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8CT6
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BU of 8ct6 by Molmil
1F8 mAb in complex with the computationally optimized broadly reactive H1 influenza hemagglutinin P1
Descriptor: 1F8 heavy chain, 1F8 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Dzimianski, J.V, DuBois, R.M.
Deposit date:2022-05-13
Release date:2023-04-19
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural insights into the broad protection against H1 influenza viruses by a computationally optimized hemagglutinin vaccine.
Commun Biol, 6, 2023
7K5X
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BU of 7k5x by Molmil
Cryo-EM structure of a chromatosome containing human linker histone H1.0
Descriptor: DNA (197-MER), Histone H1.0, Histone H2A type 1-B/E, ...
Authors:Zhou, B.-R, Bai, Y.
Deposit date:2020-09-17
Release date:2020-11-25
Last modified:2021-01-20
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:Distinct Structures and Dynamics of Chromatosomes with Different Human Linker Histone Isoforms.
Mol.Cell, 81, 2021
7UYI
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BU of 7uyi by Molmil
Crystal structure of the computationally optimized broadly reactive H1 influenza hemagglutinin P1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COBRA P1 HA, ...
Authors:Dzimianski, J.V, DuBois, R.M.
Deposit date:2022-05-06
Release date:2023-04-19
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural insights into the broad protection against H1 influenza viruses by a computationally optimized hemagglutinin vaccine.
Commun Biol, 6, 2023
6G57
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BU of 6g57 by Molmil
Structure of the H1 domain of human KCTD8
Descriptor: BTB/POZ domain-containing protein KCTD8
Authors:Pinkas, D.M, Bufton, J.C, Strain-Damerell, C.M, Fairhead, M, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N.
Deposit date:2018-03-29
Release date:2019-03-20
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the H1 domain of human KCTD8
To Be Published
7K5Y
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BU of 7k5y by Molmil
Cryo-EM structure of a chromatosome containing human linker histone H1.4
Descriptor: DNA (197-MER), Histone H1.4, Histone H2A type 1-B/E, ...
Authors:Zhou, B.-R, Bai, Y.
Deposit date:2020-09-17
Release date:2020-11-25
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Distinct Structures and Dynamics of Chromatosomes with Different Human Linker Histone Isoforms.
Mol.Cell, 81, 2021
8GZ4
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BU of 8gz4 by Molmil
Crystal structure of MPXV phosphatase
Descriptor: Dual specificity protein phosphatase H1, PHOSPHATE ION
Authors:Yang, H.T, Wang, W, Huang, H.J, Ji, X.Y.
Deposit date:2022-09-25
Release date:2023-05-17
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:Crystal structure of monkeypox H1 phosphatase, an antiviral drug target.
Protein Cell, 14, 2023
7K60
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BU of 7k60 by Molmil
Cryo-EM structure of a chromatosome containing human linker histone H1.10
Descriptor: DNA (197-MER), Histone H1.10, Histone H2A type 1-B/E, ...
Authors:Zhou, B.-R, Bai, Y.
Deposit date:2020-09-17
Release date:2020-11-25
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Distinct Structures and Dynamics of Chromatosomes with Different Human Linker Histone Isoforms.
Mol.Cell, 81, 2021
5EFX
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BU of 5efx by Molmil
Crystal structure of Rho GTPase regulator
Descriptor: Rho guanine nucleotide exchange factor 2
Authors:Jiang, Y, Ouyang, S, Liu, Z.J.
Deposit date:2015-10-26
Release date:2016-06-29
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.451 Å)
Cite:Crystal structure of hGEF-H1 PH domain provides insight into incapability in phosphoinositide binding
Biochem.Biophys.Res.Commun., 471, 2016
8J7D
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BU of 8j7d by Molmil
Human 3-methylcrotonyl-CoA carboxylase in BCCP-H1 state
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial, ...
Authors:Liu, D.S, Su, J.Y.
