B4G

dihydroorotate dehydrogenase

Summary for 2B4G

Entry DOI	10.2210/pdb2b4g/pdb
Descriptor	dihydroorotate dehydrogenase, BROMIDE ION, FLAVIN MONONUCLEOTIDE, ... (6 entities in total)
Functional Keywords	structural genomics, psi, protein structure initiative, structural genomics of pathogenic protozoa consortium, sgpp, oxidoreductase
Biological source	Trypanosoma brucei
Cellular location	Cytoplasm : Q57U83
Total number of polymer chains	4
Total formula weight	141591.70
Authors	Arakaki, T.L.,Merritt, E.A.,Structural Genomics of Pathogenic Protozoa Consortium (SGPP) (deposition date: 2005-09-23, release date: 2005-10-11, Last modification date: 2023-09-20)
Primary citation	Arakaki, T.L.,Buckner, F.S.,Gillespie, J.R.,Malmquist, N.A.,Phillips, M.A.,Kalyuzhniy, O.,Luft, J.R.,Detitta, G.T.,Verlinde, C.L.,Van Voorhis, W.C.,Hol, W.G.,Merritt, E.A. Characterization of Trypanosoma brucei dihydroorotate dehydrogenase as a possible drug target; structural, kinetic and RNAi studies Mol.Microbiol., 68:37-50, 2008 Cited by PubMed: 18312275 DOI: 10.1111/j.1365-2958.2008.06131.x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation