6H29
HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH BENZYL CARBAMATE
Summary for 6H29
Entry DOI | 10.2210/pdb6h29/pdb |
Descriptor | Carbonic anhydrase 2, ZINC ION, (phenylmethyl) carbamate, ... (4 entities in total) |
Functional Keywords | benzyl carbamate, inhibitor complex, human carbonic anhydrase ii, lyase |
Biological source | Homo sapiens |
Total number of polymer chains | 1 |
Total formula weight | 29505.63 |
Authors | Alterio, V.,De Simone, G. (deposition date: 2018-07-13, release date: 2018-09-05, Last modification date: 2024-01-17) |
Primary citation | De Simone, G.,Angeli, A.,Bozdag, M.,Supuran, C.T.,Winum, J.Y.,Monti, S.M.,Alterio, V. Inhibition of carbonic anhydrases by a substrate analog: benzyl carbamate directly coordinates the catalytic zinc ion mimicking bicarbonate binding. Chem. Commun. (Camb.), 54:10312-10315, 2018 Cited by PubMed: 30140816DOI: 10.1039/c8cc05755a PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.46 Å) |
Structure validation
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