5E9J
Crystal structure of the mRNA cap guanine-N7 methyltransferase - modular lobe (416-456) deletion
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue SAH A 501 |
| Chain | Residue |
| A | LYS180 |
| A | PHE285 |
| A | VAL286 |
| A | TYR289 |
| A | GLY205 |
| A | CYS206 |
| A | GLY207 |
| A | ASP227 |
| A | ILE228 |
| A | ASP261 |
| A | SER262 |
| A | GLN284 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | binding site for residue SAH B 501 |
| Chain | Residue |
| B | LYS180 |
| B | GLY205 |
| B | GLY207 |
| B | ASP211 |
| B | ASP227 |
| B | ILE228 |
| B | ASP261 |
| B | SER262 |
| B | GLN284 |
| B | PHE285 |
| B | VAL286 |
| B | TYR289 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00895 |
| Chain | Residue | Details |
| A | ASN176 | |
| B | ASN176 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00895, ECO:0000269|PubMed:27422871, ECO:0007744|PDB:3BGV, ECO:0007744|PDB:5E9J, ECO:0007744|PDB:5E9W |
| Chain | Residue | Details |
| A | LYS180 | |
| A | GLY205 | |
| A | ASP227 | |
| B | LYS180 | |
| B | GLY205 | |
| B | ASP227 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:27422871, ECO:0007744|PDB:3BGV, ECO:0007744|PDB:5E9J, ECO:0007744|PDB:5E9W |
| Chain | Residue | Details |
| A | ASP261 | |
| A | GLN284 | |
| A | TYR289 | |
| B | ASP261 | |
| B | GLN284 | |
| B | TYR289 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | SITE: mRNA cap binding => ECO:0000255|PROSITE-ProRule:PRU00895 |
| Chain | Residue | Details |
| A | LYS208 | |
| B | HIS288 | |
| B | GLU370 | |
| B | TYR431 | |
| A | LYS214 | |
| A | ARG239 | |
| A | HIS288 | |
| A | GLU370 | |
| A | TYR431 | |
| B | LYS208 | |
| B | LYS214 | |
| B | ARG239 |
