8HUJ

Cryo-EM structure of the J-K-St region of EMCV IRES in complex with eIF4G-HEAT1 and eIF4A

Summary for 8HUJ

Entry DOI	10.2210/pdb8huj/pdb
EMDB information	35041
Descriptor	Eukaryotic initiation factor 4A-I, Eukaryotic translation initiation factor 4 gamma 1, IRES RNA (J-K-St), ... (5 entities in total)
Functional Keywords	translation initiation factors, translation, rna binding protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	3
Total formula weight	115357.77
Authors	Suzuki, H.,Fujiyoshi, Y.,Imai, S.,Shimada, I. (deposition date: 2022-12-24, release date: 2023-08-02, Last modification date: 2023-09-13)
Primary citation	Imai, S.,Suzuki, H.,Fujiyoshi, Y.,Shimada, I. Dynamically regulated two-site interaction of viral RNA to capture host translation initiation factor. Nat Commun, 14:4977-4977, 2023 Cited by PubMed: 37640715 DOI: 10.1038/s41467-023-40582-6 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.76 Å)

Structure validation