7AZ7

DNA polymerase sliding clamp from Escherichia coli with peptide 37 bound

Summary for 7AZ7

Entry DOI	10.2210/pdb7az7/pdb
Descriptor	Beta sliding clamp, Peptide 37, FORMIC ACID, ... (5 entities in total)
Functional Keywords	antibacterial drug, dna binding protein
Biological source	Escherichia coli 2-427-07_S4_C3 More
Total number of polymer chains	2
Total formula weight	44042.13
Authors	Monsarrat, C.,Compain, G.,Andre, C.,Martiel, I.,Engilberge, S.,Olieric, V.,Wolff, P.,Brillet, K.,Landolfo, M.,Silva da Veiga, C.,Wagner, J.,Guichard, G.,Burnouf, D.Y. (deposition date: 2020-11-16, release date: 2021-12-01, Last modification date: 2024-01-31)
Primary citation	Monsarrat, C.,Compain, G.,Andre, C.,Engilberge, S.,Martiel, I.,Olieric, V.,Wolff, P.,Brillet, K.,Landolfo, M.,Silva da Veiga, C.,Wagner, J.,Guichard, G.,Burnouf, D.Y. Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. J.Med.Chem., 64:17063-17078, 2021 Cited by PubMed: 34806883 DOI: 10.1021/acs.jmedchem.1c00918 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation