3MDR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3mdr by Molmil](/molmil-images/mine/3mdr) | Tranylcypromine complex of Cytochrome P450 46A1 | Descriptor: | (1R,2S)-2-phenylcyclopropanamine, Cholesterol 24-hydroxylase, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Mast, N, Charvet, C, Pikuleva, I, Stout, C.D. | Deposit date: | 2010-03-30 | Release date: | 2010-07-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis of drug binding to CYP46A1, an enzyme that controls cholesterol turnover in the brain. J.Biol.Chem., 285, 2010
|
|
6RZQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rzq by Molmil](/molmil-images/mine/6rzq) | |
4Y45
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4y45 by Molmil](/molmil-images/mine/4y45) | |
4YI8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4yi8 by Molmil](/molmil-images/mine/4yi8) | |
8Y65
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8y65 by Molmil](/molmil-images/mine/8y65) | Cryo-EM structure of human urate transporter GLUT9 bound to substrate urate | Descriptor: | Solute carrier family 2, facilitated glucose transporter member 9, URIC ACID | Authors: | Pan, X.J, Shen, Z.L, Xu, L, Huang, G.X.Y. | Deposit date: | 2024-02-01 | Release date: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.51 Å) | Cite: | Structural basis for urate recognition and apigenin inhibition of human GLUT9. Nat Commun, 15, 2024
|
|
4Y5H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4y5h by Molmil](/molmil-images/mine/4y5h) | |
6S1U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6s1u by Molmil](/molmil-images/mine/6s1u) | Crystal structure of dimeric M-PMV protease C7A/D26N/C106A mutant in complex with inhibitor | Descriptor: | Gag-Pro-Pol polyprotein, PRO-0A1-VAL-PSA-ALA-MET-THR | Authors: | Wosicki, S, Gilski, M, Jaskolski, M, Zabranska, H, Pichova, I. | Deposit date: | 2019-06-19 | Release date: | 2019-10-16 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Comparison of a retroviral protease in monomeric and dimeric states. Acta Crystallogr D Struct Biol, 75, 2019
|
|
6S1W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6s1w by Molmil](/molmil-images/mine/6s1w) | Crystal structure of dimeric M-PMV protease D26N mutant | Descriptor: | Gag-Pro-Pol polyprotein | Authors: | Wosicki, S, Gilski, M, Jaskolski, M, Zabranska, H, Pichova, I. | Deposit date: | 2019-06-19 | Release date: | 2019-10-16 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Comparison of a retroviral protease in monomeric and dimeric states. Acta Crystallogr D Struct Biol, 75, 2019
|
|
3MH3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3mh3 by Molmil](/molmil-images/mine/3mh3) | Mutagenesis of p38 MAP kinase establishes key roles of Phe169 in function and structural dynamics and reveals a novel DFG-out state | Descriptor: | Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside | Authors: | Namboodiri, H.V, Karpusas, M, Bukhtiyarova, M, Springman, E.B. | Deposit date: | 2010-04-07 | Release date: | 2010-04-21 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Mutagenesis of p38alpha MAP kinase establishes key roles of Phe169 in function and structural dynamics and reveals a novel DFG-OUT state. Biochemistry, 46, 2007
|
|
6S2M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6s2m by Molmil](/molmil-images/mine/6s2m) | |
8Y66
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8y66 by Molmil](/molmil-images/mine/8y66) | Cryo-EM structure of human urate transporter GLUT9 bound to inhibitor apigenin | Descriptor: | 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one, Solute carrier family 2, facilitated glucose transporter member 9 | Authors: | Pan, X.J, Shen, Z.L, Xu, L, Huang, G.X.Y. | Deposit date: | 2024-02-01 | Release date: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.28 Å) | Cite: | Structural basis for urate recognition and apigenin inhibition of human GLUT9. Nat Commun, 15, 2024
|
|
3MKB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3mkb by Molmil](/molmil-images/mine/3mkb) | Crystal structure determination of Shortfin Mako (Isurus oxyrinchus) hemoglobin at 1.9 Angstrom resolution | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Ramesh, P, Sundaresan, S.S, Sathya Moorthy, P, Balasubramanian, M, Ponnuswamy, M.N. | Deposit date: | 2010-04-14 | Release date: | 2011-01-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural studies of haemoglobin from pisces species shortfin mako shark (Isurus oxyrinchus) at 1.9 angstrom resolution J.SYNCHROTRON RADIAT., 20, 2013
|
|
6S73
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6s73 by Molmil](/molmil-images/mine/6s73) | Crystal structure of Nek7 SRS mutant bound to compound 51 | Descriptor: | 3-[[6-(cyclohexylmethoxy)-7~{H}-purin-2-yl]amino]-~{N}-[3-(dimethylamino)propyl]benzenesulfonamide, Serine/threonine-protein kinase Nek7 | Authors: | Nasir, N, Byrne, M.J, Bhatia, C, Bayliss, R. | Deposit date: | 2019-07-04 | Release date: | 2020-06-10 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Nek7 conformational flexibility and inhibitor binding probed through protein engineering of the R-spine. Biochem.J., 477, 2020
|
|
4YU3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4yu3 by Molmil](/molmil-images/mine/4yu3) | |
