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1PLS
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BU of 1pls by Molmil
SOLUTION STRUCTURE OF A PLECKSTRIN HOMOLOGY DOMAIN
Descriptor: PLECKSTRIN HOMOLOGY DOMAIN
Authors:Yoon, H.S, Hajduk, P.J, Petros, A.M, Olejniczak, E.T, Meadows, R.P, Fesik, S.W.
Deposit date:1994-05-03
Release date:1995-06-03
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of a pleckstrin-homology domain.
Nature, 369, 1994
6R6H
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BU of 6r6h by Molmil
Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome
Descriptor: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ...
Authors:Morris, E.P, Faull, S.V, Lau, A.M.C, Politis, A, Beuron, F, Cronin, N.
Deposit date:2019-03-27
Release date:2019-08-28
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (8.4 Å)
Cite:Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome.
Nat Commun, 10, 2019
1JLT
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BU of 1jlt by Molmil
Vipoxin Complex
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, PHOSPHOLIPASE A2, ...
Authors:Banumathi, S, Rajashankar, K.R, Notzel, C, Aleksiev, B, Singh, T.P, Genov, N, Betzel, C.
Deposit date:2001-07-16
Release date:2001-10-31
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure of the neurotoxic complex vipoxin at 1.4 A resolution.
Acta Crystallogr.,Sect.D, 57, 2001
5EXA
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BU of 5exa by Molmil
Small-molecule stabilization of the 14-3-3/Gab2 PPI interface
Descriptor: 14-3-3 protein zeta/delta, BENZOIC ACID, Fusicoccin A-THF derivative, ...
Authors:Bier, D, Ottmann, C.
Deposit date:2015-11-23
Release date:2016-05-04
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Small-Molecule Stabilization of the 14-3-3/Gab2 Protein-Protein Interaction (PPI) Interface.
Chemmedchem, 11, 2016
1W2N
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BU of 1w2n by Molmil
Deacetoxycephalosporin C synthase (with a N-terminal his-tag) in complex with Fe(II) and ampicillin
Descriptor: (2S,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID, DEACETOXYCEPHALOSPORIN C SYNTHASE, FE (III) ION
Authors:Oster, L.M, Terwisscha Van Scheltinga, A.C, Valegard, K, Mackenzie Hose, A, Dubus, A, Hajdu, J, Andersson, I.
Deposit date:2004-07-07
Release date:2004-09-30
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Conformational Flexibility of the C Terminus with Implications for Substrate Binding and Catalysis Revealed in a New Crystal Form of Deacetoxycephalosporin C Synthase
J.Mol.Biol., 343, 2004
5EWZ
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BU of 5ewz by Molmil
Small-molecule stabilization of the 14-3-3/Gab2 PPI interface
Descriptor: 14-3-3 protein zeta/delta, BENZOIC ACID, GRB2-associated-binding protein 2
Authors:Bier, D, Ottmann, C.
Deposit date:2015-11-23
Release date:2016-05-04
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Small-Molecule Stabilization of the 14-3-3/Gab2 Protein-Protein Interaction (PPI) Interface.
Chemmedchem, 11, 2016
5ETJ
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BU of 5etj by Molmil
Crystal structure of purine nucleoside phosphorylase (E258D, L261A) mutant from human complexed with DADMe-ImmG and phosphate
Descriptor: 2-amino-7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-1-yl]methyl}-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one, PHOSPHATE ION, Purine nucleoside phosphorylase
Authors:Cameron, S.A, Suarez, J, Schramm, V.L, Almo, S.C.
Deposit date:2015-11-17
Release date:2016-09-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Modulating Enzyme Catalysis through Mutations Designed to Alter Rapid Protein Dynamics.
J.Am.Chem.Soc., 138, 2016
1JAU
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BU of 1jau by Molmil
NMR Solution Structure of the Trp-Rich Peptide of HIV gp41 Bound to DPC Micelles
Descriptor: TRANSMEMBRANE GLYCOPROTEIN (GP41)
Authors:Schibli, D.J, Montelaro, R.C, Vogel, H.J.
Deposit date:2001-05-31
Release date:2001-10-17
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:The membrane-proximal tryptophan-rich region of the HIV glycoprotein, gp41, forms a well-defined helix in dodecylphosphocholine micelles.
