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2GYW
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Crystal Structure of Mus musculus Acetylcholinesterase in Complex with Obidoxime
Descriptor: 1,1'-(OXYDIMETHYLENE)BIS(4-FORMYLPYRIDINIUM)DIOXIME, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, ...
Authors:Pang, Y.P, Boman, M, Artursson, E, Akfur, C, Lundberg, S.
Deposit date:2006-05-10
Release date:2006-08-15
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of acetylcholinesterase in complex with HI-6, Ortho-7 and obidoxime: Structural basis for differences in the ability to reactivate tabun conjugates.
Biochem.Pharm., 72, 2006
2YIN
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STRUCTURE OF THE COMPLEX BETWEEN Dock2 AND Rac1.
Descriptor: DEDICATOR OF CYTOKINESIS PROTEIN 2, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1
Authors:Kulkarni, K.A, Yang, J, Zhang, Z, Barford, D.
Deposit date:2011-05-16
Release date:2011-05-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Multiple Factors Confer Specific Cdc42 and Rac Protein Activation by Dedicator of Cytokinesis (Dock) Nucleotide Exchange Factors.
J.Biol.Chem., 286, 2011
2HD0
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Structure of the catalytic domain of hepatitis C virus NS2
Descriptor: DECYL-BETA-D-MALTOPYRANOSIDE, Protease NS2-3 (p23), octyl beta-D-glucopyranoside
Authors:Lorenz, I.C, Rice, C.M, Marcotrigiano, J.
Deposit date:2006-06-19
Release date:2006-08-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structure of the catalytic domain of the hepatitis C virus NS2-3 protease.
Nature, 442, 2006
2H6H
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Y365F Protein Farnesyltransferase Mutant Complexed with a Farnesylated DDPTASACVLS Peptide Product at 1.8A
Descriptor: ACETIC ACID, FARNESYL, Protein farnesyltransferase beta subunit, ...
Authors:Terry, K.L, Beese, L.S.
Deposit date:2006-05-31
Release date:2006-08-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Conversion of protein farnesyltransferase to a geranylgeranyltransferase.
Biochemistry, 45, 2006
2H7V
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Co-crystal structure of YpkA-Rac1
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Migration-inducing protein 5, ...
Authors:Prehna, G, Ivanov, M, Bliska, J.B, Stebbins, C.E.
Deposit date:2006-06-04
Release date:2006-09-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Yersinia virulence depends on mimicry of host rho-family nucleotide dissociation inhibitors.
Cell(Cambridge,Mass.), 126, 2006
2H9Y
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Crystal structure of mouse acetylcholinesterase complexed with m-(N,N,N-trimethylammonio)trifluoroacetophenone
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, HEXAETHYLENE GLYCOL, ...
Authors:Bourne, Y, Radic, Z, Sulzenbacher, G, Kim, E, Taylor, P, Marchot, P.
Deposit date:2006-06-12
Release date:2006-07-18
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Substrate and product trafficking through the active center gorge of acetylcholinesterase analyzed by crystallography and equilibrium binding
J.Biol.Chem., 281, 2006
2WJX
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Crystal structure of the human ionotropic glutamate receptor GluR2 ATD region at 4.1 A resolution
Descriptor: GLUTAMATE RECEPTOR 2
Authors:Clayton, A, Siebold, C, Gilbert, R.J.C, Sutton, G.C, Harlos, K, McIlhinney, R.A.J, Jones, E.Y, Aricescu, A.R.
Deposit date:2009-06-01
Release date:2009-08-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Crystal Structure of the Glur2 Amino-Terminal Domain Provides Insights Into the Architecture and Assembly of Ionotropic Glutamate Receptors.
J.Mol.Biol., 392, 2009
2HPY
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BU of 2hpy by Molmil
Crystallographic model of lumirhodopsin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HEPTANE-1,2,3-TRIOL, MERCURY (II) ION, ...
Authors:Nakamichi, H, Okada, T.
Deposit date:2006-07-18
Release date:2006-08-22
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Local peptide movement in the photoreaction intermediate of rhodopsin
Proc.Natl.Acad.Sci.Usa, 103, 2006
2WJV
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Crystal structure of the complex between human nonsense mediated decay factors UPF1 and UPF2
Descriptor: REGULATOR OF NONSENSE TRANSCRIPTS 1, REGULATOR OF NONSENSE TRANSCRIPTS 2, SULFATE ION, ...
Authors:Clerici, M, Mourao, A, Gutsche, I, Gehring, N.H, Hentze, M.W, Kulozik, A, Kadlec, J, Sattler, M, Cusack, S.
