4YGD
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![BU of 4ygd by Molmil](/molmil-images/mine/4ygd) | Crystal structure of ERGIC-53/MCFD2, monoclinic calcium-bound form 2 | Descriptor: | CALCIUM ION, CHLORIDE ION, Multiple coagulation factor deficiency protein 2, ... | Authors: | Satoh, T, Nishio, M, Yagi-Utsumi, M, Suzuki, K, Anzai, T, Mizushima, T, Kamiya, Y, Kato, K. | Deposit date: | 2015-02-26 | Release date: | 2016-04-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Crystallographic snapshots of the EF-hand protein MCFD2 complexed with the intracellular lectin ERGIC-53 involved in glycoprotein transport. Acta Crystallogr.,Sect.F, 76, 2020
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4YGC
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![BU of 4ygc by Molmil](/molmil-images/mine/4ygc) | Crystal structure of ERGIC-53/MCFD2, monoclinic calcium-bound form 1 | Descriptor: | CALCIUM ION, CHLORIDE ION, Multiple coagulation factor deficiency protein 2, ... | Authors: | Satoh, T, Nishio, M, Yagi-Utsumi, M, Suzuki, K, Anzai, T, Mizushima, T, Kamiya, Y, Kato, K. | Deposit date: | 2015-02-26 | Release date: | 2016-04-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystallographic snapshots of the EF-hand protein MCFD2 complexed with the intracellular lectin ERGIC-53 involved in glycoprotein transport. Acta Crystallogr.,Sect.F, 76, 2020
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7W6P
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![BU of 7w6p by Molmil](/molmil-images/mine/7w6p) | Cryo-EM structure of the alpha2A adrenergic receptor GoA signaling complex bound to a G protein biased agonist | Descriptor: | Alpha-2A adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Xu, J, Fink, E.A, Shoichet, B.K, Du, Y. | Deposit date: | 2021-12-02 | Release date: | 2022-09-28 | Last modified: | 2022-10-12 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | Structure-based discovery of nonopioid analgesics acting through the alpha 2A -adrenergic receptor. Science, 377, 2022
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7W7E
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![BU of 7w7e by Molmil](/molmil-images/mine/7w7e) | Cryo-EM structure of the alpha2A adrenergic receptor GoA signaling complex bound to a biased agonist | Descriptor: | 5-(3-bicyclo[4.2.0]octa-1,3,5-trienyl)-1,2,3,6-tetrahydropyridine, Alpha-2A adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Xu, J, Fink, E.A, Shoichet, B.K, Du, Y. | Deposit date: | 2021-12-04 | Release date: | 2022-09-28 | Last modified: | 2022-10-12 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structure-based discovery of nonopioid analgesics acting through the alpha 2A -adrenergic receptor. Science, 377, 2022
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5EM0
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![BU of 5em0 by Molmil](/molmil-images/mine/5em0) | Crystal structure of mugwort allergen Art v 4 | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Pollen allergen Art v 4.01, SODIUM ION | Authors: | Offermann, L.R, Perdue, M.L, Chruszcz, M. | Deposit date: | 2015-11-05 | Release date: | 2016-06-08 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Structural, Functional, and Immunological Characterization of Profilin Panallergens Amb a 8, Art v 4, and Bet v 2. J.Biol.Chem., 291, 2016
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4YGE
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![BU of 4yge by Molmil](/molmil-images/mine/4yge) | Crystal structure of ERGIC-53/MCFD2, trigonal calcium-bound form 2 | Descriptor: | CALCIUM ION, CHLORIDE ION, Multiple coagulation factor deficiency protein 2, ... | Authors: | Satoh, T, Nishio, M, Yagi-Utsumi, M, Suzuki, K, Anzai, T, Mizushima, T, Kamiya, Y, Kato, K. | Deposit date: | 2015-02-26 | Release date: | 2016-04-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Crystallographic snapshots of the EF-hand protein MCFD2 complexed with the intracellular lectin ERGIC-53 involved in glycoprotein transport. Acta Crystallogr.,Sect.F, 76, 2020
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2CFE
