6UY4

Crystal structure of dihydroorotate dehydrogenase from Schistosoma mansoni

Summary for 6UY4

• Entry DOI: 10.2210/pdb6uy4/pdb
• Related: 6UOY
• Descriptor: Dihydroorotate dehydrogenase, 2-[(4-fluorophenyl)amino]-3-hydroxynaphthalene-1,4-dione, GLYCEROL, ... (5 entities in total)
• Functional Keywords: smdhodh, class 2 dihydroorotate dehydrogenase, schistosoma mansoni, flavoprotein, oxidoreductase-inhibitor complex, oxidoreductase/inhibitor
• Biological source: Schistosoma mansoni (Blood fluke)
• Total number of polymer chains: 1
• Total formula weight: 42450.15

Authors

Mori, R.M.,Zapata, L.C.C.,Nonato, M.C. (deposition date: 2019-11-11, release date: 2020-05-27, Last modification date: 2023-10-11)

• Primary citation: de Mori, R.M.,Aleixo, M.A.A.,Zapata, L.C.C.,Calil, F.A.,Emery, F.S.,Nonato, M.C.; Structural basis for the function and inhibition of dihydroorotate dehydrogenase from Schistosoma mansoni.; Febs J., 288:930-944, 2021; PubMed: 32428996; DOI: 10.1111/febs.15367

Experimental method

X-RAY DIFFRACTION (2.796 Å)