Deposit date:2023-04-27
Release date:2024-05-08
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Human 3-methylcrotonyl-CoA carboxylase in BCCP-H1 state
To Be Published
8CEW
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BU of 8cew by Molmil
Crystal structure of human DNA cross-link repair 1A in complex with N-hydroxyimide inhibitor H1
Descriptor: 6-methoxy-2-oxidanyl-benzo[de]isoquinoline-1,3-dione, DIMETHYL SULFOXIDE, DNA cross-link repair 1A protein, ...
Authors:Newman, J.A, Yosaatmadja, Y, Baddock, H.T, Bielinski, M, von Delft, F, Bountra, C, McHugh, P.J, Schofield, C.J, Gileadi, O.
Deposit date:2023-02-02
Release date:2024-02-21
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Crystal structure of human DNA cross-link repair 1A in complex with N-hydroxyimide inhibitor H1
To Be Published
1RD8
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BU of 1rd8 by Molmil
Crystal Structure of the 1918 Human H1 Hemagglutinin Precursor (HA0)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATE ION, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Stevens, J, Corper, A.L, Basler, C.F, Taubenberger, J.K, Palese, P, Wilson, I.A.
Deposit date:2003-11-05
Release date:2004-03-23
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the Uncleaved Human H1 Hemagglutinin from the Extinct 1918 Influenza Virus.
Science, 303, 2004
6QB7
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BU of 6qb7 by Molmil
Structure of the H1 domain of human KCTD16
Descriptor: BTB/POZ domain-containing protein KCTD16, PHOSPHATE ION
Authors:Pinkas, D.M, Bufton, J.C, Williams, E.P, Strain-Damerell, C, Kupinska, K, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N, Structural Genomics Consortium (SGC)
Deposit date:2018-12-20
Release date:2019-02-06
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Structure of the H1 domain of human KCTD16
To be published
6QZL
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BU of 6qzl by Molmil
Structure of the H1 domain of human KCTD12
Descriptor: BTB/POZ domain-containing protein KCTD12
Authors:Pinkas, D.M, Bufton, J.C, Fox, A.E, Newman, J.A, Kupinska, K, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N, Structural Genomics Consortium (SGC)
Deposit date:2019-03-11
Release date:2019-03-20
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structure of the H1 domain of human KCTD12
To be published
4NYN
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BU of 4nyn by Molmil
Crystal structure of RNase H1 from halophilic archaeon Halobacterium salinarum NRC-1
Descriptor: MANGANESE (II) ION, Ribonuclease HI
Authors:You, D.J, Angkawidjaja, C, Koga, Y, Kanaya, S.
Deposit date:2013-12-11
Release date:2014-02-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Crystal structure of RNase H1 from halophilic archaeon Halobacterium salinarum NRC-1
To be Published
6NHQ
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BU of 6nhq by Molmil
Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin HA2 I45M mutant
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2018-12-23
Release date:2020-04-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Different genetic barriers for resistance to HA stem antibodies in influenza H3 and H1 viruses.
Science, 368, 2020
6NHR
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BU of 6nhr by Molmil
Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin HA2 I45F mutant
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2018-12-23
Release date:2020-04-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Different genetic barriers for resistance to HA stem antibodies in influenza H3 and H1 viruses.
Science, 368, 2020
6NHP
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BU of 6nhp by Molmil
Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin HA2 I45T mutant
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2018-12-23
Release date:2020-04-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Different genetic barriers for resistance to HA stem antibodies in influenza H3 and H1 viruses.
Science, 368, 2020
7UMM
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BU of 7umm by Molmil
H1 Solomon Islands 2006 hemagglutinin in complex with Ab109
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Windsor, I.W, Caradonna, T.M, Schmidt, A.G.
Deposit date:2022-04-07
Release date:2022-11-23
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:An epitope-enriched immunogen expands responses to a conserved viral site.
Cell Rep, 41, 2022
1UHM
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BU of 1uhm by Molmil
Solution structure of the globular domain of linker histone homolog Hho1p from S. cerevisiae
Descriptor: Histone H1
Authors:Ono, K, Kusano, O, Shimotakahara, S, Shimizu, M, Yamazaki, T, Shindo, H, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-07-05
Release date:2003-12-16
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:The linker histone homolog Hho1p from Saccharomyces cerevisiae represents a winged helix-turn-helix fold as determined by NMR spectroscopy.
