7AZF

DNA polymerase sliding clamp from Escherichia coli with peptide 8 bound

Summary for 7AZF

• Entry DOI: 10.2210/pdb7azf/pdb
• Descriptor: Beta sliding clamp, Peptide 8, GLYCEROL, ... (5 entities in total)
• Functional Keywords: antibacterial drug, dna binding protein
• Biological source: Escherichia coli 2-427-07_S4_C3; More
• Total number of polymer chains: 8
• Total formula weight: 167141.13

Authors

Monsarrat, C.,Compain, G.,Andre, C.,Martiel, I.,Engilberge, S.,Olieric, V.,Wolff, P.,Brillet, K.,Landolfo, M.,Silva da Veiga, C.,Wagner, J.,Guichard, G.,Burnouf, D.Y. (deposition date: 2020-11-16, release date: 2021-12-01, Last modification date: 2024-02-07)

• Primary citation: Monsarrat, C.,Compain, G.,Andre, C.,Engilberge, S.,Martiel, I.,Olieric, V.,Wolff, P.,Brillet, K.,Landolfo, M.,Silva da Veiga, C.,Wagner, J.,Guichard, G.,Burnouf, D.Y.; Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp.; J.Med.Chem., 64:17063-17078, 2021; PubMed: 34806883; DOI: 10.1021/acs.jmedchem.1c00918

Experimental method

X-RAY DIFFRACTION (1.93 Å)