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1RVD
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H-RAS COMPLEXED WITH DIAMINOBENZOPHENONE-BETA,GAMMA-IMIDO-GTP
Descriptor: 3-AMINOBENZOPHENONE-4-YL-AMINOHYDROXYPHOSPHINYLAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, TRANSFORMING PROTEIN P21/H-RAS-1
Authors:Ahmadian, M.R, Zor, T, Vogt, D, Kabsch, W, Selinger, Z, Wittinghofer, A, Scheffzek, K.
Deposit date:1999-05-03
Release date:1999-05-28
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Guanosine triphosphatase stimulation of oncogenic Ras mutants.
Proc.Natl.Acad.Sci.USA, 96, 1999
1RYF
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BU of 1ryf by Molmil
Alternative Splicing of Rac1 Generates Rac1b, a Self-activating GTPase
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ras-related C3 botulinum toxin substrate 1 isoform Rac1b
Authors:Ahmadian, M.R, Fiegen, D.
Deposit date:2003-12-22
Release date:2004-01-27
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Alternative Splicing of Rac1 Generates Rac1b, a Self-activating GTPase
J.Biol.Chem., 279, 2004
1RYH
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Alternative Splicing of Rac1 Generates Rac1b, a Self-activating GTPase
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ras-related C3 botulinum toxin substrate 1 isoform Rac1b
Authors:Ahmadian, M.R, Fiegen, D.
Deposit date:2003-12-22
Release date:2004-01-27
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Alternative Splicing of Rac1 Generates Rac1b, a Self-activating GTPase
J.Biol.Chem., 279, 2004
1S1C
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BU of 1s1c by Molmil
Crystal structure of the complex between the human RhoA and Rho-binding domain of human ROCKI
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Rho-associated, ...
Authors:Dvorsky, R, Blumenstein, L, Vetter, I.R, Ahmadian, M.R.
Deposit date:2004-01-06
Release date:2004-02-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Insights into the Interaction of ROCKI with the Switch Regions of RhoA.
J.Biol.Chem., 279, 2004
1S8F
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Crystal structure of Rab9 complexed to GDP reveals a dimer with an active conformation of switch II
Descriptor: BENZOIC ACID, CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Wittmann, J.G, Rudolph, M.G.
Deposit date:2004-02-02
Release date:2004-06-11
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Crystal structure of Rab9 complexed to GDP reveals a dimer with an active conformation of switch II.
Febs Lett., 568, 2004
1T91
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crystal structure of human small GTPase Rab7(GTP)
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-7
Authors:Song, H, Hong, W, Wu, M, Wang, T.
Deposit date:2004-05-14
Release date:2005-05-17
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for recruitment of RILP by small GTPase Rab7.
Embo J., 24, 2005
1TU3
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Crystal Structure of Rab5 complex with Rabaptin5 C-terminal Domain
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Rab GTPase binding effector protein 1, ...
Authors:Zhu, G, Zhai, P, Liu, J, Terzyan, S, Li, G, Zhang, X.C.
Deposit date:2004-06-24
Release date:2004-10-05
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Structural basis of Rab5-Rabaptin5 interaction in endocytosis
Nat.Struct.Mol.Biol., 11, 2004
1TU4
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Crystal Structure of Rab5-GDP Complex
Descriptor: COBALT (II) ION, GUANOSINE-5'-DIPHOSPHATE, Ras-related protein Rab-5A, ...
Authors:Zhu, G, Zhai, P, Liu, J, Terzyan, S, Li, G, Zhang, X.C.
Deposit date:2004-06-24
Release date:2004-10-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of Rab5-Rabaptin5 interaction in endocytosis
Nat.Struct.Mol.Biol., 11, 2004
1TX4
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BU of 1tx4 by Molmil
RHO/RHOGAP/GDP(DOT)ALF4 COMPLEX
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, P50-RHOGAP, ...
Authors:Rittinger, K, Walker, P.A, Smerdon, S.J, Gamblin, S.J.
Deposit date:1997-07-29
Release date:1998-09-16
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transition-state analogue.
Nature, 389, 1997
1U8Y
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CRystal structures of Ral-GppNHp and Ral-GDP reveal two novel binding sites that are also present in Ras and Rap
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Ral-A
Authors:Nicely, N.I, Kosak, J, de Serrano, V, Mattos, C.
Deposit date:2004-08-09
Release date:2004-11-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal Structures of Ral-GppNHp and Ral-GDP Reveal Two Binding Sites that Are Also Present in Ras and Rap
Structure, 12, 2004
1U8Z
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Crystal structures of Ral-GppNHp and Ral-GDP reveal two novel binding sites that are also present in Ras and Rap
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Ral-A
Authors:Nicely, N.I, Kosak, J, de Serrano, V, Mattos, C.
Deposit date:2004-08-09
Release date:2004-11-23
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal Structures of Ral-GppNHp and Ral-GDP Reveal Two Binding Sites that Are Also Present in Ras and Rap
Structure, 12, 2004
1U90
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Crystal structures of Ral-GppNHp and Ral-GDP reveal two novel binding sites that are also present in Ras and Rap
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Ral-A
Authors:Nicely, N.I, Kosak, J, de Serrano, V, Mattos, C.
Deposit date:2004-08-09
Release date:2004-11-23
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of Ral-GppNHp and Ral-GDP Reveal Two Binding Sites that Are Also Present in Ras and Rap
Structure, 12, 2004
1UAD
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BU of 1uad by Molmil
Crystal structure of the RalA-GppNHp-Sec5 Ral-binding domain complex
Descriptor: Exocyst complex component Sec5, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Fukai, S, Matern, H.T, Scheller, R.H, Brunger, A.T.
