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1XDX
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BU of 1xdx by Molmil
Solution Structure of the Tctex1 Light Chain From Chlamydomonas Inner Dynein Arm I1
Descriptor: Tctex1 Light Chain protein
Authors:Wu, H, Maciejewski, M.W, Takebe, S, King, S.M.
Deposit date:2004-09-08
Release date:2005-03-01
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution Structure of the Tctex1 Dimer Reveals a Mechanism for Dynein-Cargo Interactions
Structure, 13, 2005
1I5E
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BU of 1i5e by Molmil
CRYSTAL STRUCTURE OF BACILLUS CALDOLYTICUS URACIL PHOSPHORIBOSYLTRANSFERASE WITH BOUND UMP
Descriptor: URACIL PHOSPHORIBOSYLTRANSFERASE, URIDINE-5'-MONOPHOSPHATE
Authors:Kadziola, A, Neuhard, J, Larsen, S.
Deposit date:2001-02-27
Release date:2002-06-05
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of product-bound Bacillus caldolyticus uracil phosphoribosyltransferase confirms ordered sequential substrate binding.
Acta Crystallogr.,Sect.D, 58, 2002
1XNL
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BU of 1xnl by Molmil
ASLV fusion peptide
Descriptor: membrane protein gp37
Authors:Cheng, S.F, Wu, C.W, Kantchev, E.A, Chang, D.K.
Deposit date:2004-10-05
Release date:2005-01-11
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Structure and membrane interaction of the internal fusion peptide of avian sarcoma leukosis virus
Eur.J.Biochem., 271, 2004
1MW5
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BU of 1mw5 by Molmil
Structure of HI1480 from Haemophilus influenzae
Descriptor: HYPOTHETICAL PROTEIN HI1480
Authors:Lim, K, Sarikaya, E, Howard, A, Galkin, A, Herzberg, O, Structure 2 Function Project (S2F)
Deposit date:2002-09-27
Release date:2003-11-18
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Novel structure and nucleotide binding properties of HI1480 from Haemophilus influenzae: a protein with no known sequence homologues
PROTEINS: STRUCT.,FUNCT.,GENET., 56, 2004
1XYD
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BU of 1xyd by Molmil
NMR Solution Structure of Rat Zinc-Calcium-S100B, 20 Structures
Descriptor: CALCIUM ION, S-100 protein, beta chain, ...
Authors:Wilder, P.T, Varney, K.M, Weber, D.J.
Deposit date:2004-11-09
Release date:2005-06-07
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution Structure of Zinc- and Calcium-Bound Rat S100B as Determined by Nuclear Magnetic Resonance Spectroscopy
Biochemistry, 44, 2005
6OF2
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BU of 6of2 by Molmil
Precursor ribosomal RNA processing complex, State 2.
Descriptor: CLP1_P domain-containing protein, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Pillon, M.C, Hsu, A.L, Krahn, J.M, Williams, J.G, Goslen, K.H, Sobhany, M, Borgnia, M.J, Stanley, R.E.
Deposit date:2019-03-28
Release date:2019-09-11
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Cryo-EM reveals active site coordination within a multienzyme pre-rRNA processing complex.
Nat.Struct.Mol.Biol., 26, 2019
1N28
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BU of 1n28 by Molmil
Crystal structure of the H48Q mutant of human group IIA phospholipase A2
Descriptor: CALCIUM ION, Phospholipase A2, membrane associated
Authors:Edwards, S.H, Thompson, D, Baker, S.F, Wood, S.P, Wilton, D.C.
Deposit date:2002-10-22
Release date:2003-10-28
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The crystal structure of the H48Q active site mutant of human group IIA secreted phospholipase A2 at 1.5 A resolution provides an insight into the catalytic mechanism
Biochemistry, 41, 2002
1KO7
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BU of 1ko7 by Molmil
X-ray structure of the HPr kinase/phosphatase from Staphylococcus xylosus at 1.95 A resolution
Descriptor: Hpr kinase/phosphatase, PHOSPHATE ION
Authors:Marquez, J.A, Hasenbein, S, Koch, B, Fieulaine, S, Nessler, S, Hengstenberg, W, Scheffzek, K.
Deposit date:2001-12-20
Release date:2002-04-03
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of the full-length HPr kinase/phosphatase from Staphylococcus xylosus at 1.95 A resolution: Mimicking the product/substrate of the phospho transfer reactions.
Proc.Natl.Acad.Sci.USA, 99, 2002
1X9K
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An all-RNA Hairpin Ribozyme with mutation U39C
Descriptor: 5'-R(*AP*AP*UP*AP*GP*AP*GP*AP*AP*GP*CP*GP*A)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*GP*CP*AP*GP*UP*CP*CP*UP*AP*UP*U)-3', ...
Authors:Alam, S, Grum-Tokars, V, Krucinska, J, Kundracik, M.L, Wedekind, J.E.
Deposit date:2004-08-21
Release date:2005-11-22
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:Conformational Heterogeneity at Position U37 of an All-RNA Hairpin Ribozyme with Implications for Metal Binding and the Catalytic Structure of the S-Turn.
Biochemistry, 44, 2005
8WWO
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BU of 8wwo by Molmil
Crystal structure of the AFSV topoisomerase ATPase domain in complex with AMPPNP
Descriptor: DNA topoisomerase 2, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Kuang, W, Deng, Z.
Deposit date:2023-10-26
Release date:2024-02-21
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure-function analysis of the ATPase domain of African swine fever virus topoisomerase.
Mbio, 15, 2024
8G9B
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BU of 8g9b by Molmil
Human IMPDH2 mutant - L245P, treated with GTP, ATP, IMP, and NAD+; compressed filament segment reconstruction
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ...
Authors:O'Neill, A.G, Kollman, J.M.
Deposit date:2023-02-21
Release date:2023-04-19
Last modified:2023-08-09
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Neurodevelopmental disorder mutations in the purine biosynthetic enzyme IMPDH2 disrupt its allosteric regulation.
J.Biol.Chem., 299, 2023
5MDM
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BU of 5mdm by Molmil
Structural intermediates in the fusion associated transition of vesiculovirus glycoprotein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Baquero, E, Albertini, A.A, Gaudin, Y, Bressanelli, S.
Deposit date:2016-11-11
Release date:2016-12-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.998 Å)
Cite:Structural intermediates in the fusion-associated transition of vesiculovirus glycoprotein.
EMBO J., 36, 2017
6O98
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BU of 6o98 by Molmil
Crystal structure of RAR-related orphan receptor C in complex with a phenyl (3-phenylpyrrolidin-3-yl)sulfone inhibitor
Descriptor: 1-(4-{(3R)-3-[(4-fluorophenyl)sulfonyl]-3-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]pyrrolidine-1-carbonyl}piperazin-1-yl)ethan-1-one, Nuclear receptor ROR-gamma
Authors:Sack, J.S.
Deposit date:2019-03-13
Release date:2019-03-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Structure-based Discovery of Phenyl (3-Phenylpyrrolidin-3-yl)sulfones as Selective, Orally Active ROR gamma t Inverse Agonists.
ACS Med Chem Lett, 10, 2019
4GUA
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BU of 4gua by Molmil
Alphavirus P23pro-zbd
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Non-structural polyprotein, SULFATE ION, ...
Authors:Shin, G, Yost, S, Miller, M, Marcotrigiano, J.
Deposit date:2012-08-29
Release date:2012-10-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.854 Å)
Cite:Structural and functional insights into alphavirus polyprotein processing and pathogenesis.
Proc.Natl.Acad.Sci.USA, 109, 2012
8FCB
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BU of 8fcb by Molmil
Cryo-EM structure of the human TRPV4 - RhoA in complex with GSK1016790A
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, CHOLESTEROL HEMISUCCINATE, N-[(2S)-1-{4-[N-(2,4-dichlorobenzene-1-sulfonyl)-L-seryl]piperazin-1-yl}-4-methyl-1-oxopentan-2-yl]-1-benzothiophene-2-carboxamide, ...
Authors:Kwon, D.H, Lee, S.-Y, Zhang, F.
Deposit date:2022-12-01
Release date:2023-07-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.52 Å)
Cite:TRPV4-Rho GTPase complex structures reveal mechanisms of gating and disease.
Nat Commun, 14, 2023
1YPR
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BU of 1ypr by Molmil
SACCHAROMYCES CEREVISIAE (YEAST) PROFILIN
Descriptor: PROFILIN
Authors:Eads, J.C, Mahoney, N.M, Almo, S.C.
Deposit date:1997-06-26
Release date:1997-12-31
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure determination and characterization of Saccharomyces cerevisiae profilin
Biochemistry, 37, 1998
8CWW
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BU of 8cww by Molmil
Structure of S. cerevisiae Hop1 CBR bound to a nucleosome
Descriptor: Histone H2A, Histone H2B, Histone H3, ...
Authors:Gu, Y, Ur, S.N, Milano, C.R, Tromer, E.C, Vale-Silva, L.A, Hochwagen, A, Corbett, K.D.
