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3ZIR
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BU of 3zir by Molmil
minor-site specific NLS (B141)
Descriptor: B141NLS, IMPORTIN SUBUNIT ALPHA-2
Authors:Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B.
Deposit date:2013-01-10
Release date:2013-08-21
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Distinctive Conformation of Minor Site-Specific Nuclear Localization Signals Bound to Importin-Alpha
Traffic, 14, 2013
4MF2
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BU of 4mf2 by Molmil
Structure of human DNA polymerase beta complexed with O6MG as the template base in a 1-nucleotide gapped DNA
Descriptor: DNA polymerase beta, SODIUM ION, synthetic downstream primer, ...
Authors:Koag, M.C, Min, K, Monzingo, A.F, Lee, S.
Deposit date:2013-08-27
Release date:2014-04-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta.
J.Am.Chem.Soc., 136, 2014
6QC2
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BU of 6qc2 by Molmil
Ovine respiratory supercomplex I+III2 open class 2
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Acyl carrier protein, ...
Authors:Letts, J.A, Sazanov, L.A.
Deposit date:2018-12-26
Release date:2019-08-21
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk.
Mol.Cell, 75, 2019
6QC6
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BU of 6qc6 by Molmil
Ovine respiratory complex I FRC open class 1
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Acyl carrier protein, ...
Authors:Letts, J.A, Sazanov, L.A.
Deposit date:2018-12-27
Release date:2019-08-21
Last modified:2019-10-02
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk.
Mol.Cell, 75, 2019
6QC9
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BU of 6qc9 by Molmil
Ovine respiratory complex I FRC open class 4
Descriptor: Acyl carrier protein, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ...
Authors:Letts, J.A, Sazanov, L.A.
Deposit date:2018-12-27
Release date:2019-08-21
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (5.7 Å)
Cite:Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk.
Mol.Cell, 75, 2019
6QCA
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BU of 6qca by Molmil
Ovine respiratory complex I FRC open class 5
Descriptor: Acyl carrier protein, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ...
Authors:Letts, J.A, Sazanov, L.A.
Deposit date:2018-12-27
Release date:2019-08-21
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk.
Mol.Cell, 75, 2019
6QC3
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BU of 6qc3 by Molmil
Ovine respiratory supercomplex I+III2 open class 1
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Acyl carrier protein, ...
Authors:Letts, J.A, Sazanov, L.A.
Deposit date:2018-12-26
Release date:2019-08-21
Last modified:2021-06-02
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk.
Mol.Cell, 75, 2019
1PRH
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BU of 1prh by Molmil
THE X-RAY CRYSTAL STRUCTURE OF THE MEMBRANE PROTEIN PROSTAGLANDIN H2 SYNTHASE-1
Descriptor: PROSTAGLANDIN H2 SYNTHASE-1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Picot, D, Loll, P.J, Garavito, R.M.
Deposit date:1994-03-07
Release date:1995-03-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1.
Nature, 367, 1994
1CMK
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BU of 1cmk by Molmil
CRYSTAL STRUCTURES OF THE MYRISTYLATED CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE REVEAL OPEN AND CLOSED CONFORMATIONS
Descriptor: IODIDE ION, MYRISTIC ACID, cAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT, ...
Authors:Zheng, J, Knighton, D.R, Xuong, N.-H, Taylor, S.S, Sowadski, J.M, Ten Eyck, L.F.
Deposit date:1993-11-18
Release date:1994-05-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structures of the myristylated catalytic subunit of cAMP-dependent protein kinase reveal open and closed conformations.
Protein Sci., 2, 1993
8OO0
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BU of 8oo0 by Molmil
Chaetomium thermophilum Methionine Aminopeptidase 2 autoproteolysis product at the 80S ribosome
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S0, ...
Authors:Klein, M.A, Wild, K, Kisonaite, M, Sinning, I.
