7WLW
X-ray structure of thermostabilized Drosophila dopamine transporter with GABA transporter1-like substitutions in the binding site, in complex with SKF89976a
Summary for 7WLW
Entry DOI | 10.2210/pdb7wlw/pdb |
Related | 7WGD 7WGT |
Descriptor | Sodium-dependent dopamine transporter, Antibody fragment light chain, Antibody Fragment heavy chain, ... (10 entities in total) |
Functional Keywords | neurotransmitter transporter, membrane protein |
Biological source | Drosophila melanogaster (fruit fly) More |
Total number of polymer chains | 3 |
Total formula weight | 109178.86 |
Authors | Penmatsa, A.,Joseph, D. (deposition date: 2022-01-13, release date: 2022-06-29, Last modification date: 2023-11-29) |
Primary citation | Joseph, D.,Nayak, S.R.,Penmatsa, A. Structural insights into GABA transport inhibition using an engineered neurotransmitter transporter. Embo J., 41:e110735-e110735, 2022 Cited by PubMed: 35796008DOI: 10.15252/embj.2022110735 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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