7XJI

Solabegron-activated dog beta3 adrenergic receptor

Summary for 7XJI

• Entry DOI: 10.2210/pdb7xji/pdb
• EMDB information: 33228
• Descriptor: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Nanobody-35, ... (6 entities in total)
• Functional Keywords: gpcr, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 148415.63

Authors

Shihoya, W.,Nureki, O. (deposition date: 2022-04-18, release date: 2022-05-04, Last modification date: 2022-06-29)

• Primary citation: Nureki, I.,Kobayashi, K.,Tanaka, T.,Demura, K.,Inoue, A.,Shihoya, W.,Nureki, O.; Cryo-EM structures of the beta 3 adrenergic receptor bound to solabegron and isoproterenol.; Biochem.Biophys.Res.Commun., 611:158-164, 2022; PubMed: 35489202; DOI: 10.1016/j.bbrc.2022.04.065

Experimental method

ELECTRON MICROSCOPY (3.9 Å)