8EZJ
 
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8ILL
 | | Crystal structure of a highly photostable and bright green fluorescent protein at pH5.6 | | Descriptor: | CHLORIDE ION, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose, green fluorescent protein | | Authors: | Ago, H, Ando, R, Hirano, M, Shimozono, S, Miyawaki, A, Yamamoto, M. | | Deposit date: | 2023-03-03 | | Release date: | 2023-10-04 | | Last modified: | 2024-04-24 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | StayGold variants for molecular fusion and membrane-targeting applications.
Nat.Methods, 21, 2024
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8ILK
 | | Crystal structure of a highly photostable and bright green fluorescent protein at pH8.5 | | Descriptor: | CHLORIDE ION, Green FLUORESCENT PROTEIN | | Authors: | Ago, H, Ando, R, Hirano, M, Shimozono, S, Miyawaki, A, Yamamoto, M. | | Deposit date: | 2023-03-03 | | Release date: | 2023-10-04 | | Last modified: | 2024-04-24 | | Method: | X-RAY DIFFRACTION (1.56 Å) | | Cite: | StayGold variants for molecular fusion and membrane-targeting applications.
Nat.Methods, 21, 2024
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8EXW
 | | Drosophila melanogaster indirect flight muscle myosin II (subfragment-1) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Isoform K of Myosin heavy chain, muscle, ... | | Authors: | Caldwell, J.T, Huxford, T, Bernstein, S.I, Stec, B. | | Deposit date: | 2022-10-25 | | Release date: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Drosophila melanogaster indirect flight muscle myosin II (subfragment-1)
To Be Published
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7ZOZ
 | | Crystal structure of Siglec-15 in complex with Fab | | Descriptor: | Anti-Siglec 15 Fab HC, Anti-Siglec 15 Fab LC, Sialic acid-binding Ig-like lectin 15 | | Authors: | Lenza, M.P, Oyenarte, I, Jimenez-Barbero, J, Ereno-Orbea, J. | | Deposit date: | 2022-04-26 | | Release date: | 2023-06-28 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.104 Å) | | Cite: | Structural insights into Siglec-15 reveal glycosylation dependency for its interaction with T cells through integrin CD11b.
Nat Commun, 14, 2023
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8HUG
 | | F1 in complex with CRM1-Ran-RanBP1 | | Descriptor: | 4-[4-(3-chlorophenyl)piperazin-1-yl]-3-[(3-fluorophenyl)sulfonylamino]benzoic acid, CHLORIDE ION, CRM1 isoform 1, ... | | Authors: | Sun, Q, Lei, Y. | | Deposit date: | 2022-12-23 | | Release date: | 2023-12-27 | | Last modified: | 2024-07-10 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Discovery of a Hidden Pocket beneath the NES Groove by Novel Noncovalent CRM1 Inhibitors.
J.Med.Chem., 66, 2023
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8HUF
 | | B28 in complex with CRM1-Ran-RanBP1 | | Descriptor: | 3-[(4-chlorophenyl)carbonylamino]-4-[4-(2,5-dimethylphenyl)piperazin-1-yl]benzoic acid, BROMIDE ION, CHLORIDE ION, ... | | Authors: | Sun, Q, Lei, Y. | | Deposit date: | 2022-12-23 | | Release date: | 2023-12-27 | | Last modified: | 2024-07-10 | | Method: | X-RAY DIFFRACTION (2.29 Å) | | Cite: | Discovery of a Hidden Pocket beneath the NES Groove by Novel Noncovalent CRM1 Inhibitors.
J.Med.Chem., 66, 2023
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7SWG
 | | cTnC-TnI chimera complexed with A1 | | Descriptor: | 4-(3-cyano-3-methylazetidine-1-carbonyl)-N-[(3S)-7-fluoro-6-methyl-3,4-dihydro-2H-1-benzopyran-3-yl]-5-methyl-1H-pyrrole-2-sulfonamide, Troponin C, slow skeletal and cardiac muscles,Troponin I, ... | | Authors: | Poppe, L, Hartman, J.J, Romero, A, Reagan, J.D. | | Deposit date: | 2021-11-19 | | Release date: | 2022-04-06 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural and Thermodynamic Model for the Activation of Cardiac Troponin.
Biochemistry, 61, 2022
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7SXD
 | | NMR solution structure TnC-TnI chimera | | Descriptor: | Troponin C, slow skeletal and cardiac muscles,Troponin I, cardiac muscle chimera | | Authors: | Poppe, L, Hartman, J.J, Romero, A, Reagan, J.D. | | Deposit date: | 2021-11-22 | | Release date: | 2022-04-06 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural and Thermodynamic Model for the Activation of Cardiac Troponin.
Biochemistry, 61, 2022
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7ZU0
 | | HOPS tethering complex from yeast | | Descriptor: | E3 ubiquitin-protein ligase PEP5, Vacuolar membrane protein PEP3, Vacuolar morphogenesis protein 6, ... | | Authors: | Shvarev, D, Schoppe, J, Koenig, C, Perz, A, Fuellbrunn, N, Kiontke, S, Langemeyer, L, Januliene, D, Schnelle, K, Kuemmel, D, Froehlich, F, Moeller, A, Ungermann, C. | | Deposit date: | 2022-05-11 | | Release date: | 2022-09-28 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | Structure of the endosomal CORVET tethering complex.
