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8F2H
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BU of 8f2h by Molmil
Wild type P53 dimer structure from human cancer cells
Descriptor: Cellular tumor antigen p53
Authors:Solares, M, Kelly, D.F.
Deposit date:2022-11-08
Release date:2022-11-23
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:High-Resolution Imaging of Human Cancer Proteins Using Microprocessor Materials.
Chembiochem, 23, 2022
6TLJ
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BU of 6tlj by Molmil
Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Mitotic checkpoint complex (APC/C-MCC) at 3.8 angstrom resolution
Descriptor: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
Authors:Alfieri, C, Barford, D.
Deposit date:2019-12-02
Release date:2020-02-19
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:A unique binding mode of Nek2A to the APC/C allows its ubiquitination during prometaphase.
Embo Rep., 21, 2020
2Y4W
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BU of 2y4w by Molmil
Solution structure of human ubiquitin conjugating enzyme Rad6b
Descriptor: UBIQUITIN-CONJUGATING ENZYME E2 B
Authors:Huang, A, Hibbert, R.G, deJong, R.N, Das, D, Sixma, T.K, Boelens, R.
Deposit date:2011-01-11
Release date:2011-05-11
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Symmetry and Asymmetry of the Ring-Ring Dimer of Rad18
J.Mol.Biol., 410, 2011
4Q5H
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BU of 4q5h by Molmil
Shigella Effector Kinase OspG bound to AMPPNP and E2-Ub UbcH7-Ub Conjugate
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Polyubiquitin, ...
Authors:Cygler, M, Grishin, A.M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2014-04-16
Release date:2014-07-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Structural Basis for the Inhibition of Host Protein Ubiquitination by Shigella Effector Kinase OspG.
Structure, 22, 2014
4Q5E
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BU of 4q5e by Molmil
Shigella Effector Kinase OspG bound to E2-Ub UbcH7-Ub Conjugate
Descriptor: Polyubiquitin, Protein kinase OspG, Ubiquitin-conjugating enzyme E2 L3
Authors:Cygler, M, Grishin, A.M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2014-04-16
Release date:2014-07-02
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.869 Å)
Cite:Structural Basis for the Inhibition of Host Protein Ubiquitination by Shigella Effector Kinase OspG.
Structure, 22, 2014
8ODR
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BU of 8odr by Molmil
Mimetic of UBC9-SUMO1
Descriptor: SULFATE ION, SUMO-conjugating enzyme UBC9, Small ubiquitin-related modifier 1
Authors:Coste, F, Goffinont, S, Suskiewicz, M.J.
Deposit date:2023-03-09
Release date:2023-06-07
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural insights into the regulation of the human E2∼SUMO conjugate through analysis of its stable mimetic.
J.Biol.Chem., 299, 2023
2GJD
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BU of 2gjd by Molmil
Distinct functional domains of Ubc9 dictate cell survival and resistance to genotoxic stress
Descriptor: Ubiquitin-conjugating enzyme E2-18 kDa
Authors:van Waardenburg, R.C, Duda, D.M, Lancaster, C.S, Schulman, B.A, Bjornsti, M.A.
Deposit date:2006-03-30
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Distinct functional domains of ubc9 dictate cell survival and resistance to genotoxic stress.
Mol.Cell.Biol., 26, 2006
6LQS
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BU of 6lqs by Molmil
Cryo-EM structure of 90S small subunit preribosomes in transition states (State D)
Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S pre-rRNA, 40S ribosomal protein S1-A, ...
Authors:Du, Y, Ye, K.
Deposit date:2020-01-14
Release date:2020-09-16
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states.
Science, 369, 2020
2EWN
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BU of 2ewn by Molmil
Ecoli Biotin Repressor with co-repressor analog
Descriptor: ((2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDROFURAN-2-YL)METHYL 5-((3AS,4S,6AR)-2-OXO-HEXAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-4-YL)PENTYL HYDROGEN PHOSPHATE, BirA bifunctional protein
Authors:Wood, Z.A, Weaver, L.H, Matthews, B.W.