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![BU of 2cfe by Molmil](/molmil-images/mine/2cfe) | The 1.5 A crystal structure of the Malassezia sympodialis Mala s 6 allergen, a member of the cyclophilin pan-allergen family | Descriptor: | ALANINE, ALLERGEN, GLYCEROL, ... | Authors: | Limacher, A, Glaser, A.G, Fluckiger, S, Scheynius, A, Scapozza, L, Crameri, R. | Deposit date: | 2006-02-20 | Release date: | 2006-02-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Analysis of the cross-reactivity and of the 1.5 A crystal structure of the Malassezia sympodialis Mala s 6 allergen, a member of the cyclophilin pan-allergen family. Biochem. J., 396, 2006
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2YCZ
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![BU of 2ycz by Molmil](/molmil-images/mine/2ycz) | TURKEY BETA1 ADRENERGIC RECEPTOR WITH STABILISING MUTATIONS AND BOUND ANTAGONIST IODOCYANOPINDOLOL | Descriptor: | 4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3-iodo-1H-indole-2-carbonitrile, BETA-1 ADRENERGIC RECEPTOR, octyl 1-thio-beta-D-glucopyranoside | Authors: | Moukhametzianov, R, Warne, T, Edwards, P.C, Serrano-Vega, M.J, Leslie, A.G.W, Tate, C.G, Schertler, G.F.X. | Deposit date: | 2011-03-17 | Release date: | 2011-06-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.65 Å) | Cite: | Two Distinct Conformations of Helix 6 Observed in Antagonist-Bound Structures of a {Beta}1- Adrenergic Receptor. Proc.Natl.Acad.Sci.USA, 108, 2011
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5X7Y
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![BU of 5x7y by Molmil](/molmil-images/mine/5x7y) | Crystal Structure of the Dog Lipocalin Allergen Can f 6 | Descriptor: | DI(HYDROXYETHYL)ETHER, Lipocalin-Can f 6 allergen | Authors: | Yamamoto, K, Otani, T, Sugiura, K, Nakatsuji, M, Nishimura, S, Inui, T. | Deposit date: | 2017-02-28 | Release date: | 2018-04-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Crystal structure of the dog allergen Can f 6 and structure-based implications of its cross-reactivity with the cat allergen Fel d 4. Sci Rep, 9, 2019
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2YCW
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![BU of 2ycw by Molmil](/molmil-images/mine/2ycw) | TURKEY BETA1 ADRENERGIC RECEPTOR WITH STABILISING MUTATIONS AND BOUND ANTAGONIST CARAZOLOL | Descriptor: | (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol, BETA-1 ADRENERGIC RECEPTOR, HEGA-10, ... | Authors: | Moukhametzianov, R, Warne, T, Edwards, P.C, Serrano-Vega, M.J, Leslie, A.G.W, Tate, C.G, Schertler, G.F.X. | Deposit date: | 2011-03-17 | Release date: | 2011-06-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Two Distinct Conformations of Helix 6 Observed in Antagonist-Bound Structures of a Beta-1- Adrenergic Receptor. Proc.Natl.Acad.Sci.USA, 108, 2011
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7XJH
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![BU of 7xjh by Molmil](/molmil-images/mine/7xjh) | Isoproterenol-activated dog beta3 adrenergic receptor | Descriptor: | Beta-3 adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Shihoya, W, Nureki, O. | Deposit date: | 2022-04-18 | Release date: | 2022-05-04 | Last modified: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structure of the beta 3-adrenergic receptor reveals the molecular basis of subtype selectivity. Mol.Cell, 81, 2021
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2VXQ
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![BU of 2vxq by Molmil](/molmil-images/mine/2vxq) | Crystal structure of the major grass pollen allergen Phl p 2 in complex with its specific IgE-Fab | Descriptor: | FAB, POLLEN ALLERGEN PHL P 2 | Authors: | Padavattan, S, Flicker, S, Schirmer, T, Madritsch, C, Randow, S, Reese, G, Vieths, S, Lupinek, C, Ebner, C, Valenta, R, Markovic-Housley, Z. | Deposit date: | 2008-07-08 | Release date: | 2009-02-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | High-Affinity Ige Recognition of a Conformational Epitope of the Major Respiratory Allergen Phl P 2 as Revealed by X-Ray Crystallography. J.Immunol., 182, 2009
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1GV9
