6E6P
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![BU of 6e6p by Molmil](/molmil-images/mine/6e6p) | HRAS G13D bound to GppNHp (Ha,b,c13GNP) | Descriptor: | CALCIUM ION, GLYCEROL, GTPase HRas, ... | Authors: | Johnson, C.W, Mattos, C. | Deposit date: | 2018-07-25 | Release date: | 2019-07-31 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D. Cell Rep, 28, 2019
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3NCJ
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![BU of 3ncj by Molmil](/molmil-images/mine/3ncj) | Crystal structure of Fab15 Mut8 | Descriptor: | ACETATE ION, Fab15 Mut8 heavy chain, Fab15 Mut8 light chain, ... | Authors: | Luo, J, Feng, Y, Gilliland, G.L. | Deposit date: | 2010-06-04 | Release date: | 2010-08-18 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Co-evolution of antibody stability and Vk CDR-L3 canonical structure To be Published
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1CFS
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![BU of 1cfs by Molmil](/molmil-images/mine/1cfs) | ANTI-P24 (HIV-1) FAB FRAGMENT CB41 COMPLEXED WITH AN EPITOPE-UNRELATED PEPTIDE | Descriptor: | PROTEIN (ANTIGEN BOUND PEPTIDE), PROTEIN (IGG2A KAPPA ANTIBODY CB41 (HEAVY CHAIN)), PROTEIN (IGG2A KAPPA ANTIBODY CB41 (LIGHT CHAIN)) | Authors: | Keitel, T, Kramer, A, Wessner, H, Scholz, C, Schneider-Mergener, J, Hoehne, W. | Deposit date: | 1999-03-19 | Release date: | 1999-03-31 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Crystallographic analysis of anti-p24 (HIV-1) monoclonal antibody cross-reactivity and polyspecificity. Cell(Cambridge,Mass.), 91, 1997
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1CHH
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![BU of 1chh by Molmil](/molmil-images/mine/1chh) | |
6ER4
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![BU of 6er4 by Molmil](/molmil-images/mine/6er4) | Ruminococcus gnavus IT-sialidase CBM40 bound to alpha2,6 sialyllactose | Descriptor: | BNR/Asp-box repeat protein, GLYCEROL, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ... | Authors: | Owen, C.D, Tailford, L.E, Taylor, G.L, Juge, N. | Deposit date: | 2017-10-16 | Release date: | 2018-05-02 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Unravelling the specificity and mechanism of sialic acid recognition by the gut symbiont Ruminococcus gnavus. Nat Commun, 8, 2017
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1CSJ
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![BU of 1csj by Molmil](/molmil-images/mine/1csj) | CRYSTAL STRUCTURE OF THE RNA-DEPENDENT RNA POLYMERASE OF HEPATITIS C VIRUS | Descriptor: | HEPATITIS C VIRUS RNA POLYMERASE (NS5B) | Authors: | Bressanelli, S, Tomei, L, Roussel, A, Incitti, I, Vitale, R.L, Mathieu, M, De Francesco, R, Rey, F.A. | Deposit date: | 1999-08-18 | Release date: | 1999-11-08 | Last modified: | 2013-02-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus. Proc.Natl.Acad.Sci.USA, 96, 1999
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1CZD
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![BU of 1czd by Molmil](/molmil-images/mine/1czd) | CRYSTAL STRUCTURE OF THE PROCESSIVITY CLAMP GP45 FROM BACTERIOPHAGE T4 | Descriptor: | DNA POLYMERASE ACCESSORY PROTEIN G45 | Authors: | Moarefi, I, Jeruzalmi, D, Turner, J, O'Donnell, M, Kuriyan, J. | Deposit date: | 1999-09-02 | Release date: | 2000-03-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Crystal structure of the DNA polymerase processivity factor of T4 bacteriophage. J.Mol.Biol., 296, 2000
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1D7K
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![BU of 1d7k by Molmil](/molmil-images/mine/1d7k) | CRYSTAL STRUCTURE OF HUMAN ORNITHINE DECARBOXYLASE AT 2.1 ANGSTROMS RESOLUTION | Descriptor: | HUMAN ORNITHINE DECARBOXYLASE | Authors: | Almrud, J.J, Oliveira, M.A, Kern, A.D, Grishin, N.V, Phillips, M.A, Hackert, M.L. | Deposit date: | 1999-10-18 | Release date: | 2000-10-25 | Last modified: | 2018-01-31 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of human ornithine decarboxylase at 2.1 A resolution: structural insights to antizyme binding. J.Mol.Biol., 295, 2000
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1CZG
