8WTY
| Cryo-EM structure of noradrenaline transporter in complex with ziprasidone | Descriptor: | 5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloranyl-1,3-dihydroindol-2-one, Sodium-dependent noradrenaline transporter | Authors: | Zhao, Y, Hu, T, Yu, Z. | Deposit date: | 2023-10-19 | Release date: | 2024-08-07 | Last modified: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Transport and inhibition mechanisms of the human noradrenaline transporter. Nature, 632, 2024
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8WTX
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2Q8U
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5TFV
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4AP6
| Crystal structure of human POFUT2 E54A mutant in complex with GDP- fucose | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2, ... | Authors: | Chen, C, Keusch, J.J, Klein, D, Hess, D, Hofsteenge, J, Gut, H. | Deposit date: | 2012-03-30 | Release date: | 2012-08-08 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.401 Å) | Cite: | Structure of Human Pofut2: Insights Into Thrombospondin Type 1 Repeat Fold and O-Fucosylation. Embo J., 31, 2012
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7VSR
| Structure of McrBC (stalkless mutant) | Descriptor: | 5-methylcytosine-specific restriction enzyme B, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Saikrishnan, K, Adhav, V.A, Bose, S, Kutti R, V. | Deposit date: | 2021-10-27 | Release date: | 2023-02-15 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structure of McrBC (stalkless mutant) To Be Published
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8VUN
| Human GluN1-2A With Fab 008-218 | Descriptor: | 008-218 Heavy, 008-218 Light, Glutamate receptor ionotropic, ... | Authors: | Michalski, K, Furukawa, H. | Deposit date: | 2024-01-29 | Release date: | 2024-09-11 | Last modified: | 2024-09-18 | Method: | ELECTRON MICROSCOPY (4.01 Å) | Cite: | Structural and functional mechanisms of anti-NMDAR autoimmune encephalitis. Nat.Struct.Mol.Biol., 2024
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8VUQ
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8VVH
| rat GluN1a-2B Fab 003-102 local refinement | Descriptor: | 003-102 Heavy, 003-102 Light, Glutamate receptor ionotropic, ... | Authors: | Michalski, K, Furukawa, H. | Deposit date: | 2024-01-31 | Release date: | 2024-09-11 | Last modified: | 2024-09-18 | Method: | ELECTRON MICROSCOPY (3.95 Å) | Cite: | Structural and functional mechanisms of anti-NMDAR autoimmune encephalitis. Nat.Struct.Mol.Biol., 2024
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8VUL
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8VUJ
| Human GluN1-2A with Fab 003-102 | Descriptor: | 003-102 Heavy, 003-102 Light, Glutamate receptor ionotropic, ... | Authors: | Michalski, K, Furukawa, H. | Deposit date: | 2024-01-29 | Release date: | 2024-09-11 | Last modified: | 2024-09-18 | Method: | ELECTRON MICROSCOPY (3.92 Å) | Cite: | Structural and functional mechanisms of anti-NMDAR autoimmune encephalitis. Nat.Struct.Mol.Biol., 2024
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8VUT
| Human GluN1-2A with IgG 008-218 | Descriptor: | 008-218 Heavy, 008-218 Light, Glutamate receptor ionotropic, ... | Authors: | Michalski, K, Furukawa, H. | Deposit date: | 2024-01-29 | Release date: | 2024-09-11 | Last modified: | 2024-09-18 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural and functional mechanisms of anti-NMDAR autoimmune encephalitis. Nat.Struct.Mol.Biol., 2024
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8VUY
| Rat GluN1-2B with Fab 003-102 | Descriptor: | 003-102 Heavy, 003-102 Light, Glutamate receptor ionotropic, ... | Authors: | Michalski, K, Furukawa, H. | Deposit date: | 2024-01-30 | Release date: | 2024-09-11 | Last modified: | 2024-09-18 | Method: | ELECTRON MICROSCOPY (3.81 Å) | Cite: | Structural and functional mechanisms of anti-NMDAR autoimmune encephalitis. Nat.Struct.Mol.Biol., 2024
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8VUS
| Human GluN1-2A with IgG 007-168 | Descriptor: | 007-168 Heavy, 007-168 Light, Glutamate receptor ionotropic, ... | Authors: | Michalski, K, Furukawa, H. | Deposit date: | 2024-01-29 | Release date: | 2024-09-11 | Last modified: | 2024-09-18 | Method: | ELECTRON MICROSCOPY (3.99 Å) | Cite: | Structural and functional mechanisms of anti-NMDAR autoimmune encephalitis. Nat.Struct.Mol.Biol., 2024
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3ZR8
| Crystal structure of RxLR effector Avr3a11 from Phytophthora capsici | Descriptor: | AVR3A11, CHLORIDE ION, TRIETHYLENE GLYCOL | Authors: | Boutemy, L.S, King, S.R.F, Win, J, Hughes, R.K, Clarke, T.A, Blumenschein, T.M.A, Kamoun, S, Banfield, M.J. | Deposit date: | 2011-06-15 | Release date: | 2011-08-03 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (0.9 Å) | Cite: | Structures of Phytophthora Rxlr Effector Proteins: A Conserved But Adaptable Fold Underpins Functional Diversity. J.Biol.Chem., 286, 2011