Deposit date:2022-05-19
Release date:2023-06-07
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (2.74 Å)
Cite:Chromatin binding by HORMAD proteins regulates meiotic recombination initiation.
Embo J., 43, 2024
1KA8
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BU of 1ka8 by Molmil
Crystal Structure of the Phage P4 Origin-Binding Domain
Descriptor: putative P4-specific DNA primase
Authors:Yeo, H.J, Ziegelin, G, Korolev, S, Calendar, R, Lanka, E, Waksman, G.
Deposit date:2001-10-31
Release date:2002-04-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Phage P4 origin-binding domain structure reveals a mechanism for regulation of DNA-binding activity by homo- and heterodimerization of winged helix proteins.
Mol.Microbiol., 43, 2002
1YI5
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BU of 1yi5 by Molmil
Crystal structure of the a-cobratoxin-AChBP complex
Descriptor: Acetylcholine-binding protein, Long neurotoxin 1
Authors:Bourne, Y, Talley, T.T, Hansen, S.B, Taylor, P, Marchot, P.
Deposit date:2005-01-11
Release date:2005-05-17
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Crystal structure of a Cbtx-AChBP complex reveals essential interactions between snake alpha-neurotoxins and nicotinic receptors
Embo J., 24, 2005
8CZE
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BU of 8cze by Molmil
Structure of a Xenopus Nucleosome with Widom 601 DNA
Descriptor: Histone H2A, Histone H2B, Histone H3, ...
Authors:Gu, Y, Ur, S.N, Milano, C.R, Tromer, E.C, Vale-Silva, L.A, Hochwagen, A, Corbett, K.D.
Deposit date:2022-05-24
Release date:2023-06-07
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (2.58 Å)
Cite:Chromatin binding by HORMAD proteins regulates meiotic recombination initiation.
Embo J., 43, 2024
1K8X
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BU of 1k8x by Molmil
Crystal Structure Of AlphaT183V Mutant Of Tryptophan Synthase From Salmonella Typhimurium
Descriptor: PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, TRYPTOPHAN SYNTHASE, ...
Authors:Kulik, V, Weyand, M, Siedel, R, Niks, D, Arac, D, Dunn, M.F, Schlichting, I.
Deposit date:2001-10-26
Release date:2002-12-18
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:On the Role of AlphaThr183 in the Allosteric Regulation and Catalytic Mechanism of Tryptophan Synthase
J.Mol.Biol., 324, 2002
1O72
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BU of 1o72 by Molmil
Crystal structure of the water-soluble state of the pore-forming cytolysin Sticholysin II complexed with phosphorylcholine
Descriptor: PHOSPHOCHOLINE, STICHOLYSIN II
Authors:Mancheno, J.M, Martinez-Ripoll, M, Gavilanes, J.G, Hermoso, J.A.
Deposit date:2002-10-23
Release date:2003-11-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Crystal and Electron Microscopy Structures of Sticholysin II Actinoporin Reveal Insights Into the Mechanism of Membrane Pore Formation
Structure, 11, 2003
8FZZ
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BU of 8fzz by Molmil
Phocaeicola vulgatus type VI secretion system Ntox15 effector and immunity Tde2/Tdi2
Descriptor: DUF1851 domain-containing protein, Ntox15 domain-containing protein
Authors:Bosch, D.E, Mougous, J.D.
Deposit date:2023-01-30
Release date:2023-07-05
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Structural disruption of Ntox15 nuclease effector domains by immunity proteins protects against type VI secretion system intoxication in Bacteroidales.
Mbio, 14, 2023
8FC7
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Cryo-EM structure of the human TRPV4 - RhoA in complex with GSK2798745
Descriptor: 1-({(5S,7S)-3-[5-(2-hydroxypropan-2-yl)pyrazin-2-yl]-7-methyl-2-oxo-1-oxa-3-azaspiro[4.5]decan-7-yl}methyl)-1H-benzimidazole-6-carbonitrile, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kwon, D.H, Lee, S.-Y, Zhang, F.
Deposit date:2022-12-01
Release date:2023-07-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:TRPV4-Rho GTPase complex structures reveal mechanisms of gating and disease.
Nat Commun, 14, 2023
8FC9
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Cryo-EM structure of the human TRPV4 - RhoA, apo condition
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Transforming protein RhoA, ...
Authors:Kwon, D.H, Lee, S.-Y, Zhang, F.
Deposit date:2022-12-01
Release date:2023-07-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:TRPV4-Rho GTPase complex structures reveal mechanisms of gating and disease.
Nat Commun, 14, 2023

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