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![BU of 1czg by Molmil](/molmil-images/mine/1czg) | |
1CZW
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![BU of 1czw by Molmil](/molmil-images/mine/1czw) | |
3NHZ
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![BU of 3nhz by Molmil](/molmil-images/mine/3nhz) | Structure of N-terminal Domain of MtrA | Descriptor: | MAGNESIUM ION, Two component system transcriptional regulator mtrA | Authors: | Barbieri, C.M, Mack, T.R, Robinson, V.L, Miller, M.T, Stock, A.M. | Deposit date: | 2010-06-14 | Release date: | 2010-08-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Regulation of response regulator autophosphorylation through interdomain contacts. J.Biol.Chem., 285, 2010
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1CO7
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![BU of 1co7 by Molmil](/molmil-images/mine/1co7) | |
1D0I
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![BU of 1d0i by Molmil](/molmil-images/mine/1d0i) | CRYSTAL STRUCTURE OF TYPE II DEHYDROQUINASE FROM STREPTOMYCES COELICOLOR COMPLEXED WITH PHOSPHATE IONS | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PHOSPHATE ION, TYPE II 3-DEHYDROQUINATE HYDRATASE | Authors: | Roszak, A.W, Krell, T, Hunter, I.S, Coggins, J.R, Lapthorn, A.J. | Deposit date: | 1999-09-10 | Release date: | 2000-09-13 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The structure and mechanism of the type II dehydroquinase from Streptomyces coelicolor. Structure, 10, 2002
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1D2Z
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![BU of 1d2z by Molmil](/molmil-images/mine/1d2z) | THREE-DIMENSIONAL STRUCTURE OF A COMPLEX BETWEEN THE DEATH DOMAINS OF PELLE AND TUBE | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DEATH DOMAIN OF PELLE, DEATH DOMAIN OF TUBE | Authors: | Xiao, T, Towb, P, Wasserman, S.A, Sprang, S.R. | Deposit date: | 1999-09-28 | Release date: | 1999-11-29 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Three-dimensional structure of a complex between the death domains of Pelle and Tube. Cell(Cambridge,Mass.), 99, 1999
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1D3A
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![BU of 1d3a by Molmil](/molmil-images/mine/1d3a) | CRYSTAL STRUCTURE OF THE WILD TYPE HALOPHILIC MALATE DEHYDROGENASE IN THE APO FORM | Descriptor: | CHLORIDE ION, HALOPHILIC MALATE DEHYDROGENASE, SODIUM ION | Authors: | Richard, S.B, Madern, D, Garcin, E, Zaccai, G. | Deposit date: | 1999-09-28 | Release date: | 2000-03-20 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.94 Å) | Cite: | Halophilic adaptation: novel solvent protein interactions observed in the 2.9 and 2.6 A resolution structures of the wild type and a mutant of malate dehydrogenase from Haloarcula marismortui. Biochemistry, 39, 2000
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1CFN
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![BU of 1cfn by Molmil](/molmil-images/mine/1cfn) | ANTI-P24 (HIV-1) FAB FRAGMENT CB41 COMPLEXED WITH AN EPITOPE-RELATED PEPTIDE | Descriptor: | PROTEIN (BOUND PEPTIDE), PROTEIN (IGG2A KAPPA ANTIBODY CB41 (LIGHT CHAIN)), PROTEIN (IGG2A-KAPPA ANTIBODY CB41 (HEAVY CHAIN)) | Authors: | Keitel, T, Kramer, A, Wessner, H, Scholz, C, Schneider-Mergener, J, Hoehne, W. | Deposit date: | 1999-03-19 | Release date: | 1999-03-30 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Crystallographic analysis of anti-p24 (HIV-1) monoclonal antibody cross-reactivity and polyspecificity. Cell(Cambridge,Mass.), 91, 1997
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6FM3
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![BU of 6fm3 by Molmil](/molmil-images/mine/6fm3) | Deoxyguanylosuccinate synthase (DgsS) structure with ADP at 1.9 Angstrom resolution | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Adenylosuccinate synthetase, CHLORIDE ION | Authors: | Sleiman, D, Loc'h, J, Haouz, A, Kaminski, P.A. | Deposit date: | 2018-01-30 | Release date: | 2019-06-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Deoxyguanylosuccinate synthase (DgsS) quaternary structure with ATP0, dGMP, Magnesium at 2.3 Angstrom resolution To Be Published
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2PQJ
