6ROL
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![BU of 6rol by Molmil](/molmil-images/mine/6rol) | Structure of IMP2 KH34 domains | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Insulin-like growth factor 2 mRNA-binding protein 2, ... | Authors: | Bhaskar, V, Biswas, J, Singer, R.H, Chao, J.A. | Deposit date: | 2019-05-13 | Release date: | 2019-10-16 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The structural basis for RNA selectivity by the IMP family of RNA-binding proteins. Nat Commun, 10, 2019
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7KWG
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![BU of 7kwg by Molmil](/molmil-images/mine/7kwg) | Staphylococcus aureus 30S ribosomal subunit in presence of spermidine | Descriptor: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Belinite, M, Khusainov, I, Marzi, S, Romby, P, Yusupov, M, Hashem, Y. | Deposit date: | 2020-11-30 | Release date: | 2021-01-27 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.75 Å) | Cite: | Stabilization of Ribosomal RNA of the Small Subunit by Spermidine in Staphylococcus aureus . Front Mol Biosci, 8, 2021
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8JSM
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![BU of 8jsm by Molmil](/molmil-images/mine/8jsm) | The structure of EBOV L-VP35-RNA complex (conformation 1) | Descriptor: | Polymerase cofactor VP35, RNA-directed RNA polymerase L, The leader sequence of EBOV genome., ... | Authors: | Qi, P, Yi, S. | Deposit date: | 2023-06-20 | Release date: | 2023-09-27 | Last modified: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Molecular mechanism of de novo replication by the Ebola virus polymerase. Nature, 622, 2023
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8JSL
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![BU of 8jsl by Molmil](/molmil-images/mine/8jsl) | The structure of EBOV L-VP35-RNA complex | Descriptor: | Polymerase cofactor VP35, RNA-directed RNA polymerase L, The leader sequence of EBOV, ... | Authors: | Qi, P, Yi, S. | Deposit date: | 2023-06-20 | Release date: | 2023-09-27 | Last modified: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (2.95 Å) | Cite: | Molecular mechanism of de novo replication by the Ebola virus polymerase. Nature, 622, 2023
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8JSN
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![BU of 8jsn by Molmil](/molmil-images/mine/8jsn) | The structure of EBOV L-VP35-RNA complex (conformation 2) | Descriptor: | Polymerase cofactor VP35, RNA-directed RNA polymerase L, The leader sequence of EBOV genome, ... | Authors: | Qi, P, Yi, S. | Deposit date: | 2023-06-20 | Release date: | 2023-09-27 | Last modified: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Molecular mechanism of de novo replication by the Ebola virus polymerase. Nature, 622, 2023
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8WI9
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![BU of 8wi9 by Molmil](/molmil-images/mine/8wi9) | Cryo- EM structure of Mycobacterium smegmatis 30S ribosomal subunit (body 2) of 70S ribosome, bS1 and RafH. | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Kumar, N, Sharma, S, Kaushal, P.S. | Deposit date: | 2023-09-24 | Release date: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH. Nat Commun, 15, 2024
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8WIF
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![BU of 8wif by Molmil](/molmil-images/mine/8wif) | Cryo- EM structure of Mycobacterium smegmatis 30S ribosomal subunit (body 2) of 70S ribosome and RafH. | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Kumar, N, Sharma, S, Kaushal, P.S. | Deposit date: | 2023-09-24 | Release date: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH. Nat Commun, 15, 2024
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7AQD
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![BU of 7aqd by Molmil](/molmil-images/mine/7aqd) | |
7AQC
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![BU of 7aqc by Molmil](/molmil-images/mine/7aqc) | Structure of the bacterial RQC complex (Decoding State) | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L11, 50S ribosomal protein L13, ... | Authors: | Filbeck, S, Pfeffer, S. | Deposit date: | 2020-10-21 | Release date: | 2020-11-25 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.99 Å) | Cite: | Mimicry of Canonical Translation Elongation Underlies Alanine Tail Synthesis in RQC. Mol.Cell, 81, 2021
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7P7S
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![BU of 7p7s by Molmil](/molmil-images/mine/7p7s) | PoxtA-EQ2 antibiotic resistance ABCF bound to E. faecalis 70S ribosome, state II | Descriptor: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | Authors: | Crowe-McAuliffe, C, Wilson, D.N. | Deposit date: | 2021-07-20 | Release date: | 2022-02-23 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics. Nat Commun, 13, 2022
