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5U30
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BU of 5u30 by Molmil
Crystal structure of AacC2c1-sgRNA-extended target DNA ternary complex
Descriptor: CRISPR-associated endonuclease C2c1, Non-target DNA strand, SULFATE ION, ...
Authors:Yang, H, Gao, P, Rajashankar, K.R, Patel, D.J.
Deposit date:2016-12-01
Release date:2017-01-25
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:PAM-Dependent Target DNA Recognition and Cleavage by C2c1 CRISPR-Cas Endonuclease.
Cell, 167, 2016
5E9J
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BU of 5e9j by Molmil
Crystal structure of the mRNA cap guanine-N7 methyltransferase - modular lobe (416-456) deletion
Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, mRNA cap guanine-N7 methyltransferase,mRNA cap guanine-N7 methyltransferase
Authors:Petit, P, Cowling, V.H.
Deposit date:2015-10-15
Release date:2016-07-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.47 Å)
Cite:Molecular basis of RNA guanine-7 methyltransferase (RNMT) activation by RAM.
Nucleic Acids Res., 44, 2016
6S2C
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BU of 6s2c by Molmil
Acquired functional capsid structures in metazoan totivirus-like dsRNA virus.
Descriptor: Capsid protein
Authors:Okamoto, K, Larsson, S.D.D, Maia, R.N.C.F, Murata, K, Hajdu, J, Iwasaki, K, Miyazaki, N.
Deposit date:2019-06-20
Release date:2020-04-29
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Acquired Functional Capsid Structures in Metazoan Totivirus-like dsRNA Virus.
Structure, 28, 2020
3KIO
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BU of 3kio by Molmil
mouse RNase H2 complex
Descriptor: Ribonuclease H2 subunit A, Ribonuclease H2 subunit B, Ribonuclease H2 subunit C
Authors:Shaban, N, Harvey, S, Perrino, F.W, Hollis, T.
Deposit date:2009-11-02
Release date:2009-11-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The structure of the mammalian RNase H2 complex provides insight into RNA:DNA hybrid processing to prevent immune dysfunction.
J.Biol.Chem., 285, 2010
3GIB
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BU of 3gib by Molmil
Crystal Structure of the Complex of the E. coli Hfq with Poly(A)
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*A)-3', Protein hfq
Authors:Link, T.M, Valentin-Hansen, P, Brennan, R.G.
Deposit date:2009-03-05
Release date:2009-11-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of Escherichia coli Hfq bound to polyriboadenylate RNA
Proc.Natl.Acad.Sci.USA, 106, 2009
1UP1
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BU of 1up1 by Molmil
UP1, THE TWO RNA-RECOGNITION MOTIF DOMAIN OF HNRNP A1
Descriptor: HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1
Authors:Xu, R.-M, Jokhan, L, Cheng, X, Mayeda, A, Krainer, A.R.
Deposit date:1997-03-12
Release date:1997-09-17
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of human UP1, the domain of hnRNP A1 that contains two RNA-recognition motifs.
Structure, 5, 1997
8F24
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BU of 8f24 by Molmil
Mirror-image RNA octamer containing 2'-OMe-L-uridine
Descriptor: Mirror-image RNA 0G-XEC-0G-0U-0A-0C-0A-0C, SULFATE ION
Authors:Dantsu, Y, Zhang, W.
Deposit date:2022-11-07
Release date:2023-04-12
Last modified:2024-04-17
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Derivatization of Mirror-Image l-Nucleic Acids with 2'-OMe Modification for Thermal and Structural Stabilization.
Chembiochem, 24, 2023
8T2B
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BU of 8t2b by Molmil
Crystal structure of SCV PTE G18C mutant RNA in complex with Fab BL3-6
Descriptor: BL3-6 Fab heavy chain, BL3-6 Fab light chain, RNA (90-MER)
Authors:Ojha, M, Koirala, D.
Deposit date:2023-06-05
Release date:2024-01-10
Method:X-RAY DIFFRACTION (3.18 Å)
Cite:Crystal structure of SCV PTE G18C mutant RNA in complex with Fab BL3-6
To Be Published
8T2A
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BU of 8t2a by Molmil
Crystal structure of SCV PTE G18A mutant RNA in complex with Fab BL3-6
Descriptor: BL3-6 Fab heavy chain, BL3-6 Fab light chain, RNA (90-MER)
Authors:Ojha, M, Koirala, D.
Deposit date:2023-06-05
Release date:2024-01-10
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:Crystal structure of SCV PTE G18A mutant RNA in complex with Fab BL3-6
To Be Published
8T2O
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BU of 8t2o by Molmil
Crystal structure of SCV PTE G18U RNA in complex with Fab BL3-6
Descriptor: BL3-6 Fab heavy chain, BL3-6 Fab light chain, RNA (90-MER)
Authors:Ojha, M, Koirala, D.
Deposit date:2023-06-06
Release date:2024-01-10
Method:X-RAY DIFFRACTION (3.29 Å)
Cite:Crystal structure of SCV PTE G18U RNA in complex with Fab BL3-6
To Be Published
8T29
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BU of 8t29 by Molmil
Crystal structure of SCV PTE RNA in complex with Fab BL3-6
Descriptor: BL3-6 Fab heavy chain, BL3-6 Fab light chain, RNA (90-MER)
Authors:Ojha, M, Koirala, D.
Deposit date:2023-06-05
Release date:2024-01-10
Method:X-RAY DIFFRACTION (3.13 Å)
Cite:Crystal structure of SCV PTE RNA in complex with Fab BL3-6
To Be Published
2MMY
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BU of 2mmy by Molmil
Solution structure of the RNA recognition motif of human TAF15
Descriptor: TATA-binding protein-associated factor 2N
Authors:Kashyap, M, Ganguly, A.K, Bhavesh, N.S.
Deposit date:2014-03-22
Release date:2015-03-25
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural delineation of stem-loop RNA binding by human TAF15 protein
Sci Rep, 5, 2015
6IZP
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BU of 6izp by Molmil
Solution structure of the complex of naphthyridine carbamate dimer and an RNA with UGGAA-UGGAA pentad
Descriptor: 3-[3-[(7-methyl-1,8-naphthyridin-2-yl)carbamoyloxy]propylamino]propyl ~{N}-(7-methyl-1,8-naphthyridin-2-yl)carbamate, RNA (29-MER)
Authors:Nagano, K, Shibata, T, Nakatani, K, Kawai, G.
Deposit date:2018-12-20
Release date:2019-12-25
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Small molecule targeting r(UGGAA)n disrupts RNA foci and alleviates disease phenotype in Drosophila model
Nat Commun, 12, 2021
1BIV
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BU of 1biv by Molmil
BOVINE IMMUNODEFICIENCY VIRUS TAT-TAR COMPLEX, NMR, 5 STRUCTURES
Descriptor: TAR RNA, TAT PEPTIDE
Authors:Ye, X, Kumar, R.A, Patel, D.J.
Deposit date:1996-06-12
Release date:1996-12-23
Last modified:2024-04-10
Method:SOLUTION NMR
Cite:Molecular recognition in the bovine immunodeficiency virus Tat peptide-TAR RNA complex.
Chem.Biol., 2, 1995
3IYB
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BU of 3iyb by Molmil
Poliovirus early RNA-release intermediate
Descriptor: Genome polyprotein, Precursor polyprotein, VP1 core
Authors:Levy, H.C, Bostina, M, Filman, D.J, Hogle, J.M.
Deposit date:2009-07-21
Release date:2010-03-16
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Catching a virus in the act of RNA release: a novel poliovirus uncoating intermediate characterized by cryo-electron microscopy.
J.Virol., 84, 2010
5JCH
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BU of 5jch by Molmil
Crystal structure of chicken MDA5 with 5'p 10-mer dsRNA and ADP-Mg2+ at 2.95 A resolution (untwinned).
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Melanoma differentiation associated protein-5, ...
Authors:Cusack, S, Uchikawa, E.
Deposit date:2016-04-15
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
5JC3
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BU of 5jc3 by Molmil
Crystal structure of chicken MDA5 with 5'p 10-mer dsRNA and ADP-Mg2+ at 2.6 A resolution (monoclinic form, twinned).
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Melanoma differentiation associated protein-5, ...
Authors:Cusack, S, Uchikawa, E.
Deposit date:2016-04-14
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
2O3D
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BU of 2o3d by Molmil
Structure of human SF2/ASF RNA recognition motif 2 (RRM2)
Descriptor: Splicing factor, arginine/serine-rich 1
Authors:Tintaru, A.M, Hautbergue, G.M, Hounslow, A.M, Lian, L.Y, Craven, C.J, Wilson, S.A.
Deposit date:2006-12-01
Release date:2007-10-16
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Structural and functional analysis of RNA and TAP binding to SF2/ASF.
Embo Rep., 8, 2007
2ZTT
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BU of 2ztt by Molmil
Crystal Structure of RNA polymerase PB1-PB2 subunits from Influenza A Virus
Descriptor: Polymerase basic protein 2, RNA-directed RNA polymerase catalytic subunit
Authors:Sugiyama, K, Obayashi, E, Park, S.-Y.
Deposit date:2008-10-08
Release date:2009-06-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural insight into the essential PB1-PB2 subunit contact of the influenza virus RNA polymerase
Embo J., 28, 2009
4PCJ
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BU of 4pcj by Molmil
Modifications to toxic CUG RNAs induce structural stability and rescue mis-splicing in Myotonic Dystrophy
Descriptor: MAGNESIUM ION, trCUG-3('5)
Authors:Coonrod, L.A, Reister, E.E, Berglund, J.A.
Deposit date:2014-04-15
Release date:2014-10-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Modifications to toxic CUG RNAs induce structural stability, rescue mis-splicing in a myotonic dystrophy cell model and reduce toxicity in a myotonic dystrophy zebrafish model.
Nucleic Acids Res., 42, 2014
3OL8
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BU of 3ol8 by Molmil
Poliovirus polymerase elongation complex with CTP-Mn
Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, MANGANESE (II) ION, ...
Authors:Gong, P, Peersen, O.B.
Deposit date:2010-08-25
Release date:2010-12-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase.
Proc.Natl.Acad.Sci.USA, 107, 2010
3OLA
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BU of 3ola by Molmil
Poliovirus polymerase elongation complex with 2'-deoxy-CTP
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, DNA/RNA (5'-R(*GP*CP*CP*CP*GP*GP*AP*CP*GP*AP*GP*AP*GP*A)-D(P*C)-3'), ...
Authors:Gong, P, Peersen, O.B.
Deposit date:2010-08-25
Release date:2010-12-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase.
Proc.Natl.Acad.Sci.USA, 107, 2010
3CDU
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BU of 3cdu by Molmil
Crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase (3Dpol) in complex with a pyrophosphate
Descriptor: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
Authors:Gruez, A, Selisko, B, Roberts, M, Bricogne, G, Bussetta, C, Canard, B.
Deposit date:2008-02-27
Release date:2008-07-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases
J.Virol., 82, 2008
2ADC
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BU of 2adc by Molmil
Solution structure of Polypyrimidine Tract Binding protein RBD34 complexed with CUCUCU RNA
Descriptor: 5'-R(*CP*UP*CP*UP*CP*U)-3', Polypyrimidine tract-binding protein 1
Authors:Oberstrass, F.C, Auweter, S.D, Erat, M, Hargous, Y, Henning, A, Wenter, P, Reymond, L, Pitsch, S, Black, D.L, Allain, F.H.T.
Deposit date:2005-07-20
Release date:2005-10-04
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure of PTB bound to RNA: specific binding and implications for splicing regulation
Science, 309, 2005
1HAV
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BU of 1hav by Molmil
HEPATITIS A VIRUS 3C PROTEINASE
Descriptor: CHLORIDE ION, HEPATITIS A VIRUS 3C PROTEINASE
Authors:Bergmann, E.M, James, M.N.G.
Deposit date:1996-10-23
Release date:1996-12-23
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:The refined crystal structure of the 3C gene product from hepatitis A virus: specific proteinase activity and RNA recognition.
J.Virol., 71, 1997

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