5E9J

Crystal structure of the mRNA cap guanine-N7 methyltransferase - modular lobe (416-456) deletion

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	mRNA cap guanine-N7 methyltransferase,mRNA cap guanine-N7 methyltransferase	polymer	274	32278.2	2	UniProt (O43148) Pfam (PF03291)	Homo sapiens (Human)	RG7MT1,mRNA (guanine-N(7)-)-methyltransferase,mRNA cap methyltransferase,hcm1p,RG7MT1,mRNA (guanine-N(7)-)-methyltransferase,mRNA cap methyltransferase,hcm1p
2	C, D (A, B)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	2	Chemie (SAH) PubChem (193) PubChem (13792) PubChem (189149) PubChem (439155) PubChem (5284331) PubChem (71170554) PubChem (13231890) PubChem (16760024) PubChem (25210495) PubChem (44361184) PubChem (177678424) PubChem (46936206) PubChem (21125603) PubChem (25203782) PubChem (52224400) PubChem (50989525) PubChem (51380914) PubChem (52224398) PubChem (6419189) PubChem (57544532) PubChem (59046843) PubChem (59170628) PubChem (164157219) PubChem (59576228) PubChem (66805708) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (118374891) PubChem (118560068) PubChem (126969526) PubChem (129105892) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525)

Sequence modifications

A, B: 167 - 416 (UniProt: O43148)
A, B: 421 - 440 (UniProt: O43148)

PDB	External Database	Details
Gly 417	-	linker
Gly 418	-	linker
Ser 419	-	linker
Gly 420	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	64556.3
Non-Polymers*	Number of molecules	2
	Total formula weight	768.8
All*	Total formula weight	65325.1

*Water molecules are not included.