PDB: 127 resultsInfo pagesStatus searchChemie searchBIRD

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3JRW	Phosphorylated BC domain of ACC2 Descriptor: Acetyl-CoA carboxylase 2 Authors: Cho, Y.S, Lee, J.I, Shin, D, Kim, H.T, Lee, T.G, Heo, Y.S. Deposit date: 2009-09-09 Release date: 2010-01-12 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Molecular mechanism for the regulation of human ACC2 through phosphorylation by AMPK Biochem.Biophys.Res.Commun., 391, 2010
8HZ4	The tetrameric structure of biotin carboxylase from Chloroflexus aurantiacus in complex with bicarbonate Descriptor: Biotin carboxylase Authors: Shen, J, Wu, W, Xu, X. Deposit date: 2023-01-08 Release date: 2024-01-10 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (3.2 Å) Cite: The tetrameric structure of biotin carboxylase from Chloroflexus aurantiacus in complex with bicarbonate To be published
8HZ5	The homodimer of a biotin carboxylase isoform from chloroflexus aurantiacus Descriptor: Biotin carboxylase Authors: Shen, J, Wu, W, Xu, X. Deposit date: 2023-01-08 Release date: 2024-01-10 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (3 Å) Cite: The homodimer of a biotin carboxylase isoform from chloroflexus aurantiacus To be published
8JAK	Human MCC in MCCU state Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial, ... Authors: Liu, D.S, Su, J.Y, Tian, X.Y. Deposit date: 2023-05-06 Release date: 2024-05-15 Method: ELECTRON MICROSCOPY (2.52 Å) Cite: Human MCC in BCCP-BCS state To Be Published
8JAW	Human MCC in MCCD state Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial, ... Authors: Liu, D.S, Su, J.Y, Tian, X.Y. Deposit date: 2023-05-07 Release date: 2024-05-15 Method: ELECTRON MICROSCOPY (2.51 Å) Cite: Human MCC in BCCP-CTS state To Be Published
8J4Z	Human 3-methylcrotonyl-CoA carboxylase in BCCP-CTS state with substrate Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial, ... Authors: Liu, D.S, Su, J.Y. Deposit date: 2023-04-21 Release date: 2024-04-24 Method: ELECTRON MICROSCOPY (2.73 Å) Cite: Human 3-methylcrotonyl-CoA carboxylase in BCCP-CTS state with substrate To Be Published
8J7O	Human pyruvate carboxylase in BCCP-CTS state without BC Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Pyruvate carboxylase, mitochondrial Authors: Liu, D.S, Su, J.Y. Deposit date: 2023-04-27 Release date: 2024-05-08 Method: ELECTRON MICROSCOPY (3.83 Å) Cite: Human pyruvate carboxylase To Be Published
8J99	Human 3-methylcrotonyl-CoA carboxylase in BCS-mcoa state Descriptor: Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial, Methylcrotonoyl-CoA carboxylase subunit alpha, ... Authors: Liu, D.S, Su, J.Y. Deposit date: 2023-05-02 Release date: 2024-05-08 Method: ELECTRON MICROSCOPY (2.87 Å) Cite: Human 3-methylcrotonyl-CoA carboxylase in BCS-mcoa state To Be Published
8J78	Human 3-methylcrotonyl-CoA carboxylase in BCCP-H2 state Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial, ... Authors: Liu, D.S, Su, J.Y. Deposit date: 2023-04-27 Release date: 2024-05-08 Method: ELECTRON MICROSCOPY (3.88 Å) Cite: Human 3-methylcrotonyl-CoA carboxylase in BCCP-H2 state To Be Published
8J7D	Human 3-methylcrotonyl-CoA carboxylase in BCCP-H1 state Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial, ... Authors: Liu, D.S, Su, J.Y. Deposit date: 2023-04-27 Release date: 2024-05-08 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Human 3-methylcrotonyl-CoA carboxylase in BCCP-H1 state To Be Published
8PN7	Engineered glycolyl-CoA carboxylase (G20R variant) with bound CoA Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, Propionyl-CoA carboxylase alpha subunit, ... Authors: Zarzycki, J, Marchal, D.G, Schulz, L, Prinz, S, Erb, T.J. Deposit date: 2023-06-30 Release date: 2023-11-29 Last modified: 2023-12-27 Method: ELECTRON MICROSCOPY (2.03 Å) Cite: Machine Learning-Supported Enzyme Engineering toward Improved CO 2 -Fixation of Glycolyl-CoA Carboxylase. Acs Synth Biol, 12, 2023
8PN8	Engineered glycolyl-CoA carboxylase (L100N variant) with bound CoA Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, Propionyl-CoA carboxylase alpha subunit, ... Authors: Zarzycki, J, Marchal, D.G, Schulz, L, Prinz, S, Erb, T.J. Deposit date: 2023-06-30 Release date: 2023-11-29 Last modified: 2023-12-27 Method: ELECTRON MICROSCOPY (2.31 Å) Cite: Machine Learning-Supported Enzyme Engineering toward Improved CO 2 -Fixation of Glycolyl-CoA Carboxylase. Acs Synth Biol, 12, 2023
2QF7	Crystal structure of a complete multifunctional pyruvate carboxylase from Rhizobium etli Descriptor: CHLORIDE ION, COENZYME A, FORMIC ACID, ... Authors: St Maurice, M, Surinya, K.H, Rayment, I. Deposit date: 2007-06-27 Release date: 2007-09-04 Last modified: 2012-02-15 Method: X-RAY DIFFRACTION (2 Å) Cite: Domain architecture of pyruvate carboxylase, a biotin-dependent multifunctional enzyme Science, 317, 2007
