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8UKU
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BU of 8uku by Molmil
RNA polymerase II elongation complex with Fapy-dG lesion with CMP added
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Hou, P, Oh, J, Wang, D.
Deposit date:2023-10-15
Release date:2024-04-24
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG.
J.Am.Chem.Soc., 146, 2024
8UKR
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BU of 8ukr by Molmil
RNA polymerase II elongation complex with Fapy-dG lesion soaking with ATP before chemistry
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Hou, P, Oh, J, Wang, D.
Deposit date:2023-10-15
Release date:2024-04-24
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.78 Å)
Cite:Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG.
J.Am.Chem.Soc., 146, 2024
8UKS
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BU of 8uks by Molmil
RNA polymerase II elongation complex with Fapy-dG lesion soaking with CTP before chemistry
Descriptor: CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Hou, P, Oh, J, Wang, D.
Deposit date:2023-10-15
Release date:2024-04-24
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG.
J.Am.Chem.Soc., 146, 2024
8UKT
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BU of 8ukt by Molmil
RNA polymerase II elongation complex with Fapy-dG lesion with AMP added
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Hou, P, Oh, J, Wang, D.
Deposit date:2023-10-15
Release date:2024-04-24
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG.
J.Am.Chem.Soc., 146, 2024
5SVA
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BU of 5sva by Molmil
Mediator-RNA Polymerase II Pre-Initiation Complex
Descriptor: 108bp HIS4 Promoter Non-template Strand (-92/+16), 108bp HIS4 Promoter Template Strand (+16/-92), DNA repair helicase RAD25, ...
Authors:Robinson, P.J, Bushnell, D.A, Kornberg, R.D.
Deposit date:2016-08-05
Release date:2016-09-28
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (15.3 Å)
Cite:Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex.
Cell, 166, 2016
8UKQ
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BU of 8ukq by Molmil
RNA polymerase II elongation complex with Fapy-dG lesion in apo state
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Hou, P, Oh, J, Wang, D.
Deposit date:2023-10-15
Release date:2024-04-24
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG.
J.Am.Chem.Soc., 146, 2024
6UPZ
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BU of 6upz by Molmil
RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 3
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Oh, J, Wang, D.
Deposit date:2019-10-18
Release date:2020-06-10
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:RNA polymerase II stalls on oxidative DNA damage via a torsion-latch mechanism involving lone pair-pi and CH-pi interactions.
Proc.Natl.Acad.Sci.USA, 117, 2020
6UPY
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BU of 6upy by Molmil
RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 2E
Descriptor: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Oh, J, Wang, D.
Deposit date:2019-10-18
Release date:2020-06-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:RNA polymerase II stalls on oxidative DNA damage via a torsion-latch mechanism involving lone pair-pi and CH-pi interactions.
Proc.Natl.Acad.Sci.USA, 117, 2020
6UQ3
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BU of 6uq3 by Molmil
RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 5
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Oh, J, Wang, D.
Deposit date:2019-10-18
Release date:2020-06-10
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (3.47 Å)
Cite:RNA polymerase II stalls on oxidative DNA damage via a torsion-latch mechanism involving lone pair-pi and CH-pi interactions.
Proc.Natl.Acad.Sci.USA, 117, 2020
6UPX
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BU of 6upx by Molmil
RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 1
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Oh, J, Wang, D.
Deposit date:2019-10-18
Release date:2020-06-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:RNA polymerase II stalls on oxidative DNA damage via a torsion-latch mechanism involving lone pair-pi and CH-pi interactions.
Proc.Natl.Acad.Sci.USA, 117, 2020
6UQ0
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BU of 6uq0 by Molmil
RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 4
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Oh, J, Wang, D.
Deposit date:2019-10-18
Release date:2020-06-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.56 Å)
Cite:RNA polymerase II stalls on oxidative DNA damage via a torsion-latch mechanism involving lone pair-pi and CH-pi interactions.
Proc.Natl.Acad.Sci.USA, 117, 2020
6UQ2
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BU of 6uq2 by Molmil
RNA polymerase II elongation complex with dG in state 1
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Oh, J, Wang, D.
Deposit date:2019-10-18
Release date:2020-06-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:RNA polymerase II stalls on oxidative DNA damage via a torsion-latch mechanism involving lone pair-pi and CH-pi interactions.
Proc.Natl.Acad.Sci.USA, 117, 2020
6UQ1
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BU of 6uq1 by Molmil
RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 6
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Oh, J, Wang, D.
Deposit date:2019-10-18
Release date:2020-06-10
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:RNA polymerase II stalls on oxidative DNA damage via a torsion-latch mechanism involving lone pair-pi and CH-pi interactions.
Proc.Natl.Acad.Sci.USA, 117, 2020
5XON
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BU of 5xon by Molmil
RNA Polymerase II elongation complex bound with Spt4/5 and TFIIS