Nucleic Acids Res., 31, 2003
7KBF
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BU of 7kbf by Molmil
H1.8 bound nucleosome isolated from metaphase chromosome in Xenopus egg extract (oligo fraction)
Descriptor: DNA (184-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Arimura, Y, Funabiki, H.
Deposit date:2020-10-02
Release date:2021-09-15
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (4.42 Å)
Cite:Structural features of nucleosomes in interphase and metaphase chromosomes.
Mol.Cell, 81, 2021
3F81
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BU of 3f81 by Molmil
Interaction of VHR with SA3
Descriptor: 2-[(5~{E})-5-[[3-[4-(2-fluoranylphenoxy)phenyl]-1-phenyl-pyrazol-4-yl]methylidene]-4-oxidanylidene-2-sulfanylidene-1,3-thiazolidin-3-yl]ethanesulfonic acid, Dual specificity protein phosphatase 3
Authors:Wu, S, Mutelin, T, Tautz, L.
Deposit date:2008-11-11
Release date:2009-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Multidentate small-molecule inhibitors of vaccinia H1-related (VHR) phosphatase decrease proliferation of cervix cancer cells.
J.Med.Chem., 52, 2009
8U44
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BU of 8u44 by Molmil
CryoEM structure of A/Solomon Islands/3/2006 H1 HA in complex with 05.GC.w2.3C10-H1_SI06
Descriptor: 05.GC.w2.3C10-H1_SI06 Heavy chain, 05.GC.w2.3C10-H1_SI06 Light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Moore, N, Han, J, Ward, A.B, Wilson, I.A.
Deposit date:2023-09-08
Release date:2024-06-26
Method:ELECTRON MICROSCOPY (3.41 Å)
Cite:Persistence of germinal center B cell responses after influenza virus vaccination in humans
To Be Published
3ZTN
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BU of 3ztn by Molmil
STRUCTURE OF INFLUENZA A NEUTRALIZING ANTIBODY SELECTED FROM CULTURES OF SINGLE HUMAN PLASMA CELLS IN COMPLEX WITH HUMAN H1 INFLUENZA HAEMAGGLUTININ.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FI6V3 ANTIBODY LIGHT CHAIN, ...
Authors:Hubbard, P.A, Ritchie, A.J, Corti, D, Voss, J.E, Gamblin, S.J, Codoni, G, Macagno, A, Jarrossay, D, Pinna, D, Minola, A, Vanzetta, F, Silacci, C, Fernandez-Rodriguez, B.M, Agatic, G, Giacchetto-Sasselli, I, Vachieri, S.G, Sallusto, F, Collins, P.J, Haire, L.F, Temperton, N, Langedijk, J.P.M, Skehel, J.J, Lanzavecchia, A.
Deposit date:2011-07-12
Release date:2011-08-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.001 Å)
Cite:A Neutralizing Antibody Selected from Plasma Cells that Binds to Group 1 and Group 2 Influenza a Hemagglutinins.
Science, 333, 2011
2WRG
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BU of 2wrg by Molmil
structure of H1 1918 hemagglutinin with human receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ HA1 CHAIN, HEMAGGLUTININ HA2 CHAIN, ...
Authors:Liu, J, Stevens, D.J, Haire, L.F, Walker, P.A, Coombs, P.J, Russell, R.J, Gamblin, S.J, Skehel, J.J.
Deposit date:2009-09-01
Release date:2009-09-29
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:From the Cover: Structures of Receptor Complexes Formed by Hemagglutinins from the Asian Influenza Pandemic of 1957.
Proc.Natl.Acad.Sci.USA, 106, 2009
6LA8
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BU of 6la8 by Molmil
349 bp di-nucleosome harboring cohesive DNA termini assembled with linker histone H1.0
Descriptor: CALCIUM ION, DNA (349-MER), Histone H1.0, ...
Authors:Adhireksan, Z, Lee, P.L, Sharma, D, Davey, C.A.
Deposit date:2019-11-12
Release date:2020-10-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Near-atomic resolution structures of interdigitated nucleosome fibres.
Nat Commun, 11, 2020

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