1BIV
BOVINE IMMUNODEFICIENCY VIRUS TAT-TAR COMPLEX, NMR, 5 STRUCTURES
Summary for 1BIV
| Entry DOI | 10.2210/pdb1biv/pdb |
| Descriptor | TAR RNA, TAT PEPTIDE (2 entities in total) |
| Functional Keywords | tat-tar, arg-gua interactions, buttressing u(dot)au base triple, glycine and isoleucine packing, peptide rna recognition, rna bending, complex (ribonucleic acid-peptide), viral protein-rna complex, viral protein/rna |
| Biological source | synthetic construct More |
| Total number of polymer chains | 2 |
| Total formula weight | 10894.64 |
| Authors | Ye, X.,Kumar, R.A.,Patel, D.J. (deposition date: 1996-06-12, release date: 1996-12-23, Last modification date: 2024-04-10) |
| Primary citation | Ye, X.,Kumar, R.A.,Patel, D.J. Molecular recognition in the bovine immunodeficiency virus Tat peptide-TAR RNA complex. Chem.Biol., 2:827-840, 1995 Cited by PubMed Abstract: In lentiviruses such as human immunodeficiency virus (HIV) and bovine immunodeficiency virus (BIV), the Tat (trans-activating) protein enhances transcription of the viral RNA by complexing to the 5'-end of the transcribed mRNA, at a region known as TAR (the trans-activation response element). Identification of the determinants that account for specific molecular recognition requires a high resolution structure of the Tat peptide-TAR RNA complex. PubMed: 8807816DOI: 10.1016/1074-5521(95)90089-6 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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