PDB: 30805 resultsInfo pagesStatus searchChemie searchBIRD

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6UY4	Crystal structure of dihydroorotate dehydrogenase from Schistosoma mansoni Descriptor: 2-[(4-fluorophenyl)amino]-3-hydroxynaphthalene-1,4-dione, Dihydroorotate dehydrogenase, FLAVIN MONONUCLEOTIDE, ... Authors: Mori, R.M, Zapata, L.C.C, Nonato, M.C. Deposit date: 2019-11-11 Release date: 2020-05-27 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.796 Å) Cite: Structural basis for the function and inhibition of dihydroorotate dehydrogenase from Schistosoma mansoni. Febs J., 288, 2021
5C8N	EGFR kinase domain mutant "TMLR" with compound 23 Descriptor: Epidermal growth factor receptor, N-{2-[4-(2-aminoethyl)-4-methoxypiperidin-1-yl]pyrimidin-4-yl}-2-methyl-1-(propan-2-yl)-1H-imidazo[4,5-c]pyridin-6-amine, SULFATE ION Authors: Eigenbrot, C, Yu, C. Deposit date: 2015-06-25 Release date: 2015-10-28 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.401 Å) Cite: Noncovalent Mutant Selective Epidermal Growth Factor Receptor Inhibitors: A Lead Optimization Case Study. J.Med.Chem., 58, 2015
7SZD	Crystal Structure Analysis of human PRPK complex with a compound Descriptor: 2-[(3R)-3-methyl-2,6-dioxopiperidin-3-yl]-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylic acid, EKC/KEOPS complex subunit TP53RK, EKC/KEOPS complex subunit TPRKB Authors: Seo, H.-S, Dhe-Paganon, S. Deposit date: 2021-11-27 Release date: 2022-12-14 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Development of PRPK Directed Phthalimides Biorxiv, 2021
6VET	Human insulin analog: [GluB10,HisA8,ArgA9,TyrB20]-DOI Descriptor: Insulin A chain, Insulin B chain Authors: Menting, J.G, Chou, D.H.-C, Lawrence, M.C, Xiong, X. Deposit date: 2020-01-02 Release date: 2020-06-03 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.46 Å) Cite: A structurally minimized yet fully active insulin based on cone-snail venom insulin principles. Nat.Struct.Mol.Biol., 27, 2020
7OBY	Crystal structure of 14-3-3 sigma in complex with SSBP4 phosphopeptide and stabilizer Fusicoccin-A Descriptor: 14-3-3 protein sigma, CHLORIDE ION, FUSICOCCIN, ... Authors: Centorrino, F, Andlovic, B, Ottmann, C. Deposit date: 2021-04-24 Release date: 2022-05-04 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.1 Å) Cite: IFN alpha primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization. Cell Chem Biol, 2023
8DHE	Tannerella forsythia beta-glucuronidase (mL1) Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... Authors: Lietzan, A.D, Redinbo, M.R. Deposit date: 2022-06-27 Release date: 2023-05-17 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Microbial beta-glucuronidases drive human periodontal disease etiology. Sci Adv, 9, 2023
8CRY	Crystal structure of alien DNA CTSZZPBSBSZPPBAG in an orthorhombic lattice Descriptor: DNA (5'-D(*CP*TP*(JSP)P*(1W5)P*(1W5)P*(1WA)P*(IGU)P*(JSP)P*(IGU)P*(JSP)P*(1W5)P*(1WA)P*(1WA)P*(IGU)P*AP*G)-3'), MAGNESIUM ION Authors: Georgiadis, M.M. Deposit date: 2022-05-12 Release date: 2023-05-17 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.2 Å) Cite: Alien DNA visualized at high resolution in A- and B-forms To Be Published
7T5M	Structure of HLA-A*02:01-FLPTPEELGLLGPPRPQVLA complex Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-2-microglobulin, Interleukin-27 receptor subunit alpha, ... Authors: Gras, S. Deposit date: 2021-12-12 Release date: 2022-12-14 Last modified: 2024-01-03 Method: X-RAY DIFFRACTION (1.67 Å) Cite: Cutting Edge: Unconventional CD8 + T Cell Recognition of a Naturally Occurring HLA-A*02:01-Restricted 20mer Epitope. J Immunol., 208, 2022
6M2R	X-ray structure of a functional Drosophila dopamine transporter in L-norepinephrine bound form Descriptor: Antibody fragment 9D5 Light chain, Antibody fragment 9D5 heavy chain, CHLORIDE ION, ... Authors: Shabareesh, P, Mallela, A.K, Joseph, D, Penmatsa, A. Deposit date: 2020-02-28 Release date: 2021-02-17 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.802 Å) Cite: Structural basis of norepinephrine recognition and transport inhibition in neurotransmitter transporters. Nat Commun, 12, 2021