Deposit date:2003-03-09
Release date:2003-07-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of the interaction between RalA and Sec5, a subunit of the Sec6/8 complex
EMBO J., 22, 2003
1UKV
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BU of 1ukv by Molmil
Structure of RabGDP-dissociation inhibitor in complex with prenylated YPT1 GTPase
Descriptor: GERAN-8-YL GERAN, GTP-binding protein YPT1, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Rak, A, Pylypenko, O, Durek, T, Watzke, A, Kushnir, S, Brunsveld, L, Waldmann, H, Goody, R.S, Alexandrov, K.
Deposit date:2003-09-01
Release date:2004-09-01
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of Rab GDP-dissociation inhibitor in complex with prenylated YPT1 GTPase
Science, 302, 2003
1VG0
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BU of 1vg0 by Molmil
The crystal structures of the REP-1 protein in complex with monoprenylated Rab7 protein
Descriptor: CHLORIDE ION, GERAN-8-YL GERAN, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Rak, A, Pylypenko, O, Niculae, A, Pyatkov, K, Goody, R.S, Alexandrov, K.
Deposit date:2004-04-22
Release date:2004-07-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the Rab7:REP-1 complex: insights into the mechanism of Rab prenylation and choroideremia disease
Cell(Cambridge,Mass.), 117, 2004
1VG1
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GDP-Bound Rab7
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-7
Authors:Rak, A, Pylypenko, O, Niculae, A, Pyatkov, K, Goody, R.S, Alexandrov, K.
Deposit date:2004-04-22
Release date:2004-07-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the Rab7:REP-1 complex: insights into the mechanism of Rab prenylation and choroideremia disease
Cell(Cambridge,Mass.), 117, 2004
1VG8
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BU of 1vg8 by Molmil
GPPNHP-Bound Rab7
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Rab-7
Authors:Rak, A, Pylypenko, O, Niculae, A, Pyatkov, K, Goody, R.S, Alexandrov, K.
Deposit date:2004-04-23
Release date:2004-07-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of the Rab7:REP-1 complex: insights into the mechanism of Rab prenylation and choroideremia disease
Cell(Cambridge,Mass.), 117, 2004
1VG9
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The crystal structures of the REP-1 protein in complex with C-terminally truncated Rab7 protein
Descriptor: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Rak, A, Pylypenko, O, Niculae, A, Pyatkov, K, Goody, R.S, Alexandrov, K.
Deposit date:2004-04-23
Release date:2004-07-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the Rab7:REP-1 complex: insights into the mechanism of Rab prenylation and choroideremia disease
Cell(Cambridge,Mass.), 117, 2004
1WA5
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BU of 1wa5 by Molmil
Structure of the Cse1:Imp-alpha:RanGTP complex
Descriptor: GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, Importin alpha re-exporter, ...
Authors:Stewart, M.
Deposit date:2004-10-23
Release date:2004-12-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the assembly of a nuclear export complex.
Nature, 432, 2004
1WMS
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BU of 1wms by Molmil
High resolution crystal structure of human Rab9 GTPase: a novel antiviral drug target
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Ras-related protein Rab-9A
Authors:Chen, L, DiGiammarino, E, Zhou, X.E, Wang, Y, Toh, D, Hodge, T.W, Meehan, E.J.
Deposit date:2004-07-16
Release date:2004-09-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:High resolution crystal structure of human Rab9 GTPase: A novel antiviral drug target
J.Biol.Chem., 279, 2004
1WQ1
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RAS-RASGAP COMPLEX
Descriptor: ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, H-RAS, ...
Authors:Scheffzek, K, Ahmadian, M.R, Kabsch, W, Wiesmueller, L, Lautwein, A, Schmitz, F, Wittinghofer, A.
Deposit date:1997-07-03
Release date:1998-07-15
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants.
Science, 277, 1997
1X1R
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Crystal structure of M-Ras in complex with GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein M-Ras
Authors:Ye, M, Shima, F, Muraoka, S, Liao, J, Okamoto, H, Yamamoto, M, Tamura, A, Yagi, N, Ueki, T, Kataoka, T.
Deposit date:2005-04-12
Release date:2005-07-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal Structure of M-Ras Reveals a GTP-bound "Off" State Conformation of Ras Family Small GTPases
J.Biol.Chem., 280, 2005
1X1S
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Crystal structure of M-Ras in complex with GppNHp
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein M-Ras
Authors:Ye, M, Shima, F, Muraoka, S, Liao, J, Okamoto, H, Yamamoto, M, Tamura, A, Yagi, N, Ueki, T, Kataoka, T.
Deposit date:2005-04-13
Release date:2005-07-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of M-Ras Reveals a GTP-bound "Off" State Conformation of Ras Family Small GTPases
J.Biol.Chem., 280, 2005
1X3S
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Crystal structure of human Rab18 in complex with Gppnhp
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Rab-18
Authors:Kukimoto-Niino, M, Murayama, K, Chen, L, Liu, Z.J, Wang, B.C, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-10
Release date:2005-11-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Crystal structure of human Rab18 in complex with Gppnhp
To be Published
1X86
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Crystal Structure of the DH/PH domains of Leukemia-associated RhoGEF in complex with RhoA
Descriptor: PHOSPHATE ION, Rho guanine nucleotide exchange factor 12, Transforming protein RhoA
Authors:Kristelly, R, Gao, G, Tesmer, J.J.
Deposit date:2004-08-17
Release date:2004-09-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.22 Å)
Cite:Structural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factor.
J.Biol.Chem., 279, 2004

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