Deposit date:2005-11-04
Release date:2006-02-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Co-repressor Induced Order and Biotin Repressor Dimerization: A Case for Divergent Followed by Convergent Evolution.
J.Mol.Biol., 357, 2006
7BBF
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BU of 7bbf by Molmil
Crystal structure of ubiquitin charged Ube2N (Ube2N~Ub) in complex with Ube2V2
Descriptor: Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2
Authors:Kiss, L, Neuhaus, D, James, L.C.
Deposit date:2020-12-17
Release date:2021-01-27
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:RING domains act as both substrate and enzyme in a catalytic arrangement to drive self-anchored ubiquitination.
Nat Commun, 12, 2021
4Y1L
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BU of 4y1l by Molmil
Ubc9 Homodimer The Missing Link in Poly-SUMO Chain Formation
Descriptor: RWD domain-containing protein 3, SUMO-conjugating enzyme UBC9
Authors:Aileen, Y.A, Ambaye, N.D, Li, Y.J, Vega, R, Bzymek, K, Williams, J.C, Hu, W, Chen, Y.
Deposit date:2015-02-08
Release date:2015-05-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:RWD Domain as an E2 (Ubc9)-Interaction Module.
J.Biol.Chem., 290, 2015
6NIF
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BU of 6nif by Molmil
crystal structure of human REV7-RAN complex
Descriptor: hREV7, GTP-binding nuclear protein Ran, hREV3 fusion
Authors:Wang, X, Pertz, L, Hua, D.P, Zhang, T.Q, Listovsky, T, Xie, W.
Deposit date:2018-12-27
Release date:2019-09-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.002 Å)
Cite:REV7 has a dynamic adaptor region to accommodate small GTPase RAN/ShigellaIpaB ligands, and its activity is regulated by the RanGTP/GDP switch.
J.Biol.Chem., 294, 2019
4DHZ
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BU of 4dhz by Molmil
The structure of h/ceOTUB1-ubiquitin aldehyde-UBC13~Ub
Descriptor: Ubiquitin, Ubiquitin aldehyde, Ubiquitin thioesterase otubain-like, ...
Authors:Wiener, R, Zhang, X, Wang, T, Wolberger, C.
Deposit date:2012-01-30
Release date:2012-02-22
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:The mechanism of OTUB1-mediated inhibition of ubiquitination.
Nature, 483, 2012
3C6O
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BU of 3c6o by Molmil
Small molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling
Descriptor: (2S)-2-(1H-indol-3-yl)hexanoic acid, INOSITOL HEXAKISPHOSPHATE, SKP1-like protein 1A, ...
Authors:Tan, X.
Deposit date:2008-02-04
Release date:2008-04-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Small-molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3C6P
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BU of 3c6p by Molmil
Small molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling
Descriptor: (2S)-2-(1H-indol-3-yl)pentanoic acid, INOSITOL HEXAKISPHOSPHATE, SKP1-like protein 1A, ...
Authors:Tan, X.
Deposit date:2008-02-04
Release date:2008-04-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Small-molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling.
Proc.Natl.Acad.Sci.Usa, 105, 2008
6Y6X
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BU of 6y6x by Molmil
Tetracenomycin X bound to the human ribosome
Descriptor: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Buschauer, R, Cheng, J, Berninghausen, O, Beckmann, R, Wilson, D.N.
Deposit date:2020-02-27
Release date:2020-07-08
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Tetracenomycin X inhibits translation by binding within the ribosomal exit tunnel.
Nat.Chem.Biol., 16, 2020
3C6N
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BU of 3c6n by Molmil
Small molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling
Descriptor: (2S)-8-[(tert-butoxycarbonyl)amino]-2-(1H-indol-3-yl)octanoic acid, INOSITOL HEXAKISPHOSPHATE, SKP1-like protein 1A, ...