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![BU of 2pqj by Molmil](/molmil-images/mine/2pqj) | Crystal structure of active ribosome inactivating protein from maize (b-32), complex with adenine | Descriptor: | ADENINE, Ribosome-inactivating protein 3 | Authors: | Mak, A.N.S, Au, S.W.N, Cha, S.S, Young, J.A, Wong, K.B, Shaw, P.C. | Deposit date: | 2007-05-02 | Release date: | 2008-02-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure-function study of maize ribosome-inactivating protein: implications for the internal inactivation region and the sole glutamate in the active site. Nucleic Acids Res., 35, 2007
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3P8E
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![BU of 3p8e by Molmil](/molmil-images/mine/3p8e) | Crystal structure of human DIMETHYLARGININE DIMETHYLAMINOHYDROLASE-1 (DDAH-1) covalently bound with N5-(1-iminopentyl)-L-ornithine | Descriptor: | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1, N~5~-[(1S)-1-aminopentyl]-L-ornithine | Authors: | Lluis, M, Wang, Y, Monzingo, A.F, Fast, W, Robertus, J.D. | Deposit date: | 2010-10-13 | Release date: | 2010-11-10 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4946 Å) | Cite: | Characterization of C-Alkyl Amidines as Bioavailable Covalent Reversible Inhibitors of Human DDAH-1. Chemmedchem, 6, 2011
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3FRV
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![BU of 3frv by Molmil](/molmil-images/mine/3frv) | |
6H29
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![BU of 6h29 by Molmil](/molmil-images/mine/6h29) | HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH BENZYL CARBAMATE | Descriptor: | (phenylmethyl) carbamate, Carbonic anhydrase 2, ZINC ION | Authors: | Alterio, V, De Simone, G. | Deposit date: | 2018-07-13 | Release date: | 2018-09-05 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Inhibition of carbonic anhydrases by a substrate analog: benzyl carbamate directly coordinates the catalytic zinc ion mimicking bicarbonate binding. Chem. Commun. (Camb.), 54, 2018
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6H2S
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![BU of 6h2s by Molmil](/molmil-images/mine/6h2s) | |
2PQI
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![BU of 2pqi by Molmil](/molmil-images/mine/2pqi) | Crystal structure of active ribosome inactivating protein from maize (b-32) | Descriptor: | Ribosome-inactivating protein 3 | Authors: | Mak, A.N.S, Wong, Y.T, Young, J.A, Cha, S.S, Sze, K.H, Au, S.W.N, Wong, K.B, Shaw, P.C. | Deposit date: | 2007-05-02 | Release date: | 2008-02-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure-function study of maize ribosome-inactivating protein: implications for the internal inactivation region and the sole glutamate in the active site. Nucleic Acids Res., 35, 2007
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3GDX
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![BU of 3gdx by Molmil](/molmil-images/mine/3gdx) | Dna polymerase beta with a gapped DND substrate and dTMP(CF2)PP | Descriptor: | 5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... | Authors: | Wilson, S.H, Batra, V.K, Pedersen, L.C. | Deposit date: | 2009-02-24 | Release date: | 2009-05-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Alpha,beta-difluoromethylene deoxynucleoside 5'-triphosphates: a convenient synthesis of useful probes for DNA polymerase beta structure and function Org.Lett., 11, 2009
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6GHP
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![BU of 6ghp by Molmil](/molmil-images/mine/6ghp) | 14-3-3sigma in complex with a TASK3 peptide stabilized by semi-synthetic natural product FC-NAc | Descriptor: | 14-3-3 protein sigma, CHLORIDE ION, Potassium channel subfamily K member 9, ... | Authors: | Andrei, S.A, de Vink, P.J, Brunsveld, L, Ottmann, C, Higuchi, Y. | Deposit date: | 2018-05-08 | Release date: | 2018-08-01 | Last modified: | 2018-10-17 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Rationally Designed Semisynthetic Natural Product Analogues for Stabilization of 14-3-3 Protein-Protein Interactions. Angew. Chem. Int. Ed. Engl., 57, 2018
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