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8FWJ
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BU of 8fwj by Molmil
Structure of dodecameric KaiC-RS-S413E/S414E complexed with KaiB-RS solved by cryo-EM
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein KaiB, ...
Authors:Padua, R.A.P, Grant, T, Pitsawong, W, Hoemberger, M.S, Otten, R, Bradshaw, N, Grigorieff, N, Kern, D.
Deposit date:2023-01-22
Release date:2023-03-22
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:From primordial clocks to circadian oscillators.
Nature, 616, 2023
3IYD
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BU of 3iyd by Molmil
Three-dimensional EM structure of an intact activator-dependent transcription initiation complex
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator, DNA (98-MER), ...
Authors:Hudson, B.P, Quispe, J, Lara, S, Kim, Y, Berman, H, Arnold, E, Ebright, R.H, Lawson, C.L.
Deposit date:2009-08-01
Release date:2009-11-10
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (19.799999 Å)
Cite:Three-dimensional EM structure of an intact activator-dependent transcription initiation complex
Proc.Natl.Acad.Sci.USA, 106, 2009
8B0F
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BU of 8b0f by Molmil
CryoEM structure of C5b8-CD59
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Bubeck, D, Couves, E.C, Gardner, S.
Deposit date:2022-09-07
Release date:2023-02-22
Last modified:2023-03-01
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis for membrane attack complex inhibition by CD59.
Nat Commun, 14, 2023
6PAJ
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BU of 6paj by Molmil
Structure of the SrrAB Histidine Kinase DHp-CA domain
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Sensor protein SrrB
Authors:Lopez Redondo, M.L, Marina Moreno, A.
Deposit date:2019-06-11
Release date:2020-04-22
Last modified:2020-06-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:The SrrAB two-component system regulatesStaphylococcus aureuspathogenicity through redox sensitive cysteines.
Proc.Natl.Acad.Sci.USA, 117, 2020
8G9B
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BU of 8g9b by Molmil
Human IMPDH2 mutant - L245P, treated with GTP, ATP, IMP, and NAD+; compressed filament segment reconstruction
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ...
Authors:O'Neill, A.G, Kollman, J.M.
Deposit date:2023-02-21
Release date:2023-04-19
Last modified:2023-08-09
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Neurodevelopmental disorder mutations in the purine biosynthetic enzyme IMPDH2 disrupt its allosteric regulation.
J.Biol.Chem., 299, 2023
8V5D
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BU of 8v5d by Molmil
Human mitochondrial DNA polymerase catalytic subunit, PolG, in an APO conformation
Descriptor: DNA polymerase subunit gamma-1
Authors:Riccio, A.A, Brannon, A.J, Krahn, J.M, Bouvette, J, Borgnia, J.M, Copeland, W.C.
Deposit date:2023-11-30
Release date:2024-07-10
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Coordinated DNA polymerization by Pol gamma and the region of LonP1 regulated proteolysis.
Nucleic Acids Res., 2024
8FWI
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BU of 8fwi by Molmil
Structure of dodecameric KaiC-RS-S413E/S414E solved by cryo-EM
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein KaiC, ...
Authors:Padua, R.A.P, Grant, T, Pitsawong, W, Hoemberger, M.S, Otten, R, Bradshaw, N, Grigorieff, N, Kern, D.
Deposit date:2023-01-22
Release date:2023-03-22
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:From primordial clocks to circadian oscillators.
Nature, 616, 2023
8V54
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BU of 8v54 by Molmil
Engaged conformation of the human mitochondrial DNA polymerase gamma bound to DNA
Descriptor: DNA (25-MER), DNA (44-MER), DNA polymerase subunit gamma-1, ...
Authors:Riccio, A.A, Krahn, J.M, Bouvette, J, Borgnia, J.M, Copeland, W.C.
Deposit date:2023-11-30
Release date:2024-07-10
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Coordinated DNA polymerization by Pol gamma and the region of LonP1 regulated proteolysis.
Nucleic Acids Res., 2024
8V55
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BU of 8v55 by Molmil
Human mitochondrial DNA polymerase gamma bound to a replication fork in an open conformation
Descriptor: DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ...
Authors:Riccio, A.A, Krahn, J.M, Bouvette, J, Borgnia, M.J, Copeland, W.C.
Deposit date:2023-11-30
Release date:2024-07-10
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Coordinated DNA polymerization by Pol gamma and the region of LonP1 regulated proteolysis.
Nucleic Acids Res., 2024
8V5R
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BU of 8v5r by Molmil
Active conformation of DNA polymerase gamma bound to DNA
Descriptor: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, ...
Authors:Riccio, A.A, Krahn, J.M, Bouvette, J, Borgnia, J.M, Copeland, W.C.
Deposit date:2023-11-30
Release date:2024-07-10
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Coordinated DNA polymerization by Pol gamma and the region of LonP1 regulated proteolysis.
Nucleic Acids Res., 2024
8FTH
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BU of 8fth by Molmil
Chaetomium thermophilum SETX - NPPC internal deletion
Descriptor: 5'-3' RNA helicase-like protein, ADENOSINE-5'-DIPHOSPHATE
Authors:Williams, R.S, Appel, C.D.
Deposit date:2023-01-12
Release date:2023-10-25
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Sen1 architecture: RNA-DNA hybrid resolution, autoregulation, and insights into SETX inactivation in AOA2.
Mol.Cell, 83, 2023
8FTK
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BU of 8ftk by Molmil
Chaetomium thermophilum SETX (Full-length)
Descriptor: 5'-3' RNA helicase-like protein
Authors:Williams, R.S, Appel, C.D.
Deposit date:2023-01-12
Release date:2023-10-25
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (4.56 Å)
Cite:Sen1 architecture: RNA-DNA hybrid resolution, autoregulation, and insights into SETX inactivation in AOA2.