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5WHR
| Discovery of a novel and selective IDO-1 inhibitor PF-06840003 and its characterization as a potential clinical candidate. | Descriptor: | (3R)-3-(5-fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione, Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Greasley, S.E, Kaiser, S.E, Feng, J.L, Stewart, A. | Deposit date: | 2017-07-18 | Release date: | 2017-12-27 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Discovery of a Novel and Selective Indoleamine 2,3-Dioxygenase (IDO-1) Inhibitor 3-(5-Fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione (EOS200271/PF-06840003) and Its Characterization as a Potential Clinical Candidate. J. Med. Chem., 60, 2017
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4CEL
| ACTIVE-SITE MUTANT D214N DETERMINED AT PH 6.0 WITH NO LIGAND BOUND IN THE ACTIVE SITE | Descriptor: | 1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE I, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION | Authors: | Divne, C, Stahlberg, J, Jones, T.A. | Deposit date: | 1996-08-24 | Release date: | 1997-03-12 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Activity studies and crystal structures of catalytically deficient mutants of cellobiohydrolase I from Trichoderma reesei. J.Mol.Biol., 264, 1996
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6MQF
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4LYO
| CROSS-LINKED CHICKEN LYSOZYME CRYSTAL IN NEAT ACETONITRILE, THEN BACK-SOAKED IN WATER | Descriptor: | LYSOZYME | Authors: | Huang, Q, Wang, Z, Zhu, G, Qian, M, Shao, M, Jia, Y, Tang, Y. | Deposit date: | 1998-03-11 | Release date: | 1998-05-27 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | X-ray studies on cross-linked lysozyme crystals in acetonitrile-water mixture. Biochim.Biophys.Acta, 1384, 1998
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4MHI
| Crystal structure of a H5N1 influenza virus hemagglutinin from A/goose/Guangdong/1/96 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... | Authors: | Zhu, X, Wilson, I.A. | Deposit date: | 2013-08-29 | Release date: | 2013-10-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.595 Å) | Cite: | A Unique and Conserved Neutralization Epitope in H5N1 Influenza Viruses Identified by an Antibody against the A/Goose/Guangdong/1/96 Hemagglutinin. J.Virol., 87, 2013
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2WB2
| Drosophila Melanogaster (6-4) Photolyase Bound To double stranded Dna containing a T(6-4)C Photolesion | Descriptor: | 5'-D(*AP*CP*AP*GP*CP*GP*GP*64PP*ZP*GP*CP*AP *GP*GP*T)-3', 5'-D(*TP*AP*CP*CP*TP*GP*CP*GP*AP*CP*CP*GP*CP*TP*G)-3', FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Glas, A.F, Schneider, S, Maul, M.J, Hennecke, U, Carell, T. | Deposit date: | 2009-02-20 | Release date: | 2009-03-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Crystal Structure of the T(6-4)C Lesion in Complex with a (6-4) DNA Photolyase and Repair of Uv- Induced (6-4) and Dewar Photolesions. Chemistry, 15, 2009
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4HTQ
| Mitigation of X-ray damage in macromolecular crystallography by submicrometer line focusing; total dose 6.70 x 10e+11 X-ray photons | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C, ... | Authors: | Duke, N.E.C, Finfrock, Y.Z, Stern, E.Z, Alkire, R.W, Lazarski, K, Joachimiak, A. | Deposit date: | 2012-11-01 | Release date: | 2013-05-15 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (1.399 Å) | Cite: | Mitigation of X-ray damage in macromolecular crystallography by submicrometre line focusing. Acta Crystallogr.,Sect.D, 69, 2013
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3VX6
| Crystal structure of Kluyveromyces marxianus Atg7NTD | Descriptor: | E1 | Authors: | Yamaguchi, M, Matoba, K, Sawada, R, Fujioka, Y, Nakatogawa, H, Yamamoto, H, Kobashigawa, Y, Hoshida, H, Akada, R, Ohsumi, Y, Noda, N.N, Inagaki, F. | Deposit date: | 2012-09-11 | Release date: | 2012-11-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Noncanonical recognition and UBL loading of distinct E2s by autophagy-essential Atg7. Nat.Struct.Mol.Biol., 19, 2012
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3VX7
| Crystal structure of Kluyveromyces marxianus Atg7NTD-Atg10 complex | Descriptor: | E1, E2 | Authors: | Yamaguchi, M, Matoba, K, Sawada, R, Fujioka, Y, Nakatogawa, H, Yamamoto, H, Kobashigawa, Y, Hoshida, H, Akada, R, Ohsumi, Y, Noda, N.N, Inagaki, F. | Deposit date: | 2012-09-11 | Release date: | 2012-11-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Noncanonical recognition and UBL loading of distinct E2s by autophagy-essential Atg7. Nat.Struct.Mol.Biol., 19, 2012
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2VNJ
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