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7P7R
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![BU of 7p7r by Molmil](/molmil-images/mine/7p7r) | PoxtA-EQ2 antibiotic resistance ABCF bound to E. faecalis 70S ribosome, state I | Descriptor: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | Authors: | Crowe-McAuliffe, C, Wilson, D.N. | Deposit date: | 2021-07-20 | Release date: | 2022-03-23 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics. Nat Commun, 13, 2022
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4ADV
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![BU of 4adv by Molmil](/molmil-images/mine/4adv) | Structure of the E. coli methyltransferase KsgA bound to the E. coli 30S ribosomal subunit | Descriptor: | 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | Authors: | Boehringer, D, O'Farrell, H.C, Rife, J.P, Ban, N. | Deposit date: | 2012-01-03 | Release date: | 2012-02-15 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (13.5 Å) | Cite: | Structural Insights Into Methyltransferase Ksga Function in 30S Ribosomal Subunit Biogenesis J.Biol.Chem., 287, 2012
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8HUJ
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![BU of 8huj by Molmil](/molmil-images/mine/8huj) | Cryo-EM structure of the J-K-St region of EMCV IRES in complex with eIF4G-HEAT1 and eIF4A | Descriptor: | Eukaryotic initiation factor 4A-I, Eukaryotic translation initiation factor 4 gamma 1, IRES RNA (J-K-St), ... | Authors: | Suzuki, H, Fujiyoshi, Y, Imai, S, Shimada, I. | Deposit date: | 2022-12-24 | Release date: | 2023-08-02 | Last modified: | 2023-09-13 | Method: | ELECTRON MICROSCOPY (3.76 Å) | Cite: | Dynamically regulated two-site interaction of viral RNA to capture host translation initiation factor. Nat Commun, 14, 2023
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5W4K
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![BU of 5w4k by Molmil](/molmil-images/mine/5w4k) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with Klebsazolicin and bound to mRNA and A-, P- and E-site tRNAs at 2.7A resolution | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Metelev, M, Osterman, I.A, Ghilarov, D, Khabibullina, N.F, Yakimov, A, Shabalin, K, Utkina, I, Travin, D.Y, Komarova, E.S, Serebryakova, M, Artamonova, T, Khodorkovskii, M, Konevega, A.L, Sergiev, P.V, Severinov, K, Polikanov, Y.S. | Deposit date: | 2017-06-12 | Release date: | 2017-08-30 | Last modified: | 2019-12-04 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Klebsazolicin inhibits 70S ribosome by obstructing the peptide exit tunnel. Nat. Chem. Biol., 13, 2017
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8FR8
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![BU of 8fr8 by Molmil](/molmil-images/mine/8fr8) | Structure of Mycobacterium smegmatis Rsh bound to a 70S translation initiation complex | Descriptor: | 16S rRNA (1511-MER), 23S rRNA (3119-MER), 30S ribosomal protein S10, ... | Authors: | Majumdar, S, Sharma, M.R, Manjari, S.R, Banavali, N.K, Agrawal, R.K. | Deposit date: | 2023-01-06 | Release date: | 2023-05-17 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | Starvation sensing by mycobacterial RelA/SpoT homologue through constitutive surveillance of translation. Proc.Natl.Acad.Sci.USA, 120, 2023
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5AFF
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![BU of 5aff by Molmil](/molmil-images/mine/5aff) | Symportin 1 chaperones 5S RNP assembly during ribosome biogenesis by occupying an essential rRNA binding site | Descriptor: | RIBOSOMAL PROTEIN L11, RIBOSOMAL PROTEIN L5, SYMPORTIN 1 | Authors: | Calvino, F.R, Kharde, S, Wild, K, Bange, G, Sinning, I. | Deposit date: | 2015-01-21 | Release date: | 2015-04-15 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.398 Å) | Cite: | Symportin 1 Chaperones 5S Rnp Assembly During Ribosome Biogenesis by Occupying an Essential Rrna-Binding Site. Nat.Commun., 6, 2015
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1HUS
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![BU of 1hus by Molmil](/molmil-images/mine/1hus) | RIBOSOMAL PROTEIN S7 | Descriptor: | RIBOSOMAL PROTEIN S7 | Authors: | Hosaka, H, Nakagawa, A, Tanaka, I. | Deposit date: | 1997-08-08 | Release date: | 1998-01-28 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Ribosomal protein S7: a new RNA-binding motif with structural similarities to a DNA architectural factor. Structure, 5, 1997
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1M90
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![BU of 1m90 by Molmil](/molmil-images/mine/1m90) | Co-crystal structure of CCA-Phe-caproic acid-biotin and sparsomycin bound to the 50S ribosomal subunit | Descriptor: | 23S RRNA, 5S RRNA, 6-AMINOHEXANOIC ACID, ... | Authors: | Hansen, J.L, Schmeing, T.M, Moore, P.B, Steitz, T.A. | Deposit date: | 2002-07-26 | Release date: | 2002-09-06 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural insights into peptide bond formation. Proc.Natl.Acad.Sci.USA, 99, 2002
