PDB: 915 resultsInfo pagesStatus searchChemie searchBIRD

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3KRW	Human GRK2 in complex with Gbetgamma subunits and balanol (soak) Descriptor: BALANOL, Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... Authors: Tesmer, J.J.G, Tesmer, V.M. Deposit date: 2009-11-19 Release date: 2010-02-16 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structure of human g protein-coupled receptor kinase 2 in complex with the kinase inhibitor balanol. J.Med.Chem., 53, 2010
3CIK	Human GRK2 in Complex with Gbetagamma subunits Descriptor: Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... Authors: Tesmer, J.J.G, Lodowski, D.T. Deposit date: 2008-03-11 Release date: 2009-02-17 Last modified: 2012-03-07 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Structure of human G protein-coupled receptor kinase 2 in complex with the kinase inhibitor balanol. J.Med.Chem., 53, 2010
3AH8	Structure of heterotrimeric G protein Galpha-q beta gamma in complex with an inhibitor YM-254890 Descriptor: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... Authors: Nishimura, A, Kitano, K, Takasaki, J, Taniguchi, M, Mizuno, N, Tago, K, Hakoshima, T, Itoh, H. Deposit date: 2010-04-20 Release date: 2010-07-21 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural basis for the specific inhibition of heterotrimeric Gq protein by a small molecule. Proc.Natl.Acad.Sci.USA, 107, 2010
2TRC	PHOSDUCIN/TRANSDUCIN BETA-GAMMA COMPLEX Descriptor: GADOLINIUM ATOM, PHOSDUCIN, TRANSDUCIN Authors: Gaudet, R, Bohm, A, Sigler, P.B. Deposit date: 1997-01-06 Release date: 1997-06-05 Last modified: 2019-08-14 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal structure at 2.4 angstroms resolution of the complex of transducin betagamma and its regulator, phosducin. Cell(Cambridge,Mass.), 87, 1996
2PBI	The multifunctional nature of Gbeta5/RGS9 revealed from its crystal structure Descriptor: GLYCEROL, Guanine nucleotide-binding protein subunit beta 5, Regulator of G-protein signaling 9 Authors: Cheever, M.L, Snyder, J.T, Gershburg, S, Siderovski, D.P, Harden, T.K, Sondek, J. Deposit date: 2007-03-28 Release date: 2008-01-29 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Crystal structure of the multifunctional Gbeta5-RGS9 complex. Nat.Struct.Mol.Biol., 15, 2008
2BCJ	Crystal Structure of G Protein-Coupled Receptor Kinase 2 in Complex with Galpha-q and Gbetagamma Subunits Descriptor: G-protein-coupled receptor kinase 2, GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... Authors: Tesmer, J.J.G. Deposit date: 2005-10-19 Release date: 2005-12-20 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (3.061 Å) Cite: Snapshot of Activated G Proteins at the Membrane: The Gq-GRK2-G Complex Science, 310, 2005
1XHM	The Crystal Structure of a Biologically Active Peptide (SIGK) Bound to a G Protein Beta:Gamma Heterodimer Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 1, SIGK Peptide Authors: Davis, T.L, Bonacci, T.M, Smrcka, A.V, Sprang, S.R. Deposit date: 2004-09-20 Release date: 2005-08-09 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structural and Molecular Characterization of a Preferred Protein Interaction Surface on G Protein betagamma Subunits. Biochemistry, 44, 2005
1TBG	BETA-GAMMA DIMER OF THE HETEROTRIMERIC G-PROTEIN TRANSDUCIN Descriptor: TRANSDUCIN Authors: Sondek, J.S, Bohm, A, Lambright, D.G, Hamm, H.E, Sigler, P.B. Deposit date: 1996-06-15 Release date: 1997-04-01 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal structure of a G-protein beta gamma dimer at 2.1A resolution. Nature, 379, 1996
1OMW	Crystal Structure of the complex between G Protein-Coupled Receptor Kinase 2 and Heterotrimeric G Protein beta 1 and gamma 2 subunits Descriptor: G-protein coupled receptor kinase 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 1 Authors: Lodowski, D.T, Pitcher, J.A, Capel, W.D, Lefkowitz, R.J, Tesmer, J.J.G. Deposit date: 2003-02-26 Release date: 2003-06-03 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Keeping G proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and G-Beta-Gamma Science, 300, 2003
1GP2	G PROTEIN HETEROTRIMER GI_ALPHA_1 BETA_1 GAMMA_2 WITH GDP BOUND Descriptor: G PROTEIN GI ALPHA 1, G PROTEIN GI BETA 1, G PROTEIN GI GAMMA 2, ... Authors: Wall, M.A, Sprang, S.R. Deposit date: 1996-11-13 Release date: 1997-02-12 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2. Cell(Cambridge,Mass.), 83, 1995
1GOT	HETEROTRIMERIC COMPLEX OF A GT-ALPHA/GI-ALPHA CHIMERA AND THE GT-BETA-GAMMA SUBUNITS Descriptor: GT-ALPHA/GI-ALPHA CHIMERA, GT-BETA, GT-GAMMA, ... Authors: Lambright, D.G, Sondek, J, Bohm, A, Skiba, N.P, Hamm, H.E, Sigler, P.B. Deposit date: 1996-08-07 Release date: 1997-03-12 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2 Å) Cite: The 2.0 A crystal structure of a heterotrimeric G protein. Nature, 379, 1996
1GG2	G PROTEIN HETEROTRIMER MUTANT GI_ALPHA_1(G203A) BETA_1 GAMMA_2 WITH GDP BOUND Descriptor: G PROTEIN GI ALPHA 1, G PROTEIN GI BETA 1, G PROTEIN GI GAMMA 2, ... Authors: Wall, M.A, Sprang, S.R. Deposit date: 1996-11-13 Release date: 1997-02-12 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.4 Å) Cite: The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2. Cell(Cambridge,Mass.), 83, 1995
1B9Y	STRUCTURAL ANALYSIS OF PHOSDUCIN AND ITS PHOSPHORYLATION-REGULATED INTERACTION WITH TRANSDUCIN BETA-GAMMA Descriptor: GADOLINIUM ATOM, PROTEIN (PHOSDUCIN), PROTEIN (TRANSDUCIN) Authors: Gaudet, R, Sigler, P.B. Deposit date: 1999-02-16 Release date: 1999-02-23 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (3 Å) Cite: A molecular mechanism for the phosphorylation-dependent regulation of heterotrimeric G proteins by phosducin. Mol.Cell, 3, 1999
1B9X	STRUCTURAL ANALYSIS OF PHOSDUCIN AND ITS PHOSPHORYLATION-REGULATED INTERACTION WITH TRANSDUCIN Descriptor: GADOLINIUM ATOM, PROTEIN (PHOSDUCIN), PROTEIN (TRANSDUCIN) Authors: Gaudet, R, Sigler, P.B. Deposit date: 1999-02-16 Release date: 1999-02-23 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (3 Å) Cite: A molecular mechanism for the phosphorylation-dependent regulation of heterotrimeric G proteins by phosducin. Mol.Cell, 3, 1999
1A0R	HETEROTRIMERIC COMPLEX OF PHOSDUCIN/TRANSDUCIN BETA-GAMMA Descriptor: FARNESYL, PHOSDUCIN, TRANSDUCIN (BETA SUBUNIT), ... Authors: Loew, A, Ho, Y.-K, Blundell, T.L, Bax, B. Deposit date: 1997-12-05 Release date: 1998-12-30 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Phosducin induces a structural change in transducin beta gamma. Structure, 6, 1998

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