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8CIZ	DNA-polymerase sliding clamp (DnaN) from Escherichia coli in complex with Mycoplanecin A. Descriptor: Beta sliding clamp, Mycoplanecin A Authors: Fu, C, Liu, Y, Walt, C, Bader, C, Rasheed, S, Lukat, P, Neuber, M, Blankenfeldt, W, Kalinina, O, Mueller, R. Deposit date: 2023-02-11 Release date: 2023-11-29 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.27 Å) Cite: Elucidation of unusual biosynthesis and DnaN-targeting mode of action of potent anti-tuberculosis antibiotics Mycoplanecins. Nat Commun, 15, 2024
7AZ7	DNA polymerase sliding clamp from Escherichia coli with peptide 37 bound Descriptor: Beta sliding clamp, FORMIC ACID, PENTAETHYLENE GLYCOL, ... Authors: Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. Deposit date: 2020-11-16 Release date: 2021-12-01 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. J.Med.Chem., 64, 2021
7AZ6	DNA polymerase sliding clamp from Escherichia coli with peptide 36 bound Descriptor: ACETATE ION, Beta sliding clamp, CHLORIDE ION, ... Authors: Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. Deposit date: 2020-11-16 Release date: 2021-12-01 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. J.Med.Chem., 64, 2021
7AZ8	DNA polymerase sliding clamp from Escherichia coli with peptide 43 bound Descriptor: Beta sliding clamp, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... Authors: Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. Deposit date: 2020-11-16 Release date: 2021-12-01 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.61 Å) Cite: Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. J.Med.Chem., 64, 2021
7AZE	DNA polymerase sliding clamp from Escherichia coli with peptide 18 bound Descriptor: Beta sliding clamp, GLYCEROL, MALONATE ION, ... Authors: Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. Deposit date: 2020-11-16 Release date: 2021-12-01 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.82 Å) Cite: Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. J.Med.Chem., 64, 2021
7AZD	DNA polymerase sliding clamp from Escherichia coli with peptide 20 bound Descriptor: Beta sliding clamp, DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, ... Authors: Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. Deposit date: 2020-11-16 Release date: 2021-12-01 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.19 Å) Cite: Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. J.Med.Chem., 64, 2021
7AZL	DNA polymerase sliding clamp from Escherichia coli with peptide 38 bound Descriptor: Beta sliding clamp, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... Authors: Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. Deposit date: 2020-11-16 Release date: 2021-12-01 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.42 Å) Cite: Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. J.Med.Chem., 64, 2021
7AZ5	DNA polymerase sliding clamp from Escherichia coli with peptide 47 bound Descriptor: Beta sliding clamp, DI(HYDROXYETHYL)ETHER, Peptide 47, ... Authors: Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. Deposit date: 2020-11-16 Release date: 2021-12-01 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.87 Å) Cite: Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. J.Med.Chem., 64, 2021
7AZF	DNA polymerase sliding clamp from Escherichia coli with peptide 8 bound Descriptor: Beta sliding clamp, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... Authors: Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. Deposit date: 2020-11-16 Release date: 2021-12-01 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. J.Med.Chem., 64, 2021
7AZK	DNA polymerase sliding clamp from Escherichia coli with peptide 35 bound Descriptor: Beta sliding clamp, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... Authors: Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. Deposit date: 2020-11-16 Release date: 2021-12-01 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. J.Med.Chem., 64, 2021
7AZC	DNA polymerase sliding clamp from Escherichia coli with peptide 22 bound Descriptor: Beta sliding clamp, GLYCEROL, Peptide 22 Authors: Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. Deposit date: 2020-11-16 Release date: 2021-12-01 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.77 Å) Cite: Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. J.Med.Chem., 64, 2021