Mol.Cell, 83, 2023
8FTM
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BU of 8ftm by Molmil
Setx-ssRNA-ADP-SO4 complex
Descriptor: 5'-3' RNA helicase-like protein, ADENOSINE-5'-DIPHOSPHATE, RNA (5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3'), ...
Authors:Williams, R.S, Appel, C.D.
Deposit date:2023-01-12
Release date:2023-10-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Sen1 architecture: RNA-DNA hybrid resolution, autoregulation, and insights into SETX inactivation in AOA2.
Mol.Cell, 83, 2023
3I9W
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BU of 3i9w by Molmil
Crystal structure of the E. coli histidine kinase sensor TorS sensor domain
Descriptor: Sensor protein torS
Authors:Moore, J.O, Hendrickson, W.A.
Deposit date:2009-07-13
Release date:2009-10-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural analysis of sensor domains from the TMAO-responsive histidine kinase receptor TorS
Structure, 17, 2009
5B70
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BU of 5b70 by Molmil
OxyR2 E204G regulatory domain from Vibrio vulnificus
Descriptor: GLYCEROL, LysR family transcriptional regulator
Authors:Jo, I, Ha, N.-C.
Deposit date:2016-06-02
Release date:2017-03-15
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The hydrogen peroxide hypersensitivity of OxyR2 in Vibrio vulnificus depends on conformational constraints
J. Biol. Chem., 292, 2017
3I9Y
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BU of 3i9y by Molmil
Crystal structure of the V. parahaemolyticus histidine kinase sensor TorS sensor domain
Descriptor: Sensor protein
Authors:Moore, J.O, Hendrickson, W.A.
Deposit date:2009-07-13
Release date:2009-10-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Structural analysis of sensor domains from the TMAO-responsive histidine kinase receptor TorS
Structure, 17, 2009
5TBZ
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BU of 5tbz by Molmil
E. Coli RNA Polymerase complexed with NusG
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Liu, B, Steitz, T.A.
Deposit date:2016-09-13
Release date:2016-12-07
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (7 Å)
Cite:Structural insights into NusG regulating transcription elongation.
Nucleic Acids Res., 45, 2017
6BCD
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BU of 6bcd by Molmil
Crystal structure of Rev7-K44A/R124A/A135D in complex with Rev3-RBM2 (residues 1988-2014)
Descriptor: DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B
Authors:Rizzo, A.A, Hao, B, Li, Y, Korzhnev, D.M.
Deposit date:2017-10-20
Release date:2018-08-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Rev7 dimerization is important for assembly and function of the Rev1/Pol zeta translesion synthesis complex.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8IGR
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BU of 8igr by Molmil
Cryo-EM structure of CII-dependent transcription activation complex
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zhao, M, Gao, B, Wen, A, Feng, Y, Lu, Y.
Deposit date:2023-02-21
Release date:2023-05-17
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of lambda CII-dependent transcription activation.
Structure, 31, 2023
6BC8
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BU of 6bc8 by Molmil
Crystal structure of Rev7-R124A/Rev3-RBM2 (residues 1988-2014) complex
Descriptor: ACETATE ION, DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B, ...
Authors:Rizzo, A.A, Hao, B, Li, Y, Korzhnev, D.M.
Deposit date:2017-10-20
Release date:2018-08-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Rev7 dimerization is important for assembly and function of the Rev1/Pol zeta translesion synthesis complex.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7QQY
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BU of 7qqy by Molmil
yeast Gid10 bound to Art2 Pro/N-degron
Descriptor: CHLORIDE ION, ECM21, Uncharacterized protein YGR066C
Authors:Chrustowicz, J, Sherpa, D, Schulman, B.A.
Deposit date:2022-01-10
Release date:2022-03-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:A GID E3 ligase assembly ubiquitinates an Rsp5 E3 adaptor and regulates plasma membrane transporters.
Embo Rep., 23, 2022
6XZ5
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BU of 6xz5 by Molmil
RovC - regulator of virulence interconnected with the Csr system
Descriptor: SULFATE ION, Uncharacterized protein,RovC,Uncharacterized protein
Authors:Sadana, P, Scrima, A.
Deposit date:2020-02-02
Release date:2020-09-16
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:RovC - a novel type of hexameric transcriptional activator promoting type VI secretion gene expression.
Plos Pathog., 16, 2020
5B7D
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BU of 5b7d by Molmil
OxyR2 E204G mutant regulatory domain from Vibrio vulnificus (sulfate-bound)
Descriptor: LysR family transcriptional regulator, SULFATE ION
Authors:Jo, I, Ha, N.-C.
Deposit date:2016-06-07
Release date:2017-03-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:The hydrogen peroxide hypersensitivity of OxyR2 in Vibrio vulnificus depends on conformational constraints
J. Biol. Chem., 292, 2017
3FVQ
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BU of 3fvq by Molmil
Crystal structure of the nucleotide binding domain FbpC complexed with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Fe(3+) ions import ATP-binding protein fbpC
Authors:Newstead, S, Bilton, P, Carpenter, E.P, Campopiano, D, Iwata, S.
Deposit date:2009-01-16
Release date:2009-08-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Insights into how nucleotide-binding domains power ABC transport.
Structure, 17, 2009
6BI7
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BU of 6bi7 by Molmil
Crystal structure of Rev7-WT/Rev3 as a monomer under high-salt conditions
Descriptor: DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B
Authors:Rizzo, A.A, Korzhnev, D.M, Hao, B, Li, Y.
Deposit date:2017-11-01
Release date:2018-08-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Rev7 dimerization is important for assembly and function of the Rev1/Pol zeta translesion synthesis complex.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018

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