5E9J

Crystal structure of the mRNA cap guanine-N7 methyltransferase - modular lobe (416-456) deletion

Summary for 5E9J

• Entry DOI: 10.2210/pdb5e9j/pdb
• Related: 5e8j
• Descriptor: mRNA cap guanine-N7 methyltransferase,mRNA cap guanine-N7 methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE (2 entities in total)
• Functional Keywords: mrna capping, rna processing, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 65325.14

Authors

Petit, P.,Cowling, V.H. (deposition date: 2015-10-15, release date: 2016-07-13, Last modification date: 2024-01-10)

• Primary citation: Varshney, D.,Petit, A.P.,Bueren-Calabuig, J.A.,Jansen, C.,Fletcher, D.A.,Peggie, M.,Weidlich, S.,Scullion, P.,Pisliakov, A.V.,Cowling, V.H.; Molecular basis of RNA guanine-7 methyltransferase (RNMT) activation by RAM.; Nucleic Acids Res., 44:10423-10436, 2016; PubMed: 27422871; DOI: 10.1093/nar/gkw637

Experimental method

X-RAY DIFFRACTION (3.47 Å)