6M30	Crystal structure of a mutant Staphylococcus equorum manganese superoxide dismutase N73F Descriptor: MANGANESE (II) ION, Superoxide dismutase Authors: Retnoningrum, D.S, Yoshida, H, Razani, M.D, Meidianto, V.F, Hartanto, A, Artarini, A, Ismaya, W.T. Deposit date: 2020-03-02 Release date: 2021-02-10 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.74 Å) Cite: Unprecedented Role of The N73-F124 Pair in The Staphylococcus equorum MnSOD Activity. Curr Enzym Inhib, 2021
8CS0	Crystal structure of alien DNA CTSZZPBSBSZPPBAG in a host-guest complex with the N-terminal fragment of Moloney murine leukemia virus reverse transcriptase Descriptor: DNA (5'-D(*CP*TP*(JSP)P*(1W5)P*(1W5)P*(1WA)P*(IGU)P*(JSP))-3'), DNA (5'-D(P*(IGU)P*(JSP)P*(1W5)P*(1WA)P*(1WA)P*(IGU)P*AP*G)-3'), reverse transcriptase Authors: Georgiadis, M.M. Deposit date: 2022-05-12 Release date: 2023-05-17 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Alien DNA visualized at high resolution in A- and B-forms To Be Published
6M38	X-ray structure of a Drosophila dopamine transporter with subsiteB mutations (D121G/S426M) in S-duloxetine bound form Descriptor: (3S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine, Antibody fragment 9D5 heavy chain, Antibody fragment 9D5 light chain, ... Authors: Shabareesh, P, Mallela, A.K, Joseph, D, Penmatsa, A. Deposit date: 2020-03-02 Release date: 2021-02-17 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (3.001 Å) Cite: Structural basis of norepinephrine recognition and transport inhibition in neurotransmitter transporters. Nat Commun, 12, 2021
7WLW	X-ray structure of thermostabilized Drosophila dopamine transporter with GABA transporter1-like substitutions in the binding site, in complex with SKF89976a Descriptor: (3S)-1-(4,4-diphenylbut-3-enyl)piperidine-3-carboxylic acid, Antibody Fragment heavy chain, Antibody fragment light chain, ... Authors: Penmatsa, A, Joseph, D. Deposit date: 2022-01-13 Release date: 2022-06-29 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural insights into GABA transport inhibition using an engineered neurotransmitter transporter. Embo J., 41, 2022
6M3Z	X-ray structure of a Drosophila dopamine transporter with NET-like mutations (D121G/S426M/F471L) in milnacipran bound form Descriptor: (1R,2S)-2-(aminomethyl)-N,N-diethyl-1-phenyl-cyclopropane-1-carboxamide, Antibody fragment 9D5 Light chain, Antibody fragment 9D5 heavy chain, ... Authors: Shabareesh, P, Mallela, A.K, Joseph, D, Penmatsa, A. Deposit date: 2020-03-04 Release date: 2021-02-17 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (3.11 Å) Cite: Structural basis of norepinephrine recognition and transport inhibition in neurotransmitter transporters. Nat Commun, 12, 2021
8Q79	Structure of mBaoJin at pH 6.5 Descriptor: CHLORIDE ION, mBaoJin Authors: Samygina, V.R, Subach, O.M, Vlaskina, A.V, Nikolaeva, A.Y, Borshchevsky, V, Qin, W, Subach, F.V. Deposit date: 2023-08-15 Release date: 2023-12-27 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Bright and stable monomeric green fluorescent protein derived from StayGold. Nat.Methods, 21, 2024
6PG7	WDR5delta32 bound to (2-(3-methoxy-3-phenylpropyl)-1H-imidazol-4-yl)methanol Descriptor: DI(HYDROXYETHYL)ETHER, WD repeat-containing protein 5, {2-[(3S)-3-methoxy-3-phenylpropyl]-1H-imidazol-4-yl}methanol Authors: Dennis, M.L, Peat, T.S. Deposit date: 2019-06-24 Release date: 2019-12-11 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Fragment screening for a protein-protein interaction inhibitor to WDR5. Struct Dyn., 6, 2019
6VFM	Crystal structure of SpeG allosteric polyamine acetyltransferase from Bacillus thuringiensis Descriptor: Spermidine N1-acetyltransferase Authors: Tsimbalyuk, S, Shornikov, A, Le, V.T.B, Kuhn, M.L, Forwood, J.K. Deposit date: 2020-01-05 Release date: 2020-02-19 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.67 Å) Cite: SpeG polyamine acetyltransferase enzyme from Bacillus thuringiensis forms a dodecameric structure and exhibits high catalytic efficiency. J.Struct.Biol., 210, 2020