Biochemistry, 40, 2001
1NYY
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BU of 1nyy by Molmil
Crystal Structure of the complex between M182T mutant of TEM-1 and a boronic acid inhibitor (105)
Descriptor: Beta-lactamase TEM, N-[5-METHYL-3-O-TOLYL-ISOXAZOLE-4-CARBOXYLIC ACID AMIDE] BORONIC ACID
Authors:Wang, X, Minasov, G, Blazquez, J, Caselli, E, Prati, F, Shoichet, B.K.
Deposit date:2003-02-14
Release date:2003-08-26
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Recognition and resistance in TEM beta-lactamase
Biochemistry, 42, 2003
1JJZ
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REFINED STRUCTURE AND DISULFIDE PAIRING OF THE KALATA B1 PEPTIDE
Descriptor: Kalata-B4
Authors:Skjeldal, L, Gran, L, Sletten, K, Volkman, B.F.
Deposit date:2001-07-10
Release date:2002-06-12
Last modified:2020-08-12
Method:SOLUTION NMR
Cite:Refined structure and metal binding site of the kalata B1 peptide.
Arch.Biochem.Biophys., 399, 2002
8EVA
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BU of 8eva by Molmil
Cryo-EM structure of cGMP bound truncated human CNGA3/CNGB3 channel in lipid nanodisc, transition state 2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel alpha-3, ...
Authors:Hu, Z, Yang, J.
Deposit date:2022-10-20
Release date:2023-08-09
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Conformational trajectory of allosteric gating of the human cone photoreceptor cyclic nucleotide-gated channel.
Nat Commun, 14, 2023
8EVB
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BU of 8evb by Molmil
Cryo-EM structure of cGMP bound truncated human CNGA3/CNGB3 channel in lipid nanodisc, pre-open state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel alpha-3, ...
Authors:Hu, Z, Yang, J.
Deposit date:2022-10-20
Release date:2023-08-09
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Conformational trajectory of allosteric gating of the human cone photoreceptor cyclic nucleotide-gated channel.
Nat Commun, 14, 2023
8EV9
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BU of 8ev9 by Molmil
Cryo-EM structure of cGMP bound truncated human CNGA3/CNGB3 channel in lipid nanodisc, transition state 1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel alpha-3, ...
Authors:Hu, Z, Yang, J.
Deposit date:2022-10-20
Release date:2023-08-09
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Conformational trajectory of allosteric gating of the human cone photoreceptor cyclic nucleotide-gated channel.
Nat Commun, 14, 2023
8EV8
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BU of 8ev8 by Molmil
Cryo-EM structure of cGMP bound truncated human CNGA3/CNGB3 channel in lipid nanodisc, closed state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel alpha-3, ...
Authors:Hu, Z, Yang, J.
Deposit date:2022-10-20
Release date:2023-08-09
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:Conformational trajectory of allosteric gating of the human cone photoreceptor cyclic nucleotide-gated channel.
Nat Commun, 14, 2023
8EVC
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BU of 8evc by Molmil
Cryo-EM structure of cGMP bound truncated human CNGA3/CNGB3 channel in lipid nanodisc, open state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel alpha-3, ...
Authors:Hu, Z, Yang, J.
Deposit date:2022-10-20
Release date:2023-08-09
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Conformational trajectory of allosteric gating of the human cone photoreceptor cyclic nucleotide-gated channel.
Nat Commun, 14, 2023
1JE3
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BU of 1je3 by Molmil
Solution Structure of EC005 from Escherichia coli
Descriptor: HYPOTHETICAL 8.6 KDA PROTEIN IN AMYA-FLIE INTERGENIC REGION
Authors:Yee, A, Gutierrez, P, Kozlov, G, Denisov, A, Gehring, K, Arrowsmith, C.
Deposit date:2001-06-15
Release date:2002-03-06
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:An NMR approach to structural proteomics.
Proc.Natl.Acad.Sci.USA, 99, 2002
3DQN
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BU of 3dqn by Molmil
Structure of the Yellow Fluorescent Protein Citrine Frozen at 500 Atmospheres: Structure 3 in a Series of 26 High Pressure Structures
Descriptor: Green fluorescent protein
Authors:Barstow, B, Kim, C.U.
