8VUQ
Human GluN1-2A with Fab 008-218 Local refinement of ATD
Summary for 8VUQ
Entry DOI | 10.2210/pdb8vuq/pdb |
EMDB information | 43536 |
Descriptor | Glutamate receptor ionotropic, NMDA 1, Glutamate receptor ionotropic, NMDA 2A, 008-218 Heavy, ... (4 entities in total) |
Functional Keywords | channel, heterotetramer, receptor, antibody, membrane protein-immune system complex, membrane protein/immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 128005.47 |
Authors | Michalski, K.,Furukawa, H. (deposition date: 2024-01-29, release date: 2024-09-11, Last modification date: 2024-09-18) |
Primary citation | Michalski, K.,Abdulla, T.,Kleeman, S.,Schmidl, L.,Gomez, R.,Simorowski, N.,Vallese, F.,Pruss, H.,Heckmann, M.,Geis, C.,Furukawa, H. Structural and functional mechanisms of anti-NMDAR autoimmune encephalitis. Nat.Struct.Mol.Biol., 2024 Cited by PubMed: 39227719DOI: 10.1038/s41594-024-01386-4 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.85 Å) |
Structure validation
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