Deposit date:2009-06-01
Release date:2009-07-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Unusual Bipartite Mode of Interaction between the Nonsense-Mediated Decay Factors, Upf1 and Upf2.
Embo J., 28, 2009
2F88
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Solution NMR structure of domain 5 from the Pyaiella littoralis (PL) group II intron
Descriptor: D5-PL RNA RIBOZYME DOMAIN
Authors:Dayie, K.T.
Deposit date:2005-12-02
Release date:2006-02-28
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure of a self-splicing group II intron catalytic effector domain 5: parallels with spliceosomal U6 RNA
Rna, 12, 2006
2Z7G
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Crystal structure of adenosine deaminase ligated with EHNA
Descriptor: (2S,3R)-3-(6-amino-9H-purin-9-yl)nonan-2-ol, Adenosine deaminase, ZINC ION
Authors:Kinoshita, T.
Deposit date:2007-08-20
Release date:2008-07-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Conformational change of adenosine deaminase during ligand-exchange in a crystal
Biochem.Biophys.Res.Commun., 373, 2008
2F0Y
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Crystal Structure Of Human Protein Farnesyltransferase Complexed With Farnesyl Diphosphate and hydantoin derivative
Descriptor: 3-({3-[3-(1H-IMIDAZOL-1-YL)PROPYL]-5-METHYL-5-(1-NAPHTHYL)-2,4-DIOXOIMIDAZOLIDIN-1-YL}METHYL)BENZONITRILE, FARNESYL DIPHOSPHATE, Protein farnesyltransferase beta subunit, ...
Authors:Kim, K.H, Lee, J, Kim, J.
Deposit date:2005-11-14
Release date:2006-11-14
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:hydantoin derivatives as Non-pepridic inhibitors of Ras Farnesyl transferase
To be published
2FOW
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BU of 2fow by Molmil
THE RNA BINDING DOMAIN OF RIBOSOMAL PROTEIN L11: THREE-DIMENSIONAL STRUCTURE OF THE RNA-BOUND FORM OF THE PROTEIN, NMR, 26 STRUCTURES
Descriptor: RIBOSOMAL PROTEIN L11
Authors:Hinck, A.P, Markus, M.A, Huang, S, Grzesiek, S, Kustanovich, I, Draper, D.E, Torchia, D.A.
Deposit date:1997-05-26
Release date:1997-11-26
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:The RNA binding domain of ribosomal protein L11: three-dimensional structure of the RNA-bound form of the protein and its interaction with 23 S rRNA.
J.Mol.Biol., 274, 1997
2GVL
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BU of 2gvl by Molmil
Crystal Structure of Murine NMPRTase
Descriptor: Nicotinamide phosphoribosyltransferase
Authors:Khan, J.A, Tao, X, Tong, L.
Deposit date:2006-05-02
Release date:2006-07-25
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents.
Nat.Struct.Mol.Biol., 13, 2006
2GRB
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BU of 2grb by Molmil
Crystal Structure of an RNA Quadruplex Containing Inosine-tetrad
Descriptor: 5'-R(*(U33)P*GP*IP*GP*GP*U)-3', POTASSIUM ION, STRONTIUM ION
Authors:Pan, B, Shi, K, Sundaralingam, M.
Deposit date:2006-04-24
Release date:2006-11-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of an RNA quadruplex containing inosine tetrad: implications for the roles of NH2 group in purine tetrads.
J.Mol.Biol., 363, 2006
2X19
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Crystal structure of Importin13 - RanGTP complex
Descriptor: GTP-BINDING NUCLEAR PROTEIN GSP1/CNR1, GUANOSINE-5'-TRIPHOSPHATE, IMPORTIN-13, ...
Authors:Bono, F, Cook, A.G, Gruenwald, M, Ebert, J, Conti, E.
Deposit date:2009-12-23
Release date:2010-02-16
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Nuclear Import Mechanism of the Ejc Component Mago- Y14 Revealed by Structural Studies of Importin 13.
Mol.Cell, 37, 2010
2WY1
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Crystal structure of rat angiotensinogen in P321 space group
Descriptor: ANGIOTENSINOGEN
Authors:Zhou, A, Wei, Z, Carrell, R.W, Read, R.J.
Deposit date:2009-11-11
Release date:2010-10-20
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:A Redox Switch in Angiotensinogen Modulates Angiotensin Release.
Nature, 468, 2010
2WXW
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BU of 2wxw by Molmil
Crystal structure of human angiotensinogen
Descriptor: ANGIOTENSINOGEN
Authors:Zhou, A, Wei, Z, Carrell, R.W, Read, R.J.
Deposit date:2009-11-11
Release date:2010-10-20
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:A Redox Switch in Angiotensinogen Modulates Angiotensin Release.
Nature, 468, 2010
2WXZ
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BU of 2wxz by Molmil
Crystal structure of rat angiotensinogen in C2 space group
Descriptor: ANGIOTENSINOGEN
Authors:Zhou, A, Wei, Z, Carrell, R.W, Read, R.J.
Deposit date:2009-11-11
Release date:2010-10-20
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A Redox Switch in Angiotensinogen Modulates Angiotensin Release.
Nature, 468, 2010
2HYU
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BU of 2hyu by Molmil
Human Annexin A2 with heparin tetrasaccharide bound
Descriptor: 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, Annexin A2, CALCIUM ION
Authors:Shao, C, Head, J.F, Seaton, B.A.
Deposit date:2006-08-07
Release date:2006-09-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Crystallographic Analysis of Calcium-dependent Heparin Binding to Annexin A2.
J.Biol.Chem., 281, 2006
2ZNT
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Crystal structure of the ligand-binding core of the human ionotropic glutamate receptor, GluR5, in complex with a novel selective agonist, dysiherbaine
Descriptor: (2R,3aR,6S,7R,7aR)-2-[(2S)-2-amino-2-carboxyethyl]-6-hydroxy-7-(methylamino)hexahydro-2H-furo[3,2-b]pyran-2-carboxylic acid, BETA-MERCAPTOETHANOL, Glutamate receptor, ...
Authors:Unno, M, Sasaki, M, Ikeda-Saito, M.
Deposit date:2008-05-01
Release date:2009-05-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Binding and Selectivity of the Marine Toxin Neodysiherbaine A and Its Synthetic Analogues to GluK1 and GluK2 Kainate Receptors.
J.Mol.Biol., 413, 2011
2ZNU
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Crystal structure of the ligand-binding core of the human ionotropic glutamate receptor, GluR5, in complex with a novel selective agonist, neodysiherbaine A
Descriptor: (2R,3aR,6R,7R,7aR)-2-[(2S)-2-amino-2-carboxyethyl]-6,7-dihydroxyhexahydro-2H-furo[3,2-b]pyran-2-carboxylic acid, BETA-MERCAPTOETHANOL, Glutamate receptor, ...
Authors:Unno, M, Sasaki, M, Ikeda-Saito, M.
Deposit date:2008-05-01
Release date:2009-05-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Binding and Selectivity of the Marine Toxin Neodysiherbaine A and Its Synthetic Analogues to GluK1 and GluK2 Kainate Receptors.
J.Mol.Biol., 413, 2011
2I3Z
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rat DPP-IV with xanthine mimetic inhibitor #7
Descriptor: 2-[(3S)-3-AMINOPIPERIDIN-1-YL]-1-(2-CYANOBENZYL)-5-METHYL-4,6-DIOXO-3,4,5,6-TETRAHYDROPYRROLO[3,4-D]IMIDAZOL-1-IUM, Dipeptidyl peptidase 4 (Dipeptidyl peptidase IV) (DPP IV)
Authors:Kurukulasuriya, R, Rohde, J.J, Szczepankiewicz, B.G, Basha, F, Lai, C, Winn, M, Stewart, K.D, Longenecker, K.L, Lubben, T.W, Ballaron, S.J, Sham, H.L, VonGeldern, T.W.
Deposit date:2006-08-21
Release date:2006-12-12
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Xanthine mimetics as potent dipeptidyl peptidase IV inhibitors.
Bioorg.Med.Chem.Lett., 16, 2006
2HYW
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Human Annexin A2 with Calcium bound
Descriptor: Annexin A2, CALCIUM ION
Authors:Shao, C, Head, J.F, Seaton, B.A.
Deposit date:2006-08-07
Release date:2006-09-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystallographic Analysis of Calcium-dependent Heparin Binding to Annexin A2.
J.Biol.Chem., 281, 2006
2I35
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Crystal structure of rhombohedral crystal form of ground-state rhodopsin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PALMITIC ACID, RETINAL, ...
Authors:Stenkamp, R.E, Le Trong, I, Lodowski, D.T, Salom, D, Palczewski, K.
Deposit date:2006-08-17
Release date:2006-10-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Crystal structure of a photoactivated deprotonated intermediate of rhodopsin.
Proc.Natl.Acad.Sci.Usa, 103, 2006

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