Deposit date:2008-07-09
Release date:2008-09-23
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Alteration of citrine structure by hydrostatic pressure explains the accompanying spectral shift.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3EJ0
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BU of 3ej0 by Molmil
Crystal structure of inorganic pyrophosphatase from burkholderia pseudomallei with bound N-(pyridin-3-ylmethyl) aniline, H32 crystal form
Descriptor: Inorganic pyrophosphatase, N-(pyridin-3-ylmethyl)aniline
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2008-09-17
Release date:2008-09-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:The role of medical structural genomics in discovering new drugs for infectious diseases.
PLoS Comput Biol, 5, 2009
4KH6
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BU of 4kh6 by Molmil
Toxoplasma gondii NTPDase1 C258S/C268S E493G crystallized with Mg and AMPNP
Descriptor: 5'-O-[(R)-hydroxy(phosphonoamino)phosphoryl]adenosine, MAGNESIUM ION, Nucleoside-triphosphatase 2
Authors:Krug, U, Totzauer, R, Strater, N.
Deposit date:2013-04-30
Release date:2013-11-06
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The ATP/ADP substrate specificity switch between Toxoplasma gondii NTPDase1 and NTPDase3 is caused by an altered mode of binding of the substrate base.
Chembiochem, 14, 2013
1NZR
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BU of 1nzr by Molmil
CRYSTAL STRUCTURE OF THE AZURIN MUTANT NICKEL-TRP48MET FROM PSEUDOMONAS AERUGINOSA AT 2.2 ANGSTROMS RESOLUTION
Descriptor: AZURIN, NICKEL (II) ION, NITRATE ION
Authors:Tsai, L.-C, Sjolin, L, Langer, V, Bonander, N, Karlsson, B.G, Vanngard, T, Hammann, C, Nar, H.
Deposit date:1994-12-09
Release date:1995-02-27
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the azurin mutant nickel-Trp48Met from Pseudomonas aeruginosa at 2.2 A resolution.
Acta Crystallogr.,Sect.D, 51, 1995
1RG9
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BU of 1rg9 by Molmil
S-Adenosylmethionine synthetase complexed with SAM and PPNP
Descriptor: (DIPHOSPHONO)AMINOPHOSPHONIC ACID, MAGNESIUM ION, POTASSIUM ION, ...
Authors:Komoto, J, Yamada, T, Takata, Y, Markham, G.D, Takusagawa, F.
Deposit date:2003-11-11
Release date:2004-03-02
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the S-adenosylmethionine synthetase ternary complex: a novel catalytic mechanism of s-adenosylmethionine synthesis from ATP and MET.
Biochemistry, 43, 2004
1ZKM
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BU of 1zkm by Molmil
Structural Analysis of Escherichia Coli ThiF
Descriptor: Adenylyltransferase thiF, ZINC ION
Authors:Duda, D.M, Walden, H, Sfondouris, J, Schulman, B.A.
Deposit date:2005-05-03
Release date:2005-06-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural Analysis of Escherichia Coli ThiF.
J.Mol.Biol., 349, 2005
3CJB
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BU of 3cjb by Molmil
Actin dimer cross-linked by V. cholerae MARTX toxin and complexed with Gelsolin-segment 1
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Sawaya, M.R, Kudryashov, D.S, Pashkov, I, Reisler, E, Yeates, T.O.
Deposit date:2008-03-12
Release date:2008-03-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Connecting actin monomers by iso-peptide bond is a toxicity mechanism of the Vibrio cholerae MARTX toxin.
Proc.Natl.Acad.Sci.USA, 105, 2008
5KMG
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BU of 5kmg by Molmil
Near-atomic cryo-EM structure of PRC1 bound to the microtubule
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kellogg, E.H, Howes, S, Ti, S.-C, Ramirez-Aportela, E, Kapoor, T.M, Chacon, P, Nogales, E.
Deposit date:2016-06-27
Release date:2016-08-03
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Near-atomic cryo-EM structure of PRC1 bound to the microtubule.
Proc.Natl.Acad.Sci.USA, 113, 2016
6SGB
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mt-SSU assemblosome of Trypanosoma brucei
Descriptor: 9S rRNA, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Saurer, M, Ramrath, D.J.F, Niemann, M, Calderaro, S, Prange, C, Mattei, S, Scaiola, A, Leitner, A, Bieri, P, Horn, E.K, Leibundgut, M, Boehringer, D, Schneider, A, Ban, N.
Deposit date:2019-08-03
Release date:2019-09-25
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Mitoribosomal small subunit biogenesis in trypanosomes involves an extensive assembly machinery.
Science, 365, 2019

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