6M0Z	X-ray structure of Drosophila dopamine transporter with NET-like mutations (D121G/S426M/F471L) in L-norepinephrine bound form Descriptor: Antibody fragment (Fab) 9D5 Light chain, Antibody fragment (Fab) 9D5 heavy chain, CHLORIDE ION, ... Authors: Shabareesh, P, Mallela, A.K, Joseph, D, Penmatsa, A. Deposit date: 2020-02-24 Release date: 2021-02-17 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.88 Å) Cite: Structural basis of norepinephrine recognition and transport inhibition in neurotransmitter transporters. Nat Commun, 12, 2021
8PP2	Binary crystal structure of positively supercharged ferritin variant Ftn(pos) and native(K86Q) human heavy chain ferritin (Mg formate condition) Descriptor: FE (III) ION, Ferritin heavy chain, N-terminally processed, ... Authors: Lang, L, Beck, T. Deposit date: 2023-07-06 Release date: 2023-12-27 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.001 Å) Cite: Assembly Requirements for the Construction of Large-Scale Binary Protein Structures. Biomacromolecules, 25, 2024
6M47	X-ray structure of a Drosophila dopamine transporter with NET-like mutations (D121G/S426M/F471L) in tramadol bound form Descriptor: (1S,2S)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexan-1-ol, Antibody fragment 9D5 light chain, Antibody fragment Heavy chain, ... Authors: Shabareesh, P, Mallela, A.K, Joseph, D, Penmatsa, A. Deposit date: 2020-03-05 Release date: 2021-02-17 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (3.252 Å) Cite: Structural basis of norepinephrine recognition and transport inhibition in neurotransmitter transporters. Nat Commun, 12, 2021
7OBD	Crystal structure of 14-3-3 sigma in complex with Phosphorylated and Farnesylated Rnd3 peptide and stabilizer Fusicoccin-A Descriptor: 14-3-3 protein sigma, CHLORIDE ION, FARNESYL, ... Authors: Centorrino, F, Andlovic, B, Ottmann, C. Deposit date: 2021-04-21 Release date: 2022-05-04 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: IFN alpha primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization. Cell Chem Biol, 2023
6PGD	WDR5delta32 bound to peptidomimetic Descriptor: N-acetyl-L-alanyl-5-[5-(hydroxymethyl)-1H-imidazol-2-yl]-L-norvalyl-L-valinamide, SULFATE ION, WD repeat-containing protein 5 Authors: Dennis, M.L, Peat, T.S. Deposit date: 2019-06-24 Release date: 2019-12-11 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Fragment screening for a protein-protein interaction inhibitor to WDR5. Struct Dyn., 6, 2019
7WGD	X-ray structure of thermostabilized Drosophila dopamine transporter with GABA transporter1-like substitutions in the binding site, in substrate-free form. Descriptor: Antibody fragment (9D5) Light Chain, Antibody fragment (9D5) heavy chain, CHLORIDE ION, ... Authors: Joseph, D, Penmatsa, A. Deposit date: 2021-12-28 Release date: 2022-06-29 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structural insights into GABA transport inhibition using an engineered neurotransmitter transporter. Embo J., 41, 2022
6VFP	Crystal structure of human protocadherin 1 EC1-EC4 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Protocadherin-1, ... Authors: Brasch, J, Harrison, O.J, Shapiro, L. Deposit date: 2020-01-06 Release date: 2020-03-11 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Family-wide Structural and Biophysical Analysis of Binding Interactions among Non-clustered delta-Protocadherins. Cell Rep, 30, 2020
6LTB	Crystal Structure of Nonribosomal peptide synthetases (NRPS), FmoA3 (S1046A)-AMPPNP bound form Descriptor: Nonribosomal peptide synthetase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER Authors: Senda, T, Harada, A. Deposit date: 2020-01-22 Release date: 2021-02-24 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Structural and Functional Analyses of the Tridomain-Nonribosomal Peptide Synthetase FmoA3 for 4-Methyloxazoline Ring Formation. Angew.Chem.Int.Ed.Engl., 60, 2021

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