Deposit date:2023-04-04
Release date:2024-02-21
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Methionine aminopeptidase 2 and its autoproteolysis product have different binding sites on the ribosome.
Nat Commun, 15, 2024
4NXZ
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BU of 4nxz by Molmil
DNA polymerase beta with O6mG in the template base opposite to incoming non-hydrolyzable TTP with manganese in the active site
Descriptor: 5'-D(*CP*CP*GP*AP*CP*(6OG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ...
Authors:Koag, M.-C, Min, K, Monzingo, A.F, Lee, S.
Deposit date:2013-12-09
Release date:2014-04-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.557 Å)
Cite:Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta.
J.Am.Chem.Soc., 136, 2014
4NY8
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BU of 4ny8 by Molmil
DNA polymerase beta with O6mG in the template base opposite to incoming non-hydrolyzable CTP with manganese in the active site
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, 5'-D(*CP*CP*GP*AP*CP*(6OG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3', ...
Authors:Koag, M.-C, Min, K, Monzingo, A.F, Lee, S.
Deposit date:2013-12-10
Release date:2014-04-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.246 Å)
Cite:Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta.
J.Am.Chem.Soc., 136, 2014
3KMJ
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BU of 3kmj by Molmil
Crystal structure of vSET under condition B
Descriptor: A612L protein, SULFATE ION
Authors:Wei, H, Zhou, M.M.
Deposit date:2009-11-10
Release date:2010-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Dimerization of a viral SET protein endows its function.
Proc.Natl.Acad.Sci.USA, 107, 2010
3ZIQ
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BU of 3ziq by Molmil
minor-site specific NLS (B6)
Descriptor: B6NLS, IMPORTIN SUBUNIT ALPHA-2
Authors:Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B.
Deposit date:2013-01-10
Release date:2013-08-21
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Distinctive Conformation of Minor Site-Specific Nuclear Localization Signals Bound to Importin-Alpha
Traffic, 14, 2013
3ZIP
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BU of 3zip by Molmil
minor-site specific NLS (A58)
Descriptor: A58NLS, IMPORTIN SUBUNIT ALPHA-2
Authors:Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B.
Deposit date:2013-01-10
Release date:2013-08-21
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Distinctive Conformation of Minor Site-Specific Nuclear Localization Signals Bound to Importin-Alpha
Traffic, 14, 2013
3RCB
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BU of 3rcb by Molmil
Crystal structure of the K102E mutant of KijD10, a 3-ketoreductase from Actinomadura kijaniata in complex with TDP-benzene and NADP
Descriptor: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phenoxy)phosphoryl]oxy}phosphoryl]thymidine, CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Holden, H.M, Kubiak, R.L.
Deposit date:2011-03-30
Release date:2011-06-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Combined Structural and Functional Investigation of a C-3''-Ketoreductase Involved in the Biosynthesis of dTDP-l-Digitoxose.
Biochemistry, 50, 2011
3KMA
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BU of 3kma by Molmil
Crystal Structure of vSET under Condition A
Descriptor: A612L protein, CHLORIDE ION, GLYCEROL, ...
Authors:Wei, H, Zhou, M.M.
Deposit date:2009-11-10
Release date:2010-11-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Dimerization of a viral SET protein endows its function.
Proc.Natl.Acad.Sci.USA, 107, 2010
5W6K
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BU of 5w6k by Molmil
Structure of mutant Taq Polymerase incorporating unnatural base pairs Z:P
Descriptor: (1R)-1-[6-amino-5-(dihydroxyamino)-2-hydroxypyridin-3-yl]-1,4-anhydro-2-deoxy-5-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-D-erythro-pentitol, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), DNA (5'-D(P*(1WA)P*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ...
Authors:Singh, I, Georgiadis, M.M.
Deposit date:2017-06-16
Release date:2018-07-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.339 Å)
Cite:Snapshots of an evolved DNA polymerase pre- and post-incorporation of an unnatural nucleotide.
Nucleic Acids Res., 46, 2018
4ACH
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BU of 4ach by Molmil
GSK3b in complex with inhibitor
Descriptor: 3-AMINO-N-(3-METHOXYPROPYL)-6-{4-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}PYRAZINE-2-CARBOXAMIDE, GLYCOGEN SYNTHASE KINASE-3 BETA
Authors:Xue, Y, Ormo, M.
Deposit date:2011-12-15
Release date:2012-05-16
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Discovery of novel potent and highly selective glycogen synthase kinase-3 beta (GSK3 beta ) inhibitors for Alzheimer's disease: design, synthesis, and characterization of pyrazines.
J. Med. Chem., 55, 2012
4ACD
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BU of 4acd by Molmil
GSK3b in complex with inhibitor
Descriptor: 3-AMINO-6-{4-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-N-PYRIDIN-3-YLPYRAZINE-2-CARBOXAMIDE, GLYCOGEN SYNTHASE KINASE-3 BETA
Authors:Xue, Y, Ormo, M.
Deposit date:2011-12-15
Release date:2012-05-16
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Discovery of novel potent and highly selective glycogen synthase kinase-3 beta (GSK3 beta ) inhibitors for Alzheimer's disease: design, synthesis, and characterization of pyrazines.
J. Med. Chem., 55, 2012
4JWE
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BU of 4jwe by Molmil
Crystal structure of the substrate binding domain of E.coli DnaK in complex with sheep Bac7(1-21)
Descriptor: Cathelicidin-3, Chaperone protein DnaK, SULFATE ION
Authors:Zahn, M, Straeter, N.
Deposit date:2013-03-27
Release date:2013-11-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural Identification of DnaK Binding Sites within Bovine and Sheep Bactenecin Bac7.
Protein Pept.Lett., 21, 2014
4JWI
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BU of 4jwi by Molmil
Crystal structure of the substrate binding domain of E.coli DnaK in complex with sheep Bac7(35-43)
Descriptor: Cathelicidin-3, Chaperone protein DnaK, SULFATE ION
Authors:Zahn, M, Straeter, N.
Deposit date:2013-03-27
Release date:2013-11-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Identification of DnaK Binding Sites within Bovine and Sheep Bactenecin Bac7.
Protein Pept.Lett., 21, 2014
1E5A
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BU of 1e5a by Molmil
Structure of human transthyretin complexed with bromophenols: a new mode of binding
Descriptor: 2,4,6-TRIBROMOPHENOL, TRANSTHYRETIN
Authors:Ghosh, M, Meerts, I.A.T.M, Cook, A, Bergman, A, Brouwer, A, Johnson, L.N.
Deposit date:2000-07-20
Release date:2000-08-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of Human Transthyretin Complexed with Bromophenols : A New Mode of Binding
Acta Crystallogr.,Sect.D, 56, 2000
9ICE
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BU of 9ice by Molmil
DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DATP (1 MILLIMOLAR) AND CUCL2 (0.1 MILLIMOLAR)
Descriptor: DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3'), PROTEIN (DNA POLYMERASE BETA (E.C.2.7.7.7)), ...
Authors:Pelletier, H, Sawaya, M.R.
Deposit date:1995-12-15
Release date:1996-11-15
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Characterization of the metal ion binding helix-hairpin-helix motifs in human DNA polymerase beta by X-ray structural analysis.
Biochemistry, 35, 1996
8XG2
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BU of 8xg2 by Molmil
The structure of HLA-A/Pep14
Descriptor: Beta-2-microglobulin, HLA class I heavy chain, Spike protein S1
Authors:Zhang, J.N, Yue, C, Liu, J.
Deposit date:2023-12-14
Release date:2024-07-10
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Uncommon P1 Anchor-featured Viral T Cell Epitope Preference within HLA-A*2601 and HLA-A*0101 Individuals.
Immunohorizons, 8, 2024

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