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6ZMO	SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complex Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. Deposit date: 2020-07-03 Release date: 2020-08-19 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020
6ZU9	Structure of a yeast ABCE1-bound 48S initiation complex Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... Authors: Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. Deposit date: 2020-07-22 Release date: 2020-10-28 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (6.2 Å) Cite: A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes. Embo J., 40, 2021
6ZXF	Cryo-EM structure of a late human pre-40S ribosomal subunit - State G Descriptor: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... Authors: Ameismeier, M, Zemp, I, van den Heuvel, J, Thoms, M, Berninghausen, O, Kutay, U, Beckmann, R. Deposit date: 2020-07-29 Release date: 2020-12-02 Last modified: 2020-12-09 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural basis for the final steps of human 40S ribosome maturation. Nature, 587, 2020
6ZMI	SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complex Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. Deposit date: 2020-07-02 Release date: 2020-08-19 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020
6ZVI	Mbf1-ribosome complex Descriptor: 18S rRNA, 40S ribosomal protein S0-A, 40S ribosomal protein S10-A, ... Authors: Best, K.M, Denk, T, Cheng, J, Thoms, M, Berninghausen, O, Beckmann, R. Deposit date: 2020-07-24 Release date: 2020-09-09 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3 Å) Cite: EDF1 coordinates cellular responses to ribosome collisions. Elife, 9, 2020
5A2Q	Structure of the HCV IRES bound to the human ribosome Descriptor: 18S RRNA, HCV IRES, MAGNESIUM ION, ... Authors: Quade, N, Leiundgut, M, Boehringer, D, Heuvel, J.v.d, Ban, N. Deposit date: 2015-05-21 Release date: 2015-07-15 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Cryo-Em Structure of Hepatitis C Virus Ires Bound to the Human Ribosome at 3.9 Angstrom Resolution Nat.Commun., 6, 2015
6LQS	Cryo-EM structure of 90S small subunit preribosomes in transition states (State D) Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S pre-rRNA, 40S ribosomal protein S1-A, ... Authors: Du, Y, Ye, K. Deposit date: 2020-01-14 Release date: 2020-09-16 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states. Science, 369, 2020
6LQR	Cryo-EM structure of 90S small subunit preribosomes in transition states (State C) Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S pre-rRNA, 40S ribosomal protein S1-A, ... Authors: Du, Y, Ye, K. Deposit date: 2020-01-14 Release date: 2020-09-16 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (8.6 Å) Cite: Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states. Science, 369, 2020
6LQV	Cryo-EM structure of 90S small subunit preribosomes in transition states (State C1) Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S pre-rRNA, 40S ribosomal protein S11-A, ... Authors: Du, Y, Ye, K. Deposit date: 2020-01-14 Release date: 2020-09-16 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (4.8 Å) Cite: Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states. Science, 369, 2020
5TGA	Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCA-Pro Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), ... Authors: Melnikov, S, Mailliot, J. Deposit date: 2016-09-27 Release date: 2016-11-23 Last modified: 2016-12-14 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Molecular insights into protein synthesis with proline residues. EMBO Rep., 17, 2016
5TGM	Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCA-Pro Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), ... Authors: Melnikov, S, Mailliot, J, Yusupov, M. Deposit date: 2016-09-28 Release date: 2017-01-18 Last modified: 2022-12-07 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Molecular insights into protein synthesis with proline residues. EMBO Rep., 17, 2016
5TBW	Crystal structure of chlorolissoclimide bound to the yeast 80S ribosome Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... Authors: Konst, Z.A, Szklarski, A.R, Pellegrino, S, Michalak, S.E, Meyer, M, Zanette, C, Cencic, R, Nam, S, Horne, D.A, Pelletier, J, Mobley, D.L, Yusupova, G, Yusupov, M, Vanderwal, C.D. Deposit date: 2016-09-13 Release date: 2017-07-26 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3 Å) Cite: Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides. Nat Chem, 9, 2017
5T2C	CryoEM structure of the human ribosome at 3.6 Angstrom resolution Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... Authors: Zhang, X, Lai, M, Zhou, Z.H. Deposit date: 2016-08-23 Release date: 2017-01-25 Last modified: 2023-08-16 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes. Nat Commun, 7, 2016
5TZS	Architecture of the yeast small subunit processome Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S ribosomal RNA, 3' domain-associated, ... Authors: Chaker-Margot, M, Barandun, J, Hunziker, M, Klinge, S. Deposit date: 2016-11-22 Release date: 2016-12-21 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (5.1 Å) Cite: Architecture of the yeast small subunit processome. Science, 355, 2017