Authors:Tan, X, Zheng, N, Hayashi, K.
Deposit date:2008-02-04
Release date:2008-04-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Small-molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling.
Proc.Natl.Acad.Sci.Usa, 105, 2008
4WID
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BU of 4wid by Molmil
Crystal structure of the immediate-early 1 protein (IE1) at 2.31 angstrom (tetragonal form after crystal dehydration)
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, RhUL123
Authors:Klingl, S, Scherer, M, Sevvana, M, Muller, Y.A, Stamminger, T.
Deposit date:2014-09-25
Release date:2014-10-29
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Crystal Structure of Cytomegalovirus IE1 Protein Reveals Targeting of TRIM Family Member PML via Coiled-Coil Interactions.
Plos Pathog., 10, 2014
8GYM
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BU of 8gym by Molmil
Cryo-EM structure of Tetrahymena thermophila respiratory mega-complex MC IV2+(I+III2+II)2
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ...
Authors:Wu, M.C, Hu, Y.Q, Han, F.Z, Zhou, L.
Deposit date:2022-09-23
Release date:2023-06-14
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Structures of Tetrahymena thermophila respiratory megacomplexes on the tubular mitochondrial cristae.
Nat Commun, 14, 2023
4YE8
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BU of 4ye8 by Molmil
The crystal structure of the Y57H mutant of human GlnRS
Descriptor: Glutamine--tRNA ligase
Authors:Ognjenovic, J, Wu, J, Ling, J, Simonovic, M.
Deposit date:2015-02-23
Release date:2016-02-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The crystal structure of human GlnRS provides basis for the development of neurological disorders.
Nucleic Acids Res., 44, 2016
4RQW
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BU of 4rqw by Molmil
Crystal structure of Myc3 N-terminal JAZ-binding domain [44-238] from Arabidopsis
Descriptor: CALCIUM ION, Transcription factor MYC3
Authors:Ke, J, Zhang, F, Zhou, X.E, Brunzelle, J, Zhou, M, Xu, H.E, Melcher, K, He, S.Y.
Deposit date:2014-11-05
Release date:2015-08-12
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
4RRU
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BU of 4rru by Molmil
Myc3 N-terminal JAZ-binding domain[5-242] from arabidopsis
Descriptor: CALCIUM ION, Transcription factor MYC3
Authors:Ke, J, Zhang, F, Zhou, X.E, Brunzelle, J.S, Zhou, M, Xu, H.E, Melcher, K, He, S.Y.
Deposit date:2014-11-06
Release date:2015-08-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
4RS9
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BU of 4rs9 by Molmil
Structure of Myc3 N-terminal JAZ-binding domain [44-238] in complex with Jas motif of JAZ9
Descriptor: Protein TIFY 7, Transcription factor MYC3
Authors:Ke, J, Zhang, F, Zhou, X.E, Brunzelle, J.S, Zhou, M, Xu, H.E, Melcher, K, He, S.Y.
Deposit date:2014-11-07
Release date:2015-08-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
4YE9
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BU of 4ye9 by Molmil
The crystal structure of the G45V mutant of human GlnRS
Descriptor: Glutamine--tRNA ligase
Authors:Ognjenovic, J, Wu, J, Ling, J, Simonovic, M.
Deposit date:2015-02-23
Release date:2016-02-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The crystal structure of human GlnRS provides basis for the development of neurological disorders.
Nucleic Acids Res., 44, 2016
4YE6
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BU of 4ye6 by Molmil
The crystal structure of the intact human GlnRS
Descriptor: Glutamine--tRNA ligase
Authors:Ognjenovic, J, Wu, J, Ling, J, Simonovic, M.
Deposit date:2015-02-23
Release date:2016-02-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The crystal structure of human GlnRS provides basis for the development of neurological disorders.
Nucleic Acids Res., 44, 2016

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