Nat Commun, 15, 2024
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7SXC
 | | cTnC-TnI chimera complexed with calcium | | Descriptor: | CALCIUM ION, Troponin C, slow skeletal and cardiac muscles,Troponin I, ... | | Authors: | Poppe, L, Hartman, J.J, Romero, A, Reagan, J.D. | | Deposit date: | 2021-11-22 | | Release date: | 2022-04-06 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural and Thermodynamic Model for the Activation of Cardiac Troponin.
Biochemistry, 61, 2022
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8IL8
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2DM3
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8I3V
 | | Cryo-EM structure of human norepinephrine transporter NET in the presence of the antidepressant escitalopram in an inward-open state at resolution of 2.85 angstrom. | | Descriptor: | (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile, CHLORIDE ION, Sodium-dependent noradrenaline transporter | | Authors: | Tan, J, Xiao, Y, Kong, F, Lei, J, Yuan, Y, Yan, C. | | Deposit date: | 2023-01-18 | | Release date: | 2024-07-03 | | Last modified: | 2024-09-04 | | Method: | ELECTRON MICROSCOPY (2.85 Å) | | Cite: | Molecular basis of human noradrenaline transporter reuptake and inhibition.
Nature, 632, 2024
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2EFL
 | | Crystal structure of the EFC domain of formin-binding protein 17 | | Descriptor: | Formin-binding protein 1 | | Authors: | Shimada, A, Niwa, H, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-02-23 | | Release date: | 2007-05-29 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.61 Å) | | Cite: | Curved EFC/F-BAR-Domain Dimers Are Joined End to End into a Filament for Membrane Invagination in Endocytosis
Cell(Cambridge,Mass.), 129, 2007
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8IVZ
 | | Crystal structure of talin R7 in complex with KANK1 KN motif | | Descriptor: | KN motif and ankyrin repeat domains 1, Talin-1 | | Authors: | Xu, Y, Li, K, Wei, Z, Cong, Y. | | Deposit date: | 2023-03-29 | | Release date: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | KANK1 shapes focal adhesions by orchestrating protein binding, mechanical force sensing, and phase separation.
Cell Rep, 42, 2023
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8IWT
 | | hSPCA1 in the early E2P state | | Descriptor: | BERYLLIUM TRIFLUORIDE ION, Calcium-transporting ATPase type 2C member 1, MAGNESIUM ION | | Authors: | Liu, Z.M, Wu, M.Q, Wu, C. | | Deposit date: | 2023-03-31 | | Release date: | 2023-12-27 | | Method: | ELECTRON MICROSCOPY (3.25 Å) | | Cite: | Structure and transport mechanism of the human calcium pump SPCA1.
Cell Res., 33, 2023
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8IWU
 | | hSPCA1 in the E2~P state | | Descriptor: | Calcium-transporting ATPase type 2C member 1, MAGNESIUM ION, TETRAFLUOROALUMINATE ION | | Authors: | Liu, Z.M, Wu, M.Q, Wu, C. | | Deposit date: | 2023-03-31 | | Release date: | 2023-12-27 | | Method: | ELECTRON MICROSCOPY (3.31 Å) | | Cite: | Structure and transport mechanism of the human calcium pump SPCA1.
Cell Res., 33, 2023
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8IWW
 | | hSPCA1 in the CaE1P-ADP state | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Calcium-transporting ATPase type 2C member 1, ... | | Authors: | Liu, Z.M, Wu, M.Q, Wu, C. | | Deposit date: | 2023-03-31 | | Release date: | 2023-12-27 | | Method: | ELECTRON MICROSCOPY (3.71 Å) | | Cite: | Structure and transport mechanism of the human calcium pump SPCA1.
Cell Res., 33, 2023
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8IWS
 | | hSPCA1 in the CaE2P state | | Descriptor: | BERYLLIUM TRIFLUORIDE ION, CALCIUM ION, Calcium-transporting ATPase type 2C member 1, ... | | Authors: | Liu, Z.M, Wu, M.Q, Wu, C. | | Deposit date: | 2023-03-31 | | Release date: | 2023-12-27 | | Method: | ELECTRON MICROSCOPY (3.42 Å) | | Cite: | Structure and transport mechanism of the human calcium pump SPCA1.
Cell Res., 33, 2023
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8IWR
 | | hSPCA1 in the CaE1-ATP state | | Descriptor: | CALCIUM ION, Calcium-transporting ATPase type 2C member 1, MAGNESIUM ION, ... | | Authors: | Liu, Z.M, Wu, M.Q, Wu, C. | | Deposit date: | 2023-03-31 | | Release date: | 2023-12-27 | | Method: | ELECTRON MICROSCOPY (3.52 Å) | | Cite: | Structure and transport mechanism of the human calcium pump SPCA1.
Cell Res., 33, 2023
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8IWP
 | | hSPCA1 in the CaE1 state | | Descriptor: | CALCIUM ION, Calcium-transporting ATPase type 2C member 1 | | Authors: | Liu, Z.M, Wu, M.Q, Wu, C. | | Deposit date: | 2023-03-30 | | Release date: | 2023-12-27 | | Method: | ELECTRON MICROSCOPY (3.59 Å) | | Cite: | Structure and transport mechanism of the human calcium pump SPCA1.
Cell Res., 33, 2023
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8FO2
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8FO8
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8FO9
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