5UKD	PH INFLUENCES FLUORIDE COORDINATION NUMBER OF THE ALFX PHOSPHORYL TRANSFER TRANSITION STATE ANALOG Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CYTIDINE-5'-MONOPHOSPHATE, ... Authors: Schlichting, I, Reinstein, J. Deposit date: 1999-04-18 Release date: 1999-08-14 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: pH influences fluoride coordination number of the AlFx phosphoryl transfer transition state analog. Nat.Struct.Biol., 6, 1999
5VYC	Crystal structure of the human 40S ribosomal subunit in complex with DENR-MCT-1. Descriptor: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... Authors: Lomakin, I.B, Stolboushkina, E.A, Vaidya, A.T, Garber, M.B, Dmitriev, S.E, Steitz, T.A. Deposit date: 2017-05-24 Release date: 2017-07-19 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (6 Å) Cite: Crystal Structure of the Human Ribosome in Complex with DENR-MCT-1. Cell Rep, 20, 2017
5T2A	CryoEM structure of the Leishmania donovani 80S ribosome at 2.9 Angstrom resolution Descriptor: 18S rRNA, 5.8S rRNA, 5S rRNA, ... Authors: Zhang, X, Lai, M, Zhou, Z.H. Deposit date: 2016-08-23 Release date: 2017-01-25 Last modified: 2018-07-18 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes. Nat Commun, 7, 2016
1M0E	ZEBULARINE: A NOVEL DNA METHYLATION INHIBITOR THAT FORMS A COVALENT COMPLEX WITH DNA METHYLTRANSFERASE Descriptor: 5'-D(P*CP*CP*AP*TP*GP*CP*GP*CP*TP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*AP*GP*(Z)P*GP*CP*AP*TP*GP*G)-3', Modification methylase HhaI, ... Authors: Zhou, L, Cheng, X, Connolly, B.A, Dickman, M.J, Hurd, P.J, Hornby, D.P. Deposit date: 2002-06-12 Release date: 2002-09-18 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: ZEBULARINE: A NOVEL DNA METHYLATION INHIBITOR THAT FORMS A COVALENT COMPLEX WITH DNA METHYLTRANSFERASES J.MOL.BIOL., 321, 2002
6AZ1	Cryo-EM structure of the small subunit of Leishmania ribosome bound to paromomycin Descriptor: E-site tRNA, LACK1, MAGNESIUM ION, ... Authors: Shalev-Benami, M, Zhang, Y, Rozenberg, H, Matzov, D, Zimmerman, E, Bashan, A, Jaffe, C.L, Yonath, A, Skiniotis, G. Deposit date: 2017-09-09 Release date: 2017-12-06 Last modified: 2019-07-03 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Atomic resolution snapshot of Leishmania ribosome inhibition by the aminoglycoside paromomycin. Nat Commun, 8, 2017
1NJJ	Crystal structure determination of T. brucei ornithine decarboxylase bound to D-ornithine and to G418 Descriptor: GENETICIN, N~2~-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-D-ORNITHINE, ornithine decarboxylase Authors: Jackson, L.K, Goldsmith, E.J, Phillips, M.A. Deposit date: 2002-12-31 Release date: 2003-08-26 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.45 Å) Cite: X-ray Structure Determination of Trypanosoma brucei Ornithine Decarboxylase Bound to D-Ornithine and to G418: INSIGHTS INTO SUBSTRATE BINDING AND ODC CONFORMATIONAL FLEXIBILITY. J.Biol.Chem., 278, 2003
1KS8	The structure of Endoglucanase from termite, Nasutitermes takasagoensis, at pH 2.5. Descriptor: Endo-b-1,4-glucanase, SULFATE ION Authors: Khademi, S, Guarino, L.A, Watanabe, H, Tokuda, G, Meyer, E.F. Deposit date: 2002-01-11 Release date: 2003-01-21 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Structure of an endoglucanase from termite, Nasutitermes takasagoensis. Acta Crystallogr.,Sect.D, 58, 2002
6DGI	The crystal structure of D-alanyl-alanine synthetase A from Vibrio cholerae O1 biovar eltor str. N16961 Descriptor: ACETATE ION, D-alanine--D-alanine ligase, GLYCEROL, ... Authors: Tan, K, Zhou, M, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2018-05-17 Release date: 2018-05-30 Last modified: 2019-12-18 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The crystal structure of D-alanyl-alanine synthetase A from Vibrio cholerae O1 biovar eltor str. N16961 To Be Published
6D9J	Mammalian 80S ribosome with a double translocated CrPV-IRES, P-sitetRNA and eRF1. Descriptor: 18S rRNA, 28S rRNA, 5.8S rRNA, ... Authors: Pisareva, V.P, Pisarev, A.V, Fernandez, I.S. Deposit date: 2018-04-30 Release date: 2018-06-06 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Dual tRNA mimicry in the Cricket Paralysis Virus IRES uncovers an unexpected similarity with the Hepatitis C Virus IRES. Elife, 7, 2018
1P3J	Adenylate Kinase from Bacillus subtilis Descriptor: Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, MAGNESIUM ION, ... Authors: Bae, E, Phillips Jr, G.N. Deposit date: 2003-04-17 Release date: 2004-05-04 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structures and analysis of highly homologous psychrophilic, mesophilic, and thermophilic adenylate kinases. J.Biol.Chem., 279, 2004
1MHT	COVALENT TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE, DNA AND S-ADENOSYL-L-HOMOCYSTEINE Descriptor: DNA (5'-D(*TP*GP*AP*TP*AP*GP*(C36)P*GP*CP*TP*AP*TP*C)-3'), DNA (5'-D(P*GP*AP*TP*AP*GP*(C36)P*GP*CP*TP*AP*TP*C)-3'), PROTEIN (HHAI METHYLTRANSFERASE), ... Authors: Cheng, X. Deposit date: 1994-12-08 Release date: 1995-06-03 Last modified: 2018-04-18 Method: X-RAY DIFFRACTION (2.6 Å) Cite: HhaI methyltransferase flips its target base out of the DNA helix. Cell(Cambridge,Mass.), 76, 1994

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