7SZD
Crystal Structure Analysis of human PRPK complex with a compound
Summary for 7SZD
Entry DOI | 10.2210/pdb7szd/pdb |
Descriptor | EKC/KEOPS complex subunit TP53RK, EKC/KEOPS complex subunit TPRKB, 2-[(3R)-3-methyl-2,6-dioxopiperidin-3-yl]-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylic acid, ... (4 entities in total) |
Functional Keywords | protein kinase, p53, immunomodulatory drugs, imids, transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 97302.27 |
Authors | Seo, H.-S.,Dhe-Paganon, S. (deposition date: 2021-11-27, release date: 2022-12-14, Last modification date: 2024-02-07) |
Primary citation | Seo, H.-S.,Mizutani, T.,Hideshima, T.,Vangos, N.E.,Zhang, T.,Anderson, K.C.,Gray, N.S.,Dhe-Paganon, S. Development of PRPK Directed Phthalimides Biorxiv, 2021 Cited by DOI: 10.1101/2021.11.30.469594PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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