1NYY
Crystal Structure of the complex between M182T mutant of TEM-1 and a boronic acid inhibitor (105)
Summary for 1NYY
Entry DOI | 10.2210/pdb1nyy/pdb |
Related | 1NXY 1NY0 1NYM |
Descriptor | Beta-lactamase TEM, N-[5-METHYL-3-O-TOLYL-ISOXAZOLE-4-CARBOXYLIC ACID AMIDE] BORONIC ACID (3 entities in total) |
Functional Keywords | antibiotic resistance, beta-lactamase, acylation transition-state analog, hydrolase |
Biological source | Escherichia coli |
Total number of polymer chains | 1 |
Total formula weight | 29206.40 |
Authors | Wang, X.,Minasov, G.,Blazquez, J.,Caselli, E.,Prati, F.,Shoichet, B.K. (deposition date: 2003-02-14, release date: 2003-08-26, Last modification date: 2023-08-16) |
Primary citation | Wang, X.,Minasov, G.,Blazquez, J.,Caselli, E.,Prati, F.,Shoichet, B.K. Recognition and resistance in TEM beta-lactamase Biochemistry, 42:8434-8444, 2003 Cited by PubMed: 12859188DOI: 10.1021/bi034242y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
Download full validation report