3MM4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3mm4 by Molmil](/molmil-images/mine/3mm4) | Crystal structure of the receiver domain of the histidine kinase CKI1 from Arabidopsis thaliana | Descriptor: | Histidine kinase homolog | Authors: | Marek, J, Klumpler, T, Pekarova, B, Triskova, O, Horak, J, Zidek, L, Dopitova, R, Hejatko, J, Janda, L. | Deposit date: | 2010-04-19 | Release date: | 2011-04-13 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure and binding specificity of the receiver domain of sensor histidine kinase CKI1 from Arabidopsis thaliana. Plant J., 67, 2011
|
|
4Y8Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4y8y by Molmil](/molmil-images/mine/4y8y) | |
3MNB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3mnb by Molmil](/molmil-images/mine/3mnb) | Investigation of global and local effects of radiation damage on porcine pancreatic elastase. First stage of radiation damage | Descriptor: | Chymotrypsin-like elastase family member 1, SODIUM ION, SULFATE ION | Authors: | Petrova, T, Ginell, S, Kim, Y, Joachimiak, G, Joachimiak, A. | Deposit date: | 2010-04-21 | Release date: | 2010-05-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.198 Å) | Cite: | X-ray-induced deterioration of disulfide bridges at atomic resolution. Acta Crystallogr.,Sect.D, 66, 2010
|
|
4YVE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4yve by Molmil](/molmil-images/mine/4yve) | ROCK 1 bound to methoxyphenyl thiazole inhibitor | Descriptor: | 2-(3-methoxyphenyl)-N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl]acetamide, Rho-associated protein kinase 1 | Authors: | Jacobs, M.D. | Deposit date: | 2015-03-19 | Release date: | 2015-06-10 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Design, Synthesis, and Structure-Activity Relationships of Pyridine-Based Rho Kinase (ROCK) Inhibitors. J.Med.Chem., 58, 2015
|
|
3MBL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3mbl by Molmil](/molmil-images/mine/3mbl) | |
4Y9W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4y9w by Molmil](/molmil-images/mine/4y9w) | Aspartic Proteinase Sapp2 Secreted from Candida Parapsilosis at 0.82 A Resolution. | Descriptor: | Aspartic acid endopeptidase Sapp2, PEPTIDE | Authors: | Dostal, J, Brynda, J, Hruskova-Heidingsfeldova, O, Rezacova, P, Mareckova, L, Pichova, I. | Deposit date: | 2015-02-17 | Release date: | 2016-11-30 | Last modified: | 2019-09-04 | Method: | X-RAY DIFFRACTION (0.83 Å) | Cite: | Atomic resolution crystal structure of Sapp2p, a secreted aspartic protease from Candida parapsilosis. Acta Crystallogr.,Sect.D, 71, 2015
|
|
3MO3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3mo3 by Molmil](/molmil-images/mine/3mo3) | Investigation of global and local effects of radiation damage on porcine pancreatic elastase. Fifth stage of radiation damage | Descriptor: | Chymotrypsin-like elastase family member 1, SODIUM ION, SULFATE ION | Authors: | Petrova, T, Ginell, S, Kim, Y, Joachimiak, G, Joachimiak, A. | Deposit date: | 2010-04-22 | Release date: | 2010-05-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.805 Å) | Cite: | X-ray-induced deterioration of disulfide bridges at atomic resolution. Acta Crystallogr.,Sect.D, 66, 2010
|
|
3MO9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3mo9 by Molmil](/molmil-images/mine/3mo9) | Investigation of global and local effects of radiation damage on porcine pancreatic elastase. Seventh stage of radiation damage | Descriptor: | Chymotrypsin-like elastase family member 1, SODIUM ION, SULFATE ION | Authors: | Petrova, T, Ginell, S, Kim, Y, Joachimiak, G, Joachimiak, A. | Deposit date: | 2010-04-22 | Release date: | 2010-05-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.003 Å) | Cite: | X-ray-induced deterioration of disulfide bridges at atomic resolution. Acta Crystallogr.,Sect.D, 66, 2010
|
|
9BBB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9bbb by Molmil](/molmil-images/mine/9bbb) | Human CYP3A4 bound to an inhibitor | Descriptor: | Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, cobicistat | Authors: | Sevrioukova, I.F. | Deposit date: | 2024-04-05 | Release date: | 2024-07-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Interaction of CYP3A4 with the inhibitor cobicistat: Structural and mechanistic insights and comparison with ritonavir to be published
|
|
3MD3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3md3 by Molmil](/molmil-images/mine/3md3) | Crystal Structure of the First Two RRM Domains of Yeast Poly(U) Binding Protein (Pub1) | Descriptor: | GLYCEROL, Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1, SULFATE ION | Authors: | Li, H, Shi, H, Zhu, Z, Wang, H, Niu, L, Teng, M. | Deposit date: | 2010-03-29 | Release date: | 2010-05-05 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal Structure of the First Two RRM Domains of Yeast Poly(U) Binding Protein (Pub1) To be published
|
|
8ZMN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8zmn by Molmil](/molmil-images/mine/8zmn) | Crystal structure of ANTXR1 | Descriptor: | Anthrax toxin receptor 1, SODIUM ION | Authors: | Zheng, H, Hu, J, Fu, L, Chen, R. | Deposit date: | 2024-05-23 | Release date: | 2024-06-26 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | X-ray structure of Anthrax toxin receptor 1 APO from Rattus norvegicus To Be Published
|
|