5E9J

Crystal structure of the mRNA cap guanine-N7 methyltransferase - modular lobe (416-456) deletion

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	mRNA cap guanine-N7 methyltransferase,mRNA cap guanine-N7 methyltransferase	polymer	274	32278.2	2	UniProt (O43148) Pfam (PF03291)	Homo sapiens (Human)	RG7MT1,mRNA (guanine-N(7)-)-methyltransferase,mRNA cap methyltransferase,hcm1p,RG7MT1,mRNA (guanine-N(7)-)-methyltransferase,mRNA cap methyltransferase,hcm1p
2	C, D (A, B)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	2	Chemie (SAH)

Sequence modifications

A, B: 167 - 416 (UniProt: O43148)
A, B: 421 - 440 (UniProt: O43148)

PDB	External Database	Details
Gly 417	-	linker
Gly 418	-	linker
Ser 419	-	linker
Gly 420	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	64556.3
Non-Polymers*	Number of molecules	2
	Total formula weight	768.8
All*	Total formula weight	65325.1

*Water molecules are not included.