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![BU of 1gv9 by Molmil](/molmil-images/mine/1gv9) | p58/ERGIC-53 | Descriptor: | P58/ERGIC-53, SULFATE ION | Authors: | Velloso, L.M, Svensson, K, Schneider, G, Pettersson, R.F, Lindqvist, Y. | Deposit date: | 2002-02-07 | Release date: | 2002-02-28 | Last modified: | 2018-01-17 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Crystal Structure of the Carbohydrate Recognition Domain of P58/Ergic-53, a Protein Involved in Glycoprotein Export from the Endoplasmic Reticulum. J.Biol.Chem., 277, 2002
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3L4R
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![BU of 3l4r by Molmil](/molmil-images/mine/3l4r) | Crystal structure of the dog lipocalin allergen Can f 2 and implications for cross-reactivity to the cat allergen Fel d 4 | Descriptor: | GLYCEROL, Minor allergen Can f 2 | Authors: | Madhurantakam, C, Nilsson, O.B, Gronlund, H, Achour, A. | Deposit date: | 2009-12-21 | Release date: | 2010-05-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Crystal Structure of the Dog Lipocalin Allergen Can f 2: Implications for Cross-reactivity to the Cat Allergen Fel d 4 J.Mol.Biol., 401, 2010
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1NLX
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![BU of 1nlx by Molmil](/molmil-images/mine/1nlx) | Crystal Structure of PHL P 6, A Major Timothy Grass Pollen Allergen Co-Crystallized with Zinc | Descriptor: | ARSENIC, Pollen allergen Phl p 6, ZINC ION | Authors: | Fedorov, A.A, Ball, T, Fedorov, E.V, Vrtala, S, Valenta, R, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2003-01-07 | Release date: | 2003-01-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structure oh Phl p 6, a major timothy grass pollen allergen co-crystallized with Zinc To be Published
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1PUO
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![BU of 1puo by Molmil](/molmil-images/mine/1puo) | Crystal structure of Fel d 1- the major cat allergen | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Major allergen I polypeptide, fused chain 2, ... | Authors: | Kaiser, L, Gronlund, H, Sandalova, T, Ljunggren, H.G, van Hage-Hamsten, M, Achour, A, Schneider, G. | Deposit date: | 2003-06-25 | Release date: | 2003-10-14 | Last modified: | 2019-07-03 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The crystal structure of the major cat allergen Fel d 1, a member of the secretoglobin family. J.Biol.Chem., 278, 2003
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3D4S
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![BU of 3d4s by Molmil](/molmil-images/mine/3d4s) | Cholesterol bound form of human beta2 adrenergic receptor. | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol, Beta-2 adrenergic receptor/T4-lysozyme chimera, ... | Authors: | Hanson, M.A, Cherezov, V, Roth, C.B, Griffith, M.T, Jaakola, V.-P, Chien, E.Y.T, Velasquez, J, Kuhn, P, Stevens, R.C, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), GPCR Network (GPCR) | Deposit date: | 2008-05-14 | Release date: | 2008-06-17 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A specific cholesterol binding site is established by the 2.8 A structure of the human beta2-adrenergic receptor. Structure, 16, 2008
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2B5S
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![BU of 2b5s by Molmil](/molmil-images/mine/2b5s) | Crystal structure of peach Pru p3, the prototypic member of the family of plant non-specific lipid transfer protein pan-allergens | Descriptor: | HEPTANE, LAURIC ACID, Non-specific lipid transfer protein, ... | Authors: | Pasquato, N, Berni, R, Folli, C, Folloni, S, Cianci, M, Pantano, S, Helliwell, R.J, Zanotti, G. | Deposit date: | 2005-09-29 | Release date: | 2005-11-29 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Crystal Structure of Peach Pru p 3, the Prototypic Member of the Family of Plant Non-specific Lipid Transfer Protein Pan-allergens J.Mol.Biol., 356, 2006
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2F08