2V59	CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E.COLI IN COMPLEX WITH POTENT INHIBITOR 2 Descriptor: 6-(2,6-DIMETHOXYPHENYL)PYRIDO[2,3-D]PYRIMIDINE-2,7-DIAMINE, BIOTIN CARBOXYLASE Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-10-02 Release date: 2009-01-13 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.4 Å) Cite: A Class of Selective Antibacterials Derived from a Protein Kinase Inhibitor Pharmacophore. Proc.Natl.Acad.Sci.USA, 106, 2009
2V58	CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E.COLI IN COMPLEX WITH POTENT INHIBITOR 1 Descriptor: 6-(2,6-dibromophenyl)pyrido[2,3-d]pyrimidine-2,7-diamine, BIOTIN CARBOXYLASE, CHLORIDE ION Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-10-02 Release date: 2009-01-13 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.1 Å) Cite: A Class of Selective Antibacterials Derived from a Protein Kinase Inhibitor Pharmacophore. Proc.Natl.Acad.Sci.USA, 106, 2009
2W6Z	Crystal structure of Biotin carboxylase from E. coli in complex with the 3-(3-Methyl-but-2-enyl)-3H-purin-6-ylamine fragment Descriptor: 3-(3-methylbut-2-en-1-yl)-3H-purin-6-amine, BIOTIN CARBOXYLASE, CHLORIDE ION Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-12-19 Release date: 2009-05-19 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
2W6M	Crystal structure of Biotin carboxylase from E. coli in complex with amino-oxazole fragment series Descriptor: (2-AMINO-1,3-OXAZOL-5-YL)-(3-BROMOPHENYL)METHANONE, BIOTIN CARBOXYLASE, CHLORIDE ION Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-12-18 Release date: 2009-05-19 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
2W6P	Crystal structure of Biotin carboxylase from E. coli in complex with 5-Methyl-6-phenyl-quinazoline-2,4-diamine Descriptor: 5-methyl-6-phenylquinazoline-2,4-diamine, ACETYL-COA CARBOXYLASE Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-12-18 Release date: 2009-05-19 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
2W70	Crystal structure of Biotin carboxylase from E. coli in complex with the amino-thiazole-pyrimidine fragment Descriptor: 4-(2-amino-1,3-thiazol-4-yl)pyrimidin-2-amine, BIOTIN CARBOXYLASE, CHLORIDE ION Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-12-19 Release date: 2009-05-19 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.77 Å) Cite: Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
2V5A	CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E.COLI IN COMPLEX WITH POTENT INHIBITOR 3 Descriptor: 7-(2,5-dihydropyrrol-1-yl)-6-phenyl-pyrido[6,5-d]pyrimidin-2-amine, BIOTIN CARBOXYLASE, CHLORIDE ION Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-10-02 Release date: 2009-01-13 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.31 Å) Cite: A Class of Selective Antibacterials Derived from a Protein Kinase Inhibitor Pharmacophore. Proc.Natl.Acad.Sci.USA, 106, 2009
2W6N	Crystal structure of Biotin carboxylase from E. coli in complex with amino-oxazole fragment series Descriptor: 2-AMINO-N,N-BIS(PHENYLMETHYL)-1,3-OXAZOLE-5-CARBOXAMIDE, BIOTIN CARBOXYLASE, CHLORIDE ION Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-12-18 Release date: 2009-05-19 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.87 Å) Cite: Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
2VPQ	Crystal structure of biotin carboxylase from S. aureus complexed with AMPPNP Descriptor: ACETYL-COA CARBOXYLASE, CHLORIDE ION, MAGNESIUM ION, ... Authors: Mochalkin, I. Deposit date: 2008-03-03 Release date: 2008-09-09 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase. Protein Sci., 17, 2008
2VQD	Crystal Structure of Biotin Carboxylase from Pseudomonas aeruginosa complexed with AMPCP Descriptor: BIOTIN CARBOXYLASE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... Authors: Mochalkin, I. Deposit date: 2008-03-13 Release date: 2008-09-09 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.41 Å) Cite: Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase. Protein Sci., 17, 2008
2VR1	Crystal structure of Biotin carboxylase from E. coli in complex with ATP analog, ADPCF2P. Descriptor: BIOTIN CARBOXYLASE, CHLORIDE ION, PHOSPHODIFLUOROMETHYLPHOSPHONIC ACID-ADENYLATE ESTER Authors: Mochalkin, I, Waldrop, G.L. Deposit date: 2008-03-24 Release date: 2008-09-09 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase. Protein Sci., 17, 2008
2W6O	Crystal structure of Biotin carboxylase from E. coli in complex with 4-Amino-7,7-dimethyl-7,8-dihydro-quinazolinone fragment Descriptor: 4-amino-7,7-dimethyl-7,8-dihydroquinazolin-5(6H)-one, BIOTIN CARBOXYLASE, CHLORIDE ION Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-12-18 Release date: 2009-05-19 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009

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