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1FEQ
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![BU of 1feq by Molmil](/molmil-images/mine/1feq) | NMR SOLUTION STRUCTURE OF THE ANTICODON OF TRNA(LYS3) WITH T6A MODIFICATION AT POSITION 37 | Descriptor: | 5'-R(*GP*CP*AP*GP*AP*CP*UP*UP*UP*UP*(T6A)P*AP*UP*CP*UP*GP*C)-3' | Authors: | Stuart, J.W, Gdaniec, Z, Guenther, R.H, Marszalek, M, Sochacka, E, Malkiewicz, A, Agris, P.F. | Deposit date: | 2000-07-21 | Release date: | 2000-11-22 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Functional anticodon architecture of human tRNALys3 includes disruption of intraloop hydrogen bonding by the naturally occurring amino acid modification, t6A. Biochemistry, 39, 2000
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3JAP
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![BU of 3jap by Molmil](/molmil-images/mine/3jap) | Structure of a partial yeast 48S preinitiation complex in closed conformation | Descriptor: | 18S rRNA, MAGNESIUM ION, METHIONINE, ... | Authors: | Llacer, J.L, Hussain, T, Ramakrishnan, V. | Deposit date: | 2015-06-18 | Release date: | 2015-08-12 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (4.9 Å) | Cite: | Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex. Mol.Cell, 59, 2015
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6T0R
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![BU of 6t0r by Molmil](/molmil-images/mine/6t0r) | Bat Influenza A polymerase product dissociation complex using 44-mer vRNA template with mutated oligo(U) sequence | Descriptor: | Polymerase acidic protein, Polymerase basic protein 2, RNA-directed RNA polymerase catalytic subunit, ... | Authors: | Wandzik, J.M, Kouba, T, Cusack, S. | Deposit date: | 2019-10-03 | Release date: | 2020-04-15 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.82 Å) | Cite: | A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase. Cell, 181, 2020
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6T0U
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![BU of 6t0u by Molmil](/molmil-images/mine/6t0u) | Bat Influenza A polymerase product dissociation complex using 44-mer vRNA template with intact oligo(U) sequence | Descriptor: | Polymerase acidic protein, Polymerase basic protein 2, RNA-directed RNA polymerase catalytic subunit, ... | Authors: | Wandzik, J.M, Kouba, T, Cusack, S. | Deposit date: | 2019-10-03 | Release date: | 2020-04-15 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.12 Å) | Cite: | A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase. Cell, 181, 2020
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1KC8
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![BU of 1kc8 by Molmil](/molmil-images/mine/1kc8) | Co-crystal Structure of Blasticidin S Bound to the 50S Ribosomal Subunit | Descriptor: | 23S RRNA, 5S RRNA, BLASTICIDIN S, ... | Authors: | Hansen, J.L, Ban, N, Nissen, P, Moore, P.B, Steitz, T.A. | Deposit date: | 2001-11-07 | Release date: | 2003-07-22 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Structures of Five Antibiotics Bound at the Peptidyl Transferase Center of
the Large Ribosomal Subunit J.Mol.Biol., 330, 2003
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2R7F
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![BU of 2r7f by Molmil](/molmil-images/mine/2r7f) | Crystal structure of ribonuclease II family protein from Deinococcus radiodurans, hexagonal crystal form. NorthEast Structural Genomics target DrR63 | Descriptor: | Ribonuclease II family protein | Authors: | Seetharaman, J, Neely, H, Forouhar, F, Wang, D, Fang, Y, Cunningham, K, Ma, L.-C, Xia, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2007-09-07 | Release date: | 2007-10-02 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The Structure and Enzymatic Properties of a Novel RNase II Family Enzyme from Deinococcus radiodurans. J.Mol.Biol., 415, 2012
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3SDJ
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![BU of 3sdj by Molmil](/molmil-images/mine/3sdj) | Structure of RNase-inactive point mutant of oligomeric kinase/RNase Ire1 | Descriptor: | N~2~-1H-benzimidazol-5-yl-N~4~-(3-cyclopropyl-1H-pyrazol-5-yl)pyrimidine-2,4-diamine, Serine/threonine-protein kinase/endoribonuclease IRE1 | Authors: | Korennykh, A, Korostelev, A, Egea, P, Finer-Moore, J, Zhang, C, Stroud, R, Shokat, K, Walter, P. | Deposit date: | 2011-06-09 | Release date: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3.65 Å) | Cite: | Structural and functional basis for RNA cleavage by Ire1. Bmc Biol., 9, 2011
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