2EWN

Ecoli Biotin Repressor with co-repressor analog

Summary for 2EWN

• Entry DOI: 10.2210/pdb2ewn/pdb
• Related: 1bia 1bib 1hxd
• Descriptor: BirA bifunctional protein, ((2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDROFURAN-2-YL)METHYL 5-((3AS,4S,6AR)-2-OXO-HEXAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-4-YL)PENTYL HYDROGEN PHOSPHATE (3 entities in total)
• Functional Keywords: helix-turn-helix, disorder-to-order transition, biotin, ligase, transcription
• Biological source: Escherichia coli
• Total number of polymer chains: 2
• Total formula weight: 71822.90

Authors

Wood, Z.A.,Weaver, L.H.,Matthews, B.W. (deposition date: 2005-11-04, release date: 2006-02-21, Last modification date: 2023-08-23)

• Primary citation: Wood, Z.A.,Weaver, L.H.,Brown, P.H.,Beckett, D.,Matthews, B.W.; Co-repressor Induced Order and Biotin Repressor Dimerization: A Case for Divergent Followed by Convergent Evolution.; J.Mol.Biol., 357:509-523, 2006; PubMed: 16438984; DOI: 10.1016/j.jmb.2005.12.066

Experimental method

X-RAY DIFFRACTION (2.8 Å)