7AZG	DNA polymerase sliding clamp from Escherichia coli with peptide 4 bound Descriptor: Beta sliding clamp, Peptide 4 Authors: Monsarrat, C, Compain, G, Andre, C, Martiel, I, Engilberge, S, Olieric, V, Wolff, P, Brillet, K, Landolfo, M, Silva da Veiga, C, Wagner, J, Guichard, G, Burnouf, D.Y. Deposit date: 2020-11-16 Release date: 2021-12-01 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.92 Å) Cite: Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. J.Med.Chem., 64, 2021
4K3Q	E. coli sliding clamp in complex with AcQLDAF Descriptor: (ACE)QLDAF, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-04-11 Release date: 2013-05-01 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp J.Med.Chem., 56, 2013
4K74	The UmuC subunit of the E. coli DNA polymerase V shows a unique interaction with the beta-clamp processivity factor. Descriptor: DNA polymerase III subunit beta, UmuC peptide Authors: Patoli, A.A, Winter, J.A, Bunting, K.A. Deposit date: 2013-04-16 Release date: 2013-07-17 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The UmuC subunit of the E. coli DNA polymerase V shows a unique interaction with the beta-clamp processivity factor. Bmc Struct.Biol., 13, 2013
4K3L	E. coli sliding clamp in complex with AcLF dipeptide Descriptor: 1,2-ETHANEDIOL, ACETYL GROUP, CALCIUM ION, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-04-10 Release date: 2013-05-01 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp J.Med.Chem., 56, 2013
4K3R	E. coli sliding clamp in complex with AcQLDLA Descriptor: (ACE)QLDLA, CALCIUM ION, CHLORIDE ION, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-04-11 Release date: 2013-05-01 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.86 Å) Cite: Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp J.Med.Chem., 56, 2013
4K3S	E. coli sliding clamp in P1 crystal space group Descriptor: CALCIUM ION, DNA polymerase III subunit beta, O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-04-11 Release date: 2013-05-01 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp J.Med.Chem., 56, 2013
4K3P	E. coli sliding clamp in complex with AcQLALF Descriptor: (ACE)QLALF, 1,2-ETHANEDIOL, CALCIUM ION, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-04-11 Release date: 2013-05-01 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp J.Med.Chem., 56, 2013
4K3K	E. Coli sliding clamp in complex with (S)-2-(4-methylpentanamido)-3-phenylpropanoic acid Descriptor: CALCIUM ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-04-10 Release date: 2013-05-01 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp J.Med.Chem., 56, 2013
4K3M	E.coli sliding clamp in complex with AcALDLF peptide Descriptor: ALDLF, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-04-11 Release date: 2013-05-01 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp J.Med.Chem., 56, 2013
4K3O	E. coli sliding clamp in complex with AcQADLF Descriptor: (ACE)QADLF, 1,2-ETHANEDIOL, CALCIUM ION, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-04-11 Release date: 2013-05-01 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp J.Med.Chem., 56, 2013
4MJR	E. coli sliding clamp in complex with (S)-Carprofen Descriptor: (2S)-2-(6-chloro-9H-carbazol-2-yl)propanoic acid, CALCIUM ION, CHLORIDE ION, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-09-04 Release date: 2013-09-18 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.62 Å) Cite: DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs. Chem.Biol., 21, 2014
4MJP	E. coli sliding clamp in complex with (R)-Vedaprofen Descriptor: (2R)-2-(4-cyclohexylnaphthalen-1-yl)propanoic acid, CALCIUM ION, CHLORIDE ION, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-09-04 Release date: 2013-09-18 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.855 Å) Cite: DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs. Chem.Biol., 21, 2014
4MJQ	E. coli sliding clamp in complex with Bromfenac Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-09-04 Release date: 2013-09-18 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.73 Å) Cite: DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs. Chem.Biol., 21, 2014
4N96	E. coli sliding clamp in complex with 6-nitroindazole Descriptor: 6-NITROINDAZOLE, CALCIUM ION, CHLORIDE ION, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-10-19 Release date: 2013-11-06 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. J.Med.Chem., 57, 2014

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