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![BU of 2f08 by Molmil](/molmil-images/mine/2f08) | Crystal structure of a major house dust mite allergen, Derf 2 | Descriptor: | O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL, mite allergen Der f II | Authors: | Mikami, B, Tanaka, Y, Minato, N, Suzuki, M, Korematsu, S. | Deposit date: | 2005-11-12 | Release date: | 2005-11-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure and some properties of a major house dust mite allergen, Derf 2 Biochem.Biophys.Res.Commun., 339, 2006
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1WRF
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![BU of 1wrf by Molmil](/molmil-images/mine/1wrf) | Refined solution structure of Der f 2, The Major Mite Allergen from Dermatophagoides farinae | Descriptor: | Mite group 2 allergen Der f 2 | Authors: | Ichikawa, S, Takai, T, Inoue, T, Yuuki, T, Okumura, Y, Ogura, K, Inagaki, F, Hatanaka, H. | Deposit date: | 2004-10-15 | Release date: | 2005-04-19 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | NMR Study on the Major Mite Allergen Der f 2: Its Refined Tertiary Structure, Epitopes for Monoclonal Antibodies and Characteristics Shared by ML Protein Group Members J.Biochem.(Tokyo), 137, 2005
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2VZN
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![BU of 2vzn by Molmil](/molmil-images/mine/2vzn) | |
7XJI
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![BU of 7xji by Molmil](/molmil-images/mine/7xji) | Solabegron-activated dog beta3 adrenergic receptor | Descriptor: | 3-[3-[2-[[(2~{S})-2-(3-chlorophenyl)-2-oxidanyl-ethyl]amino]ethylamino]phenyl]benzoic acid, Beta-3 adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Shihoya, W, Nureki, O. | Deposit date: | 2022-04-18 | Release date: | 2022-05-04 | Last modified: | 2022-06-29 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cryo-EM structures of the beta 3 adrenergic receptor bound to solabegron and isoproterenol. Biochem.Biophys.Res.Commun., 611, 2022
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1PXZ
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![BU of 1pxz by Molmil](/molmil-images/mine/1pxz) | 1.7 Angstrom Crystal Structure of jun a 1, the major allergen from cedar pollen | Descriptor: | Major pollen allergen Jun a 1 | Authors: | Czerwinski, E.W, White, M.A, Midoro-Horiuti, T, Brooks, E.G, Goldblum, R.M. | Deposit date: | 2003-07-07 | Release date: | 2004-11-16 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of Jun a 1, the major cedar pollen allergen from Juniperus ashei, reveals a parallel beta-helical core. J.Biol.Chem., 280, 2005
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2YCX
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![BU of 2ycx by Molmil](/molmil-images/mine/2ycx) | TURKEY BETA1 ADRENERGIC RECEPTOR WITH STABILISING MUTATIONS AND BOUND ANTAGONIST CYANOPINDOLOL | Descriptor: | 4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile, BETA-1 ADRENERGIC RECEPTOR, octyl 1-thio-beta-D-glucopyranoside | Authors: | Moukhametzianov, R, Warne, T, Edwards, P.C, Serrano-Vega, M.J, Leslie, A.G.W, Tate, C.G, Schertler, G.F.X. | Deposit date: | 2011-03-17 | Release date: | 2011-06-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Two Distinct Conformations of Helix 6 Observed in Antagonist-Bound Structures of a Beta-1- Adrenergic Receptor. Proc.Natl.Acad.Sci.USA, 108, 2011
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2YCY
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![BU of 2ycy by Molmil](/molmil-images/mine/2ycy) | TURKEY BETA1 ADRENERGIC RECEPTOR WITH STABILISING MUTATIONS AND BOUND ANTAGONIST CYANOPINDOLOL | Descriptor: | 4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile, BETA-1 ADRENERGIC RECEPTOR, SODIUM ION, ... | Authors: | Moukhametzianov, R, Warne, T, Edwards, P.C, Serrano-Vega, M.J, Leslie, A.G.W, Tate, C.G, Schertler, G.F.X. | Deposit date: | 2011-03-17 | Release date: | 2011-06-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Two Distinct Conformations of Helix 6 Observed in Antagonist-Bound Structures of a {Beta}1- Adrenergic Receptor. Proc.Natl.Acad.Sci.USA, 108, 2011
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