Descriptor: DNA (48-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Ehara, H, Yokoyama, T, Shigematsu, H, Shirouzu, M, Sekine, S.
Deposit date:2017-05-29
Release date:2017-08-16
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.83 Å)
Cite:Structure of the complete elongation complex of RNA polymerase II with basal factors
Science, 357, 2017
1I3Q
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BU of 1i3q by Molmil
RNA POLYMERASE II CRYSTAL FORM I AT 3.1 A RESOLUTION
Descriptor: DNA-DIRECTED RNA POLYMERASE II 13.6KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 14.2KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 14.5KD POLYPEPTIDE, ...
Authors:Cramer, P, Bushnell, D.A, Kornberg, R.D.
Deposit date:2001-02-15
Release date:2001-04-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution.
Science, 292, 2001
1I6H
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BU of 1i6h by Molmil
RNA POLYMERASE II ELONGATION COMPLEX
Descriptor: 5'-D(P*AP*AP*AP*TP*GP*CP*CP*TP*GP*GP*TP*CP*T)-3', 5'-R(P*GP*AP*CP*CP*AP*GP*GP*CP*A)-3', DNA-DIRECTED RNA POLYMERASE II 13.6KD POLYPEPTIDE, ...
Authors:Gnatt, A.L, Cramer, P, Kornberg, R.D.
Deposit date:2001-03-02
Release date:2001-04-23
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 A resolution.
Science, 292, 2001
4A93
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BU of 4a93 by Molmil
RNA Polymerase II elongation complex containing a CPD Lesion
Descriptor: 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*T*TTP*TP*TP*CP*C BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*TP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*TP)-3', 5'-R(*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*AP*AP)-3', ...
Authors:Walmacq, C, Cheung, A.C.M, Kireeva, M.L, Lubkowska, L, Ye, C, Gotte, D, Strathern, J.N, Carell, T, Cramer, P, Kashlev, M.
Deposit date:2011-11-23
Release date:2012-03-21
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Mechanism of Translesion Transcription by RNA Polymerase II and its Role in Cellular Resistance to DNA Damage.
Mol.Cell, 46, 2012
1R9S
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BU of 1r9s by Molmil
RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX, MATCHED NUCLEOTIDE
Descriptor: DNA strand, DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 14.2 kDa polypeptide, ...
Authors:Westover, K.D, Bushnell, D.A, Kornberg, R.D.
Deposit date:2003-10-30
Release date:2004-11-16
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (4.25 Å)
Cite:Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center.
Cell(Cambridge,Mass.), 119, 2004
1R9T
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BU of 1r9t by Molmil
RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX, MISMATCHED NUCLEOTIDE
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA nontemplate strand, DNA template strand, ...
Authors:Westover, K.D, Bushnell, D.A, Kornberg, R.D.
Deposit date:2003-10-30
Release date:2004-11-16
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center.
Cell(Cambridge,Mass.), 119, 2004
1SFO
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BU of 1sfo by Molmil
RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX
Descriptor: DNA STRAND, DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 14.2 kDa polypeptide, ...
Authors:Westover, K.D, Bushnell, D.A, Kornberg, R.D.
Deposit date:2004-02-20
Release date:2004-03-02
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.61 Å)
Cite:Structural Basis of Transcription: Separation of RNA from DNA by RNA Polymerase II
Science, 303, 2004
1R5U
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BU of 1r5u by Molmil
RNA POLYMERASE II TFIIB COMPLEX
Descriptor: DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 14.2 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, ...
Authors:Bushnell, D.A, Westover, K.D, Davis, R, Kornberg, R.D.
Deposit date:2003-10-13
Release date:2004-02-17
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Structural basis of transcription: an RNA polymerase II-TFIIB cocrystal at 4.5 Angstroms.
Science, 303, 2004
3H0G
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BU of 3h0g by Molmil
RNA Polymerase II from Schizosaccharomyces pombe
Descriptor: DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Spahr, H, Calero, G, Bushnell, D.A, Kornberg, R.D.
Deposit date:2009-04-09
Release date:2009-08-25
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:Schizosacharomyces pombe RNA polymerase II at 3.6-A resolution.
Proc.Natl.Acad.Sci.USA, 106, 2009
3CQZ
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BU of 3cqz by Molmil
Crystal structure of 10 subunit RNA polymerase II in complex with the inhibitor alpha-amanitin
Descriptor: ALPHA-AMANITIN, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, ...
Authors:Kaplan, C.D, Larsson, K.-M, Kornberg, R.D.
Deposit date:2008-04-03
Release date:2008-07-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The RNA Polymerase II Trigger Loop Functions in Substrate Selection and is Directly Targeted by Alpha-Amanitin.
Mol.Cell, 30, 2008
7NVR
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BU of 7nvr by Molmil
Human Mediator with RNA Polymerase II Pre-initiation complex
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Rengachari, S, Schilbach, S, Aibara, S, Cramer, P.
Deposit date:2021-03-15
Release date:2021-05-05
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structures of mammalian RNA polymerase II pre-initiation complexes.
Nature, 594, 2021
8CEO
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BU of 8ceo by Molmil
Yeast RNA polymerase II transcription pre-initiation complex with core Mediator and the +1 nucleosome
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Wang, H, Cramer, P.
Deposit date:2023-02-02
Release date:2023-03-08
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Yeast PIC-Mediator structure with RNA polymerase II C-terminal domain.
Proc.Natl.Acad.Sci.USA, 120, 2023

238582

PDB entries from 2025-07-09

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