3KIO

mouse RNase H2 complex

Summary for 3KIO

Entry DOI	10.2210/pdb3kio/pdb
Descriptor	Ribonuclease H2 subunit A, Ribonuclease H2 subunit B, Ribonuclease H2 subunit C, ... (4 entities in total)
Functional Keywords	ribonuclease, aicardi-goutieres syndrome, rnase h2, protein complex, autoimmune disease, endonuclease, hydrolase, metal-binding, nuclease, nucleus, phosphoprotein, acetylation
Biological source	Mus musculus (mouse) More
Cellular location	Nucleus (By similarity): Q9CWY8 Q80ZV0 Q9CQ18
Total number of polymer chains	3
Total formula weight	89509.58
Authors	Shaban, N.,Harvey, S.,Perrino, F.W.,Hollis, T. (deposition date: 2009-11-02, release date: 2009-11-17, Last modification date: 2011-07-13)
Primary citation	Shaban, N.M.,Harvey, S.,Perrino, F.W.,Hollis, T. The structure of the mammalian RNase H2 complex provides insight into RNA:DNA hybrid processing to prevent immune dysfunction. J.Biol.Chem., 285:3617-3624, 2010 Cited by PubMed: 19923215 DOI: 